COPD : Definition and Phenotypes - 06/02/14
Résumé |
Chronic obstructive pulmonary disease (COPD) is currently defined as a common preventable and treatable disease that is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases. Exacerbations and comorbidities contribute to the overall severity in individual patients. The evolution of this definition and the diagnostic criteria currently in use are discussed. COPD is increasingly divided in subgroups or phenotypes based on specific features and association with prognosis or response to therapy, the most notable being the feature of frequent exacerbations.
Le texte complet de cet article est disponible en PDF.Keywords : COPD, Definition, Diagnosis, Lung function, Chronic inflammation
Plan
| Disclosure of Interests: J. Vestbo has received honoraria for advising Bioxydyn, Chiesi, GlaxoSmithKline, Novartis, Syntaxin, and Takeda. J. Vestbo has received honoraria for presenting from AstraZeneca, Boehringer-Ingelheim, Chiesi, GlaxoSmithKline, Novartis, and Takeda. J. Vestbo is a member (vice-chair) of the Board of Directors of the Global Initiative for Obstructive Lung Diseases (GOLD), and he is the chair of the GOLD Scientific Committee. |
Vol 35 - N° 1
P. 1-6 - mars 2014 Retour au numéro
Article précédent
- Chronic Obstructive Pulmonary Disease
- Peter J. Barnes
- Epidemiology and Prevalence of Chronic Obstructive Pulmonary Disease
- Enrique Diaz-Guzman, David M. Mannino
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