Correlates of self-reported quality of life in adults and children with morphea - 16/04/14
Abstract |
Background |
Determining a disease's impact on life quality is important in clinical decision making, research, and resource allocation. Determinants of quality of life (QOL) in morphea are poorly understood.
Objective |
We sought to ascertain demographic and clinical variables correlated with negative impact on self-reported QOL in morphea.
Methods |
We conducted a cross-sectional survey of the Morphea in Adults and Children cohort.
Results |
Symptoms (pruritus and pain) and functional impairment were correlated with decreased QOL in children and adults. This was true in both sexes and was independent of subtype and age. Patient-reported QOL correlated with physician-based measures of disease severity in adults, but not in children. Patients with linear and generalized morphea had the greatest impact on QOL.
Limitations |
Small sample size is a limitation.
Conclusion |
Symptoms and functional impairment were determinants of impaired life quality in both children and adults independent of morphea subtype. These results suggest that clinicians should consider suppressing the accumulation of new lesions (when rapidly accumulating) and symptoms (pain and pruritus) in the treatment of patients with morphea.
Le texte complet de cet article est disponible en PDF.Key words : life quality or quality of life, localized scleroderma, morphea, Morphea in Adults and Children cohort, outcomes or disease outcomes
Abbreviations used : CDLQI, DLQI, LoSCAT, MAC, mRSS, QOL
Plan
Research for this article was supported by National Institutes of Health (NIH) Grant No. K23AR056303-4. This work was conducted with support from UT-STAR, NIH/National Center for Research Resources (NCRR)/National Center for Advancing Translational Sciences (NCATS) Grant No. UL1RR024982. The content is solely the responsibility of the authors and does not necessarily represent the official views of UT-STAR, the University of Texas Southwestern Medical Center at Dallas and its affiliated academic and health care centers, the NCRR, or the NIH. |
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Conflicts of interest: None declared. |
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Reprints not available from the authors. |
Vol 70 - N° 5
P. 904-910 - mai 2014 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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