Assessing Biological Aggression in Adrenocortical Neoplasia - 08/11/14

Abstract |
Pathologists are highly skilled at the evaluation of adrenal neoplasms. Occasional adrenocortical tumors can be diagnostically challenging and supplementary tools can assist in these cases. Histologic and molecular studies support a model that includes 2 broad classes of adrenocortical carcinoma with distinct somatic genetic alterations and clinical outcomes. Pathologists should endeavor to grade adrenocortical carcinomas to assign each case into one of these 2 classes. Mitotic grading by mitotic counting and Ki-67 immunohistochemistry represent the most practicable and informative methods currently available.
Le texte complet de cet article est disponible en PDF.Keywords : Adrenocortical neoplasia, Adrenocortical adenomas, Adrenocortical carcinomas, Histologic grading, Molecular grading
Plan
Vol 7 - N° 4
P. 533-541 - décembre 2014 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?
