Congenital cutaneous candidiasis associated with respiratory distress and elevation of liver function tests: A case report and review of the literature - 11/09/11
Abstract |
We describe congenital cutaneous candidiasis (CCC) in a term newborn. The mother had candidal vaginitis 1 week before delivery. At birth, the infant had a generalized, intensely erythematous, papulovesicular eruption, respiratory distress and elevation of liver function tests. The child responded well to intravenous amphotericin B plus topical and oral nystatin. There have been 13 previously reported cases of CCC in infants weighing more than 1500 gm who had evidence of systemic infection. Two deaths were attributed to candidal pneumonia and sepsis. The majority of infants with CCC have infection localized to the skin, but if there is any evidence of respiratory distress or signs of sepsis the possibility of systemic candidiasis and the need for parenteral antifungal therapy must be considered. (J Am Acad Dermatol 1997;37:817-23.)
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This article is made possible through an educational grant from the Dermatological Division, Ortho Pharmaceutical Corporation. |
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Reprint requests: Franklin P. Flowers, MD, Division of Dermatology and Cutaneous Surgery, PO Box 100277, Gainesville, FL 32610-0277. |
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0190-9622/97/$5.00 + 0 16/4/80731 |
Vol 37 - N° 5P2
P. 817-823 - novembre 1997 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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