Immunologic basis for allopurinol-induced severe cutaneous adverse reactions: HLA-B*58:01-restricted activation of drug-specific T cells and molecular interaction - 03/04/15

Chia-Hsien Lin, MS ^{a, b}, Jung-Kuei Chen, MS ^b, Tai-Ming Ko, PhD ^b, Chun-Yu Wei, PhD ^b, Jer-Yuarn Wu, PhD ^b, Wen-Hung Chung, MD, PhD ^e, Shih-Yang Chen, MD ^f, You-Di Liao, PhD ^b, Shuen-Iu Hung, PhD ^{c, d} , Yuan-Tsong Chen, MD, PhD ^{a, b}

^a Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan 

^b Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan 

^c Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan 

^d Infection and Immunity Research Center, National Yang-Ming University, Taipei, Taiwan 

^e Department of Dermatology, Chang Gung Memorial Hospital, Taipei, Taiwan 

^f Center of Gout, Country Hospital, Taipei, Taiwan