Computer-based classification of small colorectal polyps by using narrow-band imaging with optical magnification - 02/12/11
Reprint requests: Jens J.W. Tischendorf, MD, Medical Department III (Gastroenterology, Hepatology, and Metabolic Diseases), University Hospital Aachen, RWTH Aachen University, Pauwelsstraβe 30, D-52074 Aachen, GermanyRésumé |
Background |
Recent studies have shown that narrow-band imaging (NBI) is a powerful diagnostic tool for the differentiation between neoplastic and non-neoplastic colorectal polyps.
Objective |
To develop a computer-based method for classification of colorectal polyps.
Design |
A prospective study.
Setting |
University hospital.
Patients |
A total of 214 patients with colorectal polyps who underwent a zoom NBI colonoscopy.
Interventions |
A total of 434 detected polyps 10 mm or smaller were imaged and subsequently removed for histological analysis.
Main Outcome Measurements |
Diagnostic performance in polyp classification by 2 experts, 2 nonexperts, and a computer-based algorithm.
Results |
The expert group and the computer-based algorithm achieved a comparable diagnostic performance (expert group: 93.4% sensitivity, 91.8% specificity, and 92.7% accuracy; computer-based algorithm: 95.0% sensitivity, 90.3% specificity, and 93.1% accuracy) and were both significantly superior to the nonexpert group (86.0% sensitivity, 87.8% specificity, and 86.8% accuracy) in terms of sensitivity, negative predictive value, and accuracy. Subgroup analysis of 255 polyps 5 mm or smaller revealed comparable results without significant differences in the overall analysis of all polyps.
Limitations |
No fully automatic classification system.
Conclusions |
The study demonstrates that computer-based classification of colon polyps can be achieved with high diagnostic performance.
Le texte complet de cet article est disponible en PDF.Abbreviation : NBI
Plan
| DISCLOSURE: All authors disclosed no financial relationships relevant to this publication. Drs Gross, Trautwein, Aach, and Tischendorf were supported by the German Federal Ministry of Education and Research. |
Vol 74 - N° 6
P. 1354-1359 - décembre 2011 Retour au numéro
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