Mupirocin resistance is not an inevitable consequence of mupirocin use - 11/11/11
Corresponding author. Address: Service d’Hygiène Hospitalière, Centre Hospitalier Universitaire Besançon, 3 Bd Fleming, 25030 Besançon, Cedex, France. Tel.: +33 3 81669053; fax: +33 3 81668914.J.A. Child
Summary |
The rate of mupirocin resistance in meticillin-resistant Staphylococcus aureus (MRSA) in Besançon University Hospital is low with a decreasing trend, from 10% in 2004 to 3% in 2009. This trend in resistance paralleled mupirocin consumption. Genotyping results showed that this decrease was not linked to a change in MRSA clones. It appears that the way in which the mupirocin is used, rather than the volume, plays a role in the emergence of resistance and that its cautious use is likely to maintain the mupirocin resistance at a low level, thus preserving its efficacy.
Le texte complet de cet article est disponible en PDF.Keywords : Genotyping, Meticillin-resistant Staphylococcus aureus, Mupirocin, Resistance
Plan
Vol 79 - N° 4
P. 366-367 - décembre 2011 Retour au numéro
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