School-Age Outcomes following a Randomized Controlled Trial of Magnesium Sulfate for Neuroprotection of Preterm Infants - 22/07/14
Doi : 10.1016/j.jpeds.2014.04.007
Clément Chollat, MD 1, 2, ⁎ 
, Maya Enser, MD 3, Estelle Houivet, MSc 4, Delphine Provost, MD 3, Jacques Bénichou, MD, PhD 4, Loïc Marpeau, MD 2, 5, Stéphane Marret, MD, PhD 1, 2
, Maya Enser, MD 3, Estelle Houivet, MSc 4, Delphine Provost, MD 3, Jacques Bénichou, MD, PhD 4, Loïc Marpeau, MD 2, 5, Stéphane Marret, MD, PhD 1, 2 1 Department of Neonatal Pediatrics and Intensive Care, Rouen University Hospital, Rouen, France
2 Region INSERM Team 28 “NeoVasc”, Laboratory of Microvascular Endothelium and Neonate Brain Lesions, Institute for Biomedical Research, Rouen University, Rouen, France
3 Department of Anesthetics and Intensive Care, Rouen University Hospital, Rouen, France
4 Department of Biostatistics, Rouen University Hospital, Rouen, France
5 Department of Obstetrics and Gynecology, Rouen University Hospital, Rouen, France
∗Reprint requests: Clément Chollat, MD, Hôpital Charles Nicolle Service de Pédiatrie Néonatale et Réanimation, 1 rue de Germont, 76000 Rouen, France.
Abstract |
In a French randomized trial, children at school-age demonstrated no evidence of harm from fetal exposure to MgSO4 before very preterm birth. Motor dysfunction/death, qualitative behavioral disorders, cognitive difficulties, school grade repetition, and education services were decreased in the children exposed to MgSO4, although the differences were not significant.
Le texte complet de cet article est disponible en PDF.Keyword : CP, SDQ
Plan
| This follow-up study was funded by the European Regional Development Fund and the Upper-Normandy region. The authors declare no conflicts of interest. |
|
| Registered with ClinicalTrials.gov: NCT00120588. |
© 2014
Elsevier Inc. Tous droits réservés.
Vol 165 - N° 2
P. 398 - août 2014 Retour au numéro
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