Benign neoplasms of the skin are commonly seen by all physicians. It is vital to distinguish these proliferations from malignant lesions. Despite their benign nature, many of these neoplasms cause aesthetic or symptomatic distress and require removal. Some of these benign neoplasms may serve as markers for internal disease or genetic syndromes. Multiple forms of therapy, including excision, cryotherapy, curettage, laser therapy, and pharmacotherapy, are available. This article discusses the epidemiology, clinical presentation, and recent advances in the management of these benign lesions.