The spatial sampling offered by TOPEX and Jason series of satellite radar altimeters and its continuity during the last twenty years are major assets to provide an improved vision of the global mean sea level (GMSL). The objective of this paper is to examine the recent GMSL variations (1993–2012) and to investigate the correlation between the GMSL and ENSO (El Niño-southern oscillation) episodes. For this purpose, a mean sea level anomalies time series, obtained from TOPEX, Jason-1 and Jason-2 measurements, is used to determine the trend of GMSL changes by using a simplified form of an unobserved components model (namely UCM). Then, to investigate the impact of the ENSO phenomenon on the GMSL changes, we considered the sea surface temperature anomalies (SSTA) index over the Niño3 region (5N–5S 150W–90W). Cross wavelet transform and wavelet coherence analysis are performed to expose common power between the GMSL changes and the SSTA index and their relative phase in the time–frequency space. The results indicate that there are in the estimated GMSL's trend a number of fluctuations over short periods that are least partly related to the El Niño/La Niña episodes. Cross wavelet transform and wavelet coherence analysis indicate that a significant correlation between GMSL and ENSO occurred during 1997–1998, 2006–2007, 2009–2010 El Niño events and 2007–2008 and 2010–2011 La Niña ones. All these areas show in-phase relationship, suggesting that GMSL and SSTA index vary synchronously.