Vancomycin-resistant enterococci colonization does not increase mortality in end-stage kidney failure: a case–control study - 08/11/13
, K.R. Polkinghorne b, c, D. Kotsanas a, P.G. Kerr b, c, T.M. Korman a, c, R.L. Stuart a, cSummary |
Background |
Vancomycin-resistant enterococci (VRE) colonization is a frequent occurrence in patients with renal failure. Understanding the impact of VRE colonization on this group of patients has considerable clinical applicability.
Aim |
To understand whether VRE colonization in renal patients has an impact on number of admissions to hospital, length of stay, and mortality.
Methods |
A retrospective case–control study of renal dialysis patients was performed between 2000 and 2010. Cases were 134 VRE-colonized patients requiring renal replacement therapy and matched controls were 137 non-colonized patients with the same baseline characteristics. Matched cases and controls were analysed for differences in number of admissions, length of stay, and mortality.
Findings |
There was no difference in mortality between colonized and non-colonized patients (hazard ratio: 1.14; 95% confidence interval: 0.78–1.69; P = 0.49). Length of stay for colonized patients was 7.29 days compared with 4.14 days (P < 0.001). The number of admissions for VRE-colonized patients was not significantly different compared with controls (9.34 vs 8.33, P = 0.78).
Conclusion |
VRE colonization did not increase mortality in renal patients but did contribute to increased length of stay.
Le texte complet de cet article est disponible en PDF.Keywords : Colonization, Dialysis, Renal, Vancomycin-resistant enterococci
Plan
Vol 85 - N° 4
P. 289-296 - décembre 2013 Retour au numéro
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