Clonal Relationships Between Malignant Lymphomas and Histiocytic/Dendritic Cell Tumors - 17/11/13
Abstract |
Tumors of histiocytic or dendritic cell origin appear to occur with increased frequency in patients with lymphoma. Recent molecular data have demonstrated clonal relationships between the lymphoma and the histiocytic/dendritic cell tumor in some of these cases. Clinical, pathologic, and experimental data suggest that this phenomenon probably represents transdifferentiation of the lymphoma clone to a histiocytic/dendritic cell lineage in most cases. Awareness of this entity is necessary to prompt comparative molecular studies in appropriate cases.
Le texte complet de cet article est disponible en PDF.Keywords : Transdifferentiation, Histiocytic sarcoma, Dendritic cell tumor, Langerhans cell histiocytosis, Transformation, Lineage plasticity, Clonality
Plan
| Disclosures: None. |
Vol 6 - N° 4
P. 619-629 - décembre 2013 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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