2629 – Impaired emotional processing is reflected in long latency event related potentials during visual emotional stimulation in post-traumatic patients - 09/07/13
Résumé |
Introduction |
PTSD patients display abnormal emotional processing and bias towards negative emotion. Long latency eventrelated potentials (ERP’s) are composed of the P300 and subsequent slow wave activity. These ERP’s are hypothesized to be relevant for attentional and initial memory storage events as well as emotional processing. objectives: This study tested the hypothesis that abnormal emotional processing in PTSD is reflected in altered brain activity, as measured via ERP’s.
Aims |
Detect differences in cortical activity and emotional processing in PTSD patients as compared to controls.
Methods |
ERP’s were recorded from 14 PTSD and 14 control subjects while viewing emotion-laden pictures. Subjects were instructed to press a button depending on the presence of a person or human part in the picture and response time was recorded.
Results |
Long latency ERP data (300-1035 msec) showed valence dependent activity in control subjects distinguishing negative vs. positive and neutral pictures. PTSD patients, however, lacked differential activation and had similar brain activity across all picture valances, which resembled the pattern observed in controls only for negative stimuli.
[Late ERP’s 980-1035msec]
[Late ERP’s 980-1035msec]
PTSD patients also exhibited longer response time.
Conclusions |
Our results demonstrate abnormal cognitive-emotional processing in PTSD patients and may underlie overgeneralization processes that are part of this disorder.
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Vol 28 - N° S1
P. 1 - 2013 Retour au numéro
Article précédent
- 2628 – Prevalence and characteristics of adult attention-deficit hyperactivity disorder among substance use inpatients
- A. Abdelkarim, H. Salama, S. Abdel Latif, O. Abou El Magd
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- L. Spattini, A. Ghidoni, E. Simoni, G. Landi, C. Visentini, L. Pingani, A. Boenink, S. Ferrari, G. Mattei
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