In vitro study assessing the antibacterial activity of three silver-impregnated/coated mechanical valve needleless connectors after blood exposure - 26/02/13
, Jennifer L. Waller, PhD b, William R. Jarvis, MD c
Address correspondence to Cynthia C. Chernecky, RN, PhD, AOCN, FAAN, Department of Physiological and Technological Nursing, Georgia Health Sciences University, College of Nursing, 120 15th Street, EC 5509, Augusta, GA 30912.Abstract |
This in vitro study’s purpose was to assess antibacterial activity of 3 different connectors: V-Link (Baxter, Deerfield, IL), Ultrasite Ag (B. Braun, Bethlehem, PA), and MaxGuard (CareFusion, Ontario, CA), impregnated with silver nanoparticles after blood exposure. All 3 silver-coated/impregnated connectors grew Staphylococcus aureus and Staphylococcus epidermidis. Log reduction of bacteria was not significant (range, +0.19 to −1.82). There was substantial bacterial recovery from all 3 connectors (mean ranges, 2.09 × 107 to 4.00 × 108) indicating that, once blood comes in contact with silver-coated/impregnated needleless connectors, their antibacterial activity is significantly reduced.
Le texte complet de cet article est disponible en PDF.Key Words : Intravenous, Bacteremia, Bloodstream infections, Central line-associated bloodstream infections
Plan
| The laboratory testing was funded by RyMed Technologies, Inc (Franklin, TN), and conducted by an independent laboratory, Nelson Laboratories, Inc, Salt Lake City, UT. All protocols and test data were supplied directly to the authors. No data were omitted or modified. RyMed purchased and supplied the sterile test needleless connectors for testing to Nelson Laboratories, Inc. All products were obtained from the marketplace and were not modified or manipulated in any manner before the testing. None of the authors received any funding for preparation of this manuscript. |
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| Conflicts of interest: C.C.C., J.L.W., and W.R.J. analyzed the complete data set and wrote the manuscript. They received no compensation for preparation of this manuscript from RyMed Technologies, Inc. C.C.C. has been a consultant for Bard and RyMed Technologies, Inc, in the past 3 years. W.R.J. has been a consultant for Bard, Becton-Dickinson, Johnson and Johnson, Excelsiour, and BD in the past 3 years. J.L.W. has been a consultant for RyMed Technologies, Inc, in the past 3 years. |
Vol 41 - N° 3
P. 278-280 - mars 2013 Retour au numéro
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