Simultaneous Topography-Guided Photorefractive Keratectomy Followed by Corneal Collagen Cross-linking for Keratoconus - 19/10/11
, Dimitra M. Portaliou, George A. Kounis, Aliki N. Limnopoulou, Georgios A. Kontadakis, Michael A. Grentzelos
Inquiries to George D. Kymionis, Institute of Vision and Optics, University of Crete, Medical School, 71003 Heraklion, Crete, GreeceRésumé |
Purpose |
To present the long-term results after simultaneous photorefractive keratectomy followed by corneal collagen cross-linking for keratoconus.
Design |
Prospective, interventional, consecutive case series.
Methods |
In this study, 26 patients (31 eyes) with progressive keratoconus were included. All patients underwent customized topography-guided photorefractive keratectomy immediately followed by corneal collagen cross-linking with the use of riboflavin and ultraviolet A irradiation. Epithelium was removed by transepithelial phototherapeutic keratectomy in all cases.
Results |
Mean follow-up was 19.53 ± 3.97 months (range, 12 to 25 months). Mean preoperative spherical equivalent was −2.3 ± 2.8 diopters (D), whereas at the last follow-up examination, it was significantly (P < .001) reduced to −1.08 ± 2.41 D. Logarithm of the minimal angle of resolution uncorrected and best-corrected visual acuity were reduced significantly by 0.46 and 0.084 (P < .001), respectively, at the last follow-up examination. Finally, mean steep and flat keratometry readings were reduced by 2.35 (P < .001) and 1.18 (P = .013) at the last follow-up examination.
Conclusions |
Simultaneous photorefractive keratectomy followed by corneal collagen cross-linking seems to be a promising treatment alternative in our series of keratoconic patients.
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Vol 152 - N° 5
P. 748-755 - novembre 2011 Retour au numéro
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