Respiratory Physiology During Sleep - 05/09/12
, Daniel Smith, MD, Teofilo Lee-Chiong, MD
Corresponding author. Section of Sleep Medicine, Division of Critical Care and Hospital Medicine, National Jewish Health, 1400 Jackson Street, M323, Denver, CO 80206.Résumé |
The respiratory system provides continuous homeostasis of partial pressures of arterial oxygen, carbon dioxide, and pH levels during constantly changing physiologic conditions. This system responds promptly to subtle variations in metabolism. Modifications occur in the regulation and control of respiration with the onset of sleep, which differ with specific sleep stages. These alterations can lead to sleep-related breathing disorders and limit the usual respiratory compensatory changes to specific disease states. This article reviews the normal physiology of respiration in both awake and sleep states, and discusses the effects of common disease processes and medications on the respiratory physiology of sleep.
Le texte complet de cet article est disponible en PDF.Keywords : Ventilatory regulation, Respiratory motoneurons, Hypoxemia, Hypercapnia, Pneumotaxic center, Apneustic center, Chemoreceptors
Plan
| A version of this article originally appeared in Sleep Medicine Clinics Volume 5, Issue 2. |
Vol 7 - N° 3
P. 497-505 - septembre 2012 Retour au numéro
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