Differential Background Clearance of Fluorodeoxyglucose Activity in Normal Tissues and its Clinical Significance - 28/03/14
, Abass Alavi b, Nam Ju Lee, MD b, Scott R. Akers, MD, PhD aRésumé |
The clearance of 2-deoxy-2-[18F]fluoro-d-glucose (FDG) activity in normal tissues varies significantly with extended distribution time. Although most tissues have lower standardized uptake value (SUV) on 2-hour/3-hour delayed images, others may have stable or higher FDG activity with longer distribution times. The continuously decreased SUV on delayed imaging in some tissues, especially in the liver, indicates that longer distribution time will decrease background activity, increase lesion-to-background ratio, and thus improve imaging quality, whereas the continuously increased SUV from 1to 3 hours in the heart suggest that longer distribution time will improve detection of viable myocardium in a viability study.
Le texte complet de cet article est disponible en PDF.Keywords : Fluorodeoxyglucose, PET, SUV, Distribution time, Background activity, Delayed imaging
Plan
| This study was supported in part by a pilot grant from the Department of Veterans Affairs (VISN 4 CPPF Grant). The content of this article does not necessarily reflect the views of the US Department of Veterans Affairs or of the US Government. |
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| Conflict of interest: None. |
Vol 9 - N° 2
P. 209-216 - avril 2014 Retour au numéro
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