Complement : An Overview for the Clinician - 30/05/15

Résumé |
The complement system is an essential component of the immune system. It is a highly integrative system and has a number of functions, including host defense, removal of injured cells and debris, modulation of metabolic and regenerative processes, and regulation of adaptive immunity. Complement is activated via different pathways and it is regulated tightly by several mechanisms to prevent host injury. Imbalance between complement activation and regulation can manifest in disease and injury to self. This article provides an outline of complement activation pathways, regulatory mechanisms, and normal physiologic functions of the system.
Le texte complet de cet article est disponible en PDF.Keywords : Complement system, Complement activation, Complement regulation, Complement function, Inflammation, Immune response
Plan
| The authors have nothing to disclose. |
Vol 29 - N° 3
P. 409-427 - juin 2015 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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