Gastric bypass improves survival compared with propensity-matched controls: a cohort study with over 10-year follow-up - 13/03/15
, Stephen W. Davies, M.D., M.P.H., Robert G. Sawyer, M.D., Bruce D. Schirmer, M.D., Peter T. Hallowell, M.D.Abstract |
Background |
The purpose of this study is to evaluate the long-term survival following gastric bypass using propensity-matched controls.
Methods |
We identified all patients who either received a gastric bypass (GBP) or met criteria to receive a GBP between January 1, 2002 and December 31, 2003. Propensity matching was performed. Long-term, all-cause mortality data were collected and evaluated using Kaplan–Meier curves.
Results |
Four hundred thirty GBP cases and 5,323 controls were identified from the enrollment period. Ultimately, 802 cases and controls (1:1 matching, 93.2% match rate) were identified using propensity matching. Median follow-up was similar between groups. Overall mortality was lower for the GBP group (odds ratio .48, 95% confidence interval .29 to .78). GBP demonstrated significantly increased survival when compared with controls (P = .002). Similar patterns were noted among diabetics.
Conclusion |
We have demonstrated that gastric bypass provides a clear long-term survival advantage compared with nonsurgical propensity-matched controls.
Le texte complet de cet article est disponible en PDF.Keywords : Obesity, Survival, Gastric bypass, Propensity
Plan
| This work was funded by a National Institutes of Health training grant (T32 AI078875). The funding source had no involvement in any part of this study. |
Vol 209 - N° 3
P. 463-467 - mars 2015 Retour au numéro
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