Detection and Quantification of Molecular Calcification by PET/Computed Tomography: A New Paradigm in Assessing Atherosclerosis - 26/11/11

Résumé |
Atherosclerotic plaque rupture is the leading cause of acute coronary syndrome. Molecular calcification represent as one of the early stages of plaque evolution has been hypothesized to play a potential role in atherosclerotic plaque instability and subsequent rupture. Several invasive and non-invasive structural imaging techniques have been utilized to diagnose atherosclerosis, but none of these methods are capable of detecting and quantifying molecular calcification. Fluorine-18-Sodium Fluoride (18F-NaF) positron emission tomography/computed tomography (PET/CT) imaging allows detection and quantification of arterial molecular calcification in heart and across multiple vessels. In this review the authors discuss the feasibility, application and potential future of 18F-NaF-PET/CT in detecting molecular calcification and in defining the future risk of atherosclerotic plaque rupture in the affected vessels.
Le texte complet de cet article est disponible en PDF.Keywords : Molecular calcification, 18F-Sodium fluoride, Atherogenesis, Atherosclerosis
Plan
Vol 6 - N° 4
P. 409-415 - octobre 2011 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?
