Chorioamnionitis : Implications for the Neonate - 11/02/15
Résumé |
Chorioamnionitis (CA) is characterized by inflammation of the fetal membranes. The incidence increases with decreasing gestational age at birth. When suspected on clinical criteria, pathologic assessment of the placenta should be performed. Although the mechanisms are not entirely clear, CA predisposes to premature birth, neonatal sepsis, and intraventricular hemorrhage. Its role in respiratory distress syndrome, bronchopulmonary dysplasia, and neurodevelopmental impairment is mixed. Prevention and treatment are ill-defined; antibiotics for preterm premature rupture of membranes reduce the incidence and increase the length of time to delivery. Antibiotics are recommended for infants exposed to CA while laboratory studies are being performed.
Le texte complet de cet article est disponible en PDF.Keywords : Neonatal sepsis, Fetal inflammatory response, Mycoplasma
Plan
| Dr M.M. Laughon receives support from the U.S. government for his work in pediatric and neonatal clinical pharmacology (Government Contract HHSN267200700051C, PI: Benjamin under the Best Pharmaceuticals for Children Act) and from National Institute of Child Health and Human Development (K23HD068497). Dr J.E. Ericson receives support from the National Institute of Child Health and Human Development of the National Institutes of Health under award number 5T32HD060558. |
Vol 42 - N° 1
P. 155-165 - mars 2015 Retour au numéro
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