Changing trend in surgical indication and management for Graves' disease - 23/01/12
, Chung-Yau Lo, M.S., F.R.C.S.
Corresponding author. Tel.: +852-22554773; fax: +852-28172291Abstract |
Background |
Although thyroidectomy for Graves' disease (GD) is well established, surgical indications remain less well defined. This study aimed to evaluate the changes in surgical indication, type of resection, and surgical outcomes at a single institution.
Methods |
A total of 346 patients who underwent thyroidectomy for GD were divided into 2 time periods: period 1 (1995–2001) and period 2 (2002–2008). Their surgical indication, type of resection, and surgical outcomes were compared.
Results |
Patients in the earlier period were significantly younger, suffered more previous relapses, and were on a longer duration of antithyroid drugs before surgery. Graves' ophthalmopathy and refusal for radioactive iodine were the indications that changed significantly between the 2 periods. Total/near-total thyroidectomy was performed more commonly and resulted in a higher temporary hypoparathyroidism rate in the latter period (P < .001).
Conclusions |
Over the study period, significant changes in surgical indication, type of resection, and surgical outcomes were noted. Graves' ophthalmopathy became one of the most common surgical indications. Total thyroidectomy became the preferred surgery but that resulted in a higher temporary hypoparathyroidism rate.
Le texte complet de cet article est disponible en PDF.Keywords : Thyroidectomy, Graves' disease, Graves' ophthalmopathy, Postoperative hypocalcemia, Hyperthyroidism, Radioiodine treatment
Plan
Vol 203 - N° 2
P. 162-167 - février 2012 Retour au numéro
Article précédent
- Surgical management of radiation-induced angiosarcoma after breast conservation therapy
- Navid Jallali, Stuart James, Adam Searle, Amar Ghattaura, Andrew Hayes, Paul Harris
- Multidrug donor preconditioning protects steatotic liver grafts against ischemia-reperfusion injury
- Maximilian von Heesen, Katharina Seibert, Matthias Hülser, Claudia Scheuer, Mathias Wagner, Michael Dieter Menger, Martin Karl Schilling, Mohammed Reza Moussavian
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?