Supplementation with omega-3 polyunsaturated fatty acids in the management of dysmenorrhea in adolescents - 11/09/11
Abstract |
OBJECTIVES: The purpose of the study was to examine whether dietary supplementation with omega-3 fatty acids can relieve symptoms of dysmenorrhea in adolescents. STUDY DESIGN: Forty-two adolescents with dysmenorrhea were randomly allocated to two groups. In the first group 21 girls received fish oil (1080 mg icosapentaenoic acid, 720 mg docosahexaenoic acid, and 1.5 mg vitamin E) daily for 2 months followed by a placebo for an additional 2 months. In the second group 21 girls received placebo for the first 2 months, followed by fish oil for 2 more months. The Cox Menstrual Symptom Scale was used to assess response to treatment. RESULTS: There were no significant differences in the Cox Menstrual Symptom Scale between the two groups at baseline after 2 months of placebo administration. After 2 months of treatment with fish oil there was a marked reduction in the Cox Menstrual Symptom Scale from a baseline mean value of 69.9 to 44.0 (p < 0.0004). CONCLUSIONS: This study suggests that dietary supplementation with omega-3 fatty acids has a beneficial effect on symptoms of dysmenorrhea in adolescents. (AM J OBSTET GYNECOL 1996;174:1335-8.)
Le texte complet de cet article est disponible en PDF.Keywords : Omega-3 fatty acids (fish oil), dysmenorrhea
Plan
| ☆ | From the Division of Adolescent Medicine, Children's Hospital Medical Center,aand the Department of Pediatrics, University of Cincinnati Medical Center.b |
| ☆☆ | Supported in part by Maternal and Child Health grant MCJ-00964 and National Institutes of Health grant AI35087. |
| ★ | Reprint requests: Frank M. Biro, MD, Division of Adolescent Medicine, Children's Hospital Medical Center, 3333 Burnet Ave., Cincinnati, OH 45229. |
| ★★ | 0002-9378/96 $5.00 + 0 6/1/69360 |
Vol 174 - N° 4
P. 1335-1338 - avril 1996 Retour au numéro
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