Case Selection for Cardiac Resynchronization in Atrial Fibrillation - 20/09/13
, Freidoon Keshavarzi, MD, MRCP, Pierpaolo Pellicori, MD, Benjamin Dicken, MBBS, MRCPRésumé |
Remarkably little evidence exists that cardiac resynchronization therapy (CRT) is effective in patients who have atrial fibrillation (AF) but who otherwise seem suitable for this treatment. The landmark trials of CRT generally excluded patients with AF because atrioventricular (AV) resynchronization was considered a possibly important mechanism by which CRT might deliver its benefits. The only landmark trial that included many patients with AF confirmed marked benefit among patients in sinus rhythm but no benefit among those with AF. Evidence is lacking that biventricular rather than AV resynchronization is an important mechanism for delivering the benefits of CRT.
Le texte complet de cet article est disponible en PDF.Keywords : Cardiac resynchronization therapy, Atrial fibrillation, Atrioventricular resynchronization, Biventricular capture, Heart failure
Plan
| Disclosures: Professor Cleland has received honoraria from Medtronic, Sorin and St Jude within the last 5 years for speaking at symposia and on advisory committees. Prof Cleland and Dr Dicken are investigators for the RESPOND study, funded by Sorin. |
Vol 9 - N° 4
P. 461-474 - octobre 2013 Retour au numéro
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- Atrial Fibrillation in Heart Failure in the Older Population
- Patrick M. Heck, Justin M.S. Lee, Peter M. Kistler
- Cardiac Resynchronization Therapy Mechanisms in Atrial Fibrillation
- Zachary I. Whinnett, Darrel P. Francis
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