Update and Commentary on Four Emerging Tick-Borne Infections : Ehrlichia muris–like Agent, Borrelia miyamotoi, Deer Tick Virus, Heartland Virus, and Whether Ticks Play a Role in Transmission of Bartonella henselae - 20/05/15

Doi : 10.1016/j.idc.2015.02.009

Gary P. Wormser, MD ^a,^⁎ , Bobbi Pritt, MD, MSc, DTM&H ^b
^a Division of Infectious Diseases, New York Medical College, 40 Sunshine Cottage Road, Skyline Office #2N-C20, Valhalla, NY 10595, USA
^b Division of Clinical Microbiology, Department of Pathology and Laboratory Medicine, Mayo Clinic, 200 1st Street, SW, Rochester, MN 55905, USA

^∗Corresponding author.

Résumé

Emerging tick-borne infections continue to be observed in the United States and elsewhere. Current information on the epidemiology, clinical and laboratory features, and treatment of infections due to Ehrlichia muris–like agent, deer tick virus, Borrelia miyamotoi sensu lato, and Heartland virus is provided and critically reviewed. More research is needed to define the incidence and to understand the clinical and the laboratory features of these infections. There is also a growing need for the development of sensitive and specific serologic and molecular assays for these infections that are easily accessible to clinicians.

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Keywords : Tick-transmitted infections, Ehrlichia, Borrelia, Deer tick virus, Powassan virus, Heartland virus, Bartonella

Plan

Key points

Introduction

Ehrlichia muris–like agent

Disclosures: Dr G.P. Wormser reports receiving research grants from Immunetics, Inc, RareCyte, Inc, Institute for Systems Biology and bioMérieux SA. He owns equity in Abbott; has been an expert witness in malpractice cases involving Lyme disease; is an unpaid board member of the American Lyme Disease Foundation; has been an expert witness regarding Lyme disease in a disciplinary action for the Missouri Board of Registration for the Healing Arts; and was a consultant to Baxter for Lyme disease vaccine development. Dr B. Pritt reports receiving a research grant from the Minnesota Partnership for Biotechnology and Medical Genomics for malaria research. She is an unpaid board member for the College of American Pathologists Microbiology Resource Committee and receives a reviewer’s stipend from the Journal of Clinical Microbiology.