Lactoferrin and Necrotizing Enterocolitis - 13/02/13
Résumé |
Lactoferrin (LF) is a multifunctional protein and a member of the transferrin family. LF and lysozyme in breast milk kill bacteria. In the stomach, pepsin digests and releases a potent peptide antibiotic called lactoferricin from native LF. The antimicrobial characteristics of LF may facilitate a healthy intestinal microbiome. LF is the major whey in human milk; its highest concentration is in colostrum. This fact highlights early feeding of colostrum and also fresh mature milk as a way to prevent necrotizing enterocolitis.
Le texte complet de cet article est disponible en PDF.Keywords : Lactoferrin, Necrotizing enterocolitis, Prophylaxis, Intelectin, Toll-like receptors, Endotoxin binding, Dendritic cells, Th1 cells
Plan
| Funding: This work was supported in part by NIH grant HD057744 and a Gerber Foundation grant. |
Vol 40 - N° 1
P. 79-91 - mars 2013 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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