Closed-Loop Insulin Delivery in Type 1 Diabetes - 09/05/12
Corresponding author.Résumé |
Advances in diabetes technology have led to significant improvements in the quality of life and care received by individuals with diabetes. Despite this, achieving tight glycemic control through intensive insulin therapy and modern insulin regimens is challenging because of the barrier of hypoglycemia, the most feared complication of insulin therapy as reported by patients, caregivers, and physicians. This article outlines the individual components of the closed-loop system together with the existing clinical evidence. The artificial pancreas prototypes currently used in clinical studies are reviewed as well as obstacles and limitations facing the technology.
Le texte complet de cet article est disponible en PDF.Keywords : Closed loop, Continuous glucose sensor, Insulin pump, Algorithm
Plan
| Funding support: Juvenile Diabetes Research Foundation, National Institute of Diabetes and Digestive and Kidney Diseases, NIHR Cambridge Biomedical Research Centre, Medical Research Council Centre for Obesity and Related Metabolic Diseases, Diabetes UK, European Commission Framework Program 7. |
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| Conflicts of interest: R.H. reports having received speaker honoraria from Minimed Medtronic, Lifescan, and Novo Nordisk; serving on advisory panel for Animas and Minimed Medtronic; receiving license fees from BBraun and Becton Dickinson; and having served as a consultant to Becton Dickinson, BBraun, and Profil. H.T. has no competing interests. |
Vol 41 - N° 1
P. 105-117 - mars 2012 Retour au numéro
Article précédent
- Intensive Insulin Therapy in Patients with Type 1 Diabetes Mellitus
- Sean M. Switzer, Emily G. Moser, Briana E. Rockler, Satish K. Garg
- Insulin Therapy in Type 2 Diabetes Mellitus
- Jack L. Leahy
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