Baroreflex Sensitivity is Associated with Sleep-Related Breathing Problems in Adolescents - 15/03/12
Reprint requests: Deborah D. O’Leary, PhD, Department of Community Health Sciences, Brock University, St Catharines, 500 Glenridge Avenue, St Catharines, Ontario, Canada, L2S 3A1.Abstract |
Objectives |
To examine the relationship between sleep-related breathing problems (SRBPs) and baroreflex sensitivity (BRS) among adolescents and assesses whether body mass influences this relationship.
Study design |
SRBPs were assessed in 106 adolescents aged 11-14 years using the Pediatric Sleep Questionnaire. Body mass index (BMI) was calculated, and 5 minutes of continuous beat-to-beat blood pressure (Finapres) and R-R interval were recorded (standard electrocardiogram) after 15 minutes of supine rest. Spectral indices were computed using fast Fourier transform, and transfer function analysis was used to compute BRS.
Results |
Regression analyses indicate an interaction between BMI and SRBPs (b=−.151, P=.015) on BRS. Graphing the interaction showed that those with higher SRBP scores had lower BRS but that this effect was stronger for those with higher BMI.
Conclusions |
Adolescents with elevated SRBP scores had lower BRS. In addition, higher BMI amplified the risk of higher SRBP scores on BRS.
Le texte complet de cet article est disponible en PDF.Mots-clés : aPHV, BMI, BP, BRS, DBP, HF, HRV, LF, OSAS, PSG, PSQ, RRI, SBP, SRBP
Plan
| Financial support was provided by the Heart and Stroke Foundation of Ontario (SDA6237), the Canada Research Chairs program (to T.W.), the Canadian Foundation for Innovation (10118), the Canadian Institutes of Health Research (to N.C.), and an endowed professorship through the Department of Family Medicine from McMaster University (to J.C.). The authors declare no conflicts of interest. |
Vol 160 - N° 4
P. 610 - avril 2012 Retour au numéro
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