Monitoring low-dose warfarin therapy by a central laboratory and implications for clinical trials and patient care - 11/09/11
Doi : 10.1016/S0002-9149(96)00543-7
Gary E. Raskob, MS a, b, 1, Sherri S. Durica, MD a, b, Willis L. Owen, PhD a, b, Philip C. Comp, MD, PhD a, b
The Coumadin Aspirin Reinfarction (CARS) Pilot Study Groupab
a From the Clinical Epidemiology Unit, Departments of Medicine and Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center U.S.A.
b From the Veterans Administration Medical Center, Oklahoma City, Oklahoma, U.S.A.
Abstract |
In conclusion, the central laboratory provides INR results in close agreement with the local laboratory for monitoring the anticoagulant effect of low-dose warfarin. The findings suggest further evaluation of the central laboratory to monitor adjusted warfarin therapy at currently recommended therapeutic ranges.13 The cost-effectiveness of using a central laboratory should also be evaluated.
Le texte complet de cet article est disponible en PDF. | This study was supported by grants from the National Institute of Health (HL-30443) and a National Institutes of Health Institutional Development Award (IdeA); by Applied Research Grant AR2–051 from the Oklahoma Center for the Advancement of Science and Technology; and by a grant from the Du Pont Merck Pharmaceutical Company. This work was performed during the tenure of a fellowship from the Presbyterian Health Foundation (S.S.D.), and was supported by National Research Service Award HL 08756-02 from the National Heart, Lung, and Blood Institute. |
© 1996
Publié par Elsevier Masson SAS.
Vol 78 - N° 9
P. 1074-1076 - novembre 1996 Retour au numéro
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