Insight in schizophrenia–course and predictors during the acute treatment phase of patients suffering from a schizophrenia spectrum disorder - 30/10/12
, S. Meyer b, F. Seemüller a, M. Jäger a, M. Schmauss b, G. Laux c, H. Pfeiffer d, D. Naber e, L.G. Schmidt f, W. Gaebel g, J. Klosterkötter h, I. Heuser i, W. Maier j, M.R. Lemke k, E. Rüther l, S. Klingberg m, M. Gastpar n, H.-J. Möller a, M. Riedel a, o
Corresponding author. Tel.: +49 89 5160 5511; fax: +49 89 5160 5728.Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
| pages | 9 |
| Iconographies | 4 |
| Vidéos | 0 |
| Autres | 0 |
Abstract |
Background |
To analyse insight of illness during the course of inpatient treatment, and to identify influencing factors and predictors of insight.
Methods |
Insight into illness was examined in 399 patients using the item G12 of the Positive and Negative Syndrome Scale (“lack of insight and judgement”). Ratings of the PANSS, HAMD, UKU, GAF, SOFAS, SWN-K and Kemp’s compliance scale were performed and examined regarding their potential association with insight. The item G12 was kept as an ordinal variable to compare insight between subgroups of patients.
Results |
Almost 70% of patients had deficits in their insight into illness at admission. A significant improvement of impairments of insight during the treatment (p<0.0001) was observed. At admission more severe positive and negative symptoms, worse functioning and worse adherence were significantly associated with poorer insight. Less depressive symptoms (p=0.0004), less suicidality (p=0.0218), suffering from multiple illness-episodes (p<0.0001) and worse adherence (p=0.0012) at admission were identified to be significant predictors of poor insight at discharge.
Conclusion |
The revealed predictors might function as treatment targets in order to improve insight and with it outcome of schizophrenia.
Le texte complet de cet article est disponible en PDF.Keywords : Insight, Schizophrenia, Course, Predictors, Outcome
Plan
Vol 27 - N° 8
P. 625-633 - novembre 2012 Retour au numéro
Article précédent
- The association between insight and symptoms in bipolar inpatients: An Italian prospective study
- C. Bressi, M. Porcellana, P.M. Marinaccio, E.P. Nocito, M. Ciabatti, L. Magri, A.C. Altamura
- Corrigendum to “European Psychiatric Association guidance on the conflicts of interest” [Eur Psychiatry 2012;27:142–6]
- C. Höschl, L. Fialová
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’achat d’article à l’unité est indisponible à l’heure actuelle.
Déjà abonné à cette revue ?