Cushing Syndrome in Pediatrics - 24/10/12
Pediatric Endocrinology Training Program, National Institute of Child Health and Human Development, National Institutes of Health, Building 10, CRC, Room 1–3330 East Laboratories, 10 Center Drive, Bethesda, MD 20892.Résumé |
Cushing syndrome is characterized by truncal obesity, growth deceleration, skin changes, muscle weakness, and hypertension. Cushing syndrome in childhood usually results from the exogenous administration of glucocorticoids. This article presents the causes and discusses the treatment of endogenous Cushing syndrome. It also discusses the clinical and molecular genetics of inherited forms of this syndrome. Cushing syndrome needs to be diagnosed and treated properly when first recognized; improper treatment can turn this otherwise completely curable disorder into a chronic ailment. Barriers to optimal care of a pediatric patient with Cushing syndrome are discussed.
Le texte complet de cet article est disponible en PDF.Keywords : Cushing syndrome, Pituitary tumors, Cortisol, Adrenal cortex, Carney complex, Adrenocortical hyperplasia, Adrenal cancer
Plan
| This work was completed with support by the Intramural Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892–1862. |
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| The author has nothing to disclose. |
Vol 41 - N° 4
P. 793-803 - décembre 2012 Retour au numéro
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