Validation study of a modern treatment algorithm for nipple discharge - 26/07/14
Abstract |
Background |
Nipple discharge occurs in 2% to 5% of women. We evaluated the effectiveness of a previously proposed treatment algorithm for these patients.
Methods |
Patients with pathologic nipple discharge and a negative mammogram and subareolar ultrasound were offered follow-up from 2005 to 2011 according to the algorithm.
Results |
A total of 192 patients, mean age 56 years, were studied. Risk of carcinoma among the entire cohort was 5%. Breast surgeon was consulted for 142 (74%) patients: 48 (34%) underwent initial subareolar excision and 94 (66%) were clinically followed. The rate of carcinoma was 17% (8/48) after initial subareolar excision, 0% (0/13) for those without imaging abnormalities, 23% (8/35) with imaging abnormalities, and 1% (1/94) with clinical follow-up. Of patients who underwent follow-up, 21% (n = 20) underwent subareolar excision because of imaging abnormality (n = 1, 1%) or persistent discharge (n = 19, 20%). Most patients had ductal carcinoma in situ (n = 5, 56%).
Conclusions |
Patients with nipple discharge can be prospectively identified based on radiographic findings and clinical examination for safe clinical follow-up. Most will have resolution avoiding a surgical procedure.
Le texte complet de cet article est disponible en PDF.Keywords : Breast cancer, Nipple discharge, Treatment algorithm, Validation study
Plan
| There were no relevant financial relationships or any sources of support in the form of grants, equipment, or drugs. |
|
| The authors declare no conflicts of interest. |
Vol 208 - N° 2
P. 222-227 - août 2014 Retour au numéro
Article précédent
- Increased risk of thromboembolism in esophageal cancer patients treated with neoadjuvant chemoradiotherapy
- Dirk J. Bosch, Quirine A. Van Dalfsen, Véronique E.M. Mul, Geke A.P. Hospers, John Th.M. Plukker
- p27 expression in post-treatment rectal cancer: a potential novel approach for predicting residual nodal disease
- Tobias Leibold, Vanessa W. Hui, Jinru Shia, Jeannine A. Ruby, Elyn R. Riedel, José G. Guillem
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?