Closed loop insulin delivery in diabetes - 06/06/15
, Jasna Šuput Omladič, M.D. a, Moshe Phillip, M.D. c, d : DirectorAbstract |
The primary goal of type 1 diabetes treatment is attaining near-normal glucose values. This currently remains out of reach for most people with type 1 diabetes despite intensified insulin treatment in the form of insulin analogues, educational interventions, continuous glucose monitoring, and sensor augmented insulin pump. The main remaining problem is risk of hypoglycaemia, which cannot be sufficiently reduced in all patient groups. Additionally, patients' burn-out often develops with years of tedious day-to-day diabetes management, rendering available diabetes-related technology less efficient. Over the past 40 years, several attempts have been made towards computer-programmed insulin delivery in the form of closed loop, with faster developments especially in the past decade. Automated insulin delivery has reduced human error in glycaemic control and considerably lessened the burden of routine self-management. In this chapter, data from randomized controlled trials with closed-loop insulin delivery that included type 1 diabetes population are summarized, and an evidence-based vision for possible routine utilization of closed loop is provided.
Le texte complet de cet article est disponible en PDF.Keywords : closed loop insulin delivery, artificial pancreas, sensor augmented insulin pump, continuous glucose monitoring, hypoglycaemia, glycaemic range, mean blood glucose, glucose variability
Plan
Vol 29 - N° 3
P. 315-325 - juin 2015 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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