Índice

• • ·Editorial Board

    Artículo :116641

    

• Review Articles

  • ·Mechanistic insights into the potential role of dietary polyphenols and their nanoformulation in the management of Alzheimer’s disease

    Artículo :116376

    Hind Muteb Albadrani, Payal Chauhan, Sumel Ashique, M. Arockia Babu, Danish Iqbal, Abdulmajeed G. Almutary, Mosleh Mohammad Abomughaid, Mehnaz Kamal, Ana Cláudia Paiva-Santos, Mohammed Alsaweed, Munerah Hamed, Punya Sachdeva, Saikat Dewanjee, Saurabh Kumar Jha, Shreesh Ojha, Petr Slama, Niraj Kumar Jha

    Resumen Resumen Esquema Esquema  
  • ·Solid lipid nanoparticles and their application in the treatment of bacterial infectious diseases

    Artículo :116433

    Mohammad Reza Arabestani, Ashkan Bigham, Farideh Kamarehei, Mahya Dini, Fatemeh Gorjikhah, Aref Shariati, Seyed Mostafa Hosseini

    Resumen Resumen Esquema Esquema  
  • ·Targeting novel regulated cell death：Ferroptosis, pyroptosis, and autophagy in sepsis-associated encephalopathy

    Artículo :116453

    Jingjing Sun, Joshua S. Fleishman, Xueyan Liu, Hongquan Wang, Liang Huo

    Resumen Resumen Esquema Esquema  
  • ·A new frontier in precision medicine: Exploring the role of extracellular vesicles in chronic obstructive pulmonary disease

    Artículo :116443

    Zixuan Gou, Hongrun Yang, Ruijia Wang, Shihan Wang, Qirui Chen, Ziyu Liu, Ying Zhang

    Resumen Resumen Esquema Esquema  
  • ·Exploring the therapeutic potential of regulatory T cell in rheumatoid arthritis: Insights into subsets, markers, and signaling pathways

    Artículo :116440

    Qin-Yi Su, Huan-Cheng Li, Xiao-Jing Jiang, Zhong-Qing Jiang, Yan Zhang, He-Yi Zhang, Sheng-Xiao Zhang

    Resumen Resumen Esquema Esquema  
  • ·Gut microbiota in neurological diseases: Melatonin plays an important regulatory role

    Artículo :116487

    Somayeh Ahmadi, Mohammad Taghizadieh, Elham Mehdizadehfar, Alka Hasani, Javad Khalili Fard, Hadi Feizi, Hammed Hamishehkar, Masood Ansarin, Mina Yekani, Mohammad Yousef Memar

    Resumen Resumen Esquema Esquema  
  • ·Emerging regulatory mechanisms in cardiovascular disease: Ferroptosis

    Artículo :116457

    Sijie Jin, He Wang, Xiaohao Zhang, Mengyang Song, Bin Liu, Wei Sun

    Resumen Resumen Esquema Esquema  
  • ·Controllers of histone methylation-modifying enzymes in gastrointestinal cancers

    Artículo :116488

    Ling Li, Qing Song, Jing Zhou, Qing Ji

    Resumen Resumen Esquema Esquema  
  • ·The role of miR-155 in urologic malignancies

    Artículo :116412

    Maolei Shen, Tao Chen, Xin Li, Shankun Zhao, Xinsheng Zhang, Liying Zheng, Biao Qian

    Resumen Resumen Esquema Esquema  
  • ·Bioactive compounds from nature: Antioxidants targeting cellular transformation in response to epigenetic perturbations induced by oxidative stress

    Artículo :116432

    Abdelhakim Bouyahya, Saad Bakrim, Sara Aboulaghras, Kawtar El Kadri, Tarik Aanniz, Asaad Khalid, Ashraf N. Abdalla, Ahmed A. Abdallah, Chrismawan Ardianto, Long Chiau Ming, Nasreddine El Omari

    Resumen Resumen Esquema Esquema  
  • ·Growth and differentiation factor-15: A link between inflammaging and cardiovascular disease

    Artículo :116475

    Balázs Bence Nyárády, Loretta Zsuzsa Kiss, Zsolt Bagyura, Béla Merkely, Edit Dósa, Orsolya Láng, László Kőhidai, Éva Pállinger

    Resumen Resumen Esquema Esquema  
  • ·Research progress on Sirtuins (SIRTs) family modulators

    Artículo :116481

    Mingkai Chen, Junfei Tan, Zihan Jin, Tingting Jiang, Jiabiao Wu, Xiaolong Yu

    Resumen Resumen Esquema Esquema  
  • ·Demethylases in tumors and the tumor microenvironment: Key modifiers of N⁶-methyladenosine methylation

    Artículo :116479

    Junchen Guo, Liang Zhao, Meiqi Duan, Zhi Yang, He Zhao, Baiming Liu, Yihan Wang, Liping Deng, Chen Wang, Xiaodi Jiang, Xiaofeng Jiang

    Resumen Resumen Esquema Esquema   
  • ·Antioxidants activities of phytochemicals perspective modulation of autophagy and apoptosis to treating cancer

    Artículo :116497

    Kazi Rejvee Ahmed, Md. Masudur Rahman, Md. Nahidul Islam, Md. Maharub Hossain Fahim, Md Ataur Rahman, Bonglee Kim

    Resumen Resumen Esquema Esquema  
  • ·Implementation of antibody-drug conjugates in HER2-positive solid cancers: Recent advances and future directions

    Artículo :116522

    Jiazheng Yu, Mingyang Li, Xiandong Liu, Siyu Wu, Rong Li, Yuanhong Jiang, Jianyi Zheng, Zeyu Li, Kerong Xin, Zhenqun Xu, Shijie Li, Xiaonan Chen

    Resumen Resumen Esquema Esquema  
  • ·The ion channel basis of pharmacological effects of amiodarone on myocardial electrophysiological properties, a comprehensive review

    Artículo :116513

    Illia Gelman, Neelakshi Sharma, Olivia Mckeeman, Peter Lee, Noah Campagna, Nicole Tomei, Adrian Baranchuk, Shetuan Zhang, Mohammad El-Diasty

    Resumen Resumen Esquema Esquema  
  • ·Potential therapeutic applications of circular RNA in acute kidney injury

    Artículo :116502

    Zheng Li, Jihong Xing

    Resumen Resumen Esquema Esquema  
  • ·GPX4, ferroptosis, and diseases

    Artículo :116512

    Wangzheqi Zhang, Yang Liu, Yan Liao, Chenglong Zhu, Zui Zou

    Resumen Resumen Esquema Esquema  
  • ·Efficient combination of radiotherapy and CAR-T – A systematic review

    Artículo :116532

    Wojciech Szlasa, Aleksandra Sztuder, Agnieszka Kaczmar-Dybko, Adam Maciejczyk, Jarosław Dybko

    Resumen Resumen Esquema Esquema  
  • ·Regulation of myogenic cell proliferation and differentiation during mammalian skeletal myogenesis

    Artículo :116563

    Jiyao Wu, Binglin Yue

    Resumen Resumen Esquema Esquema  
  • ·Role of the microbiota–gut–heart axis between bile acids and cardiovascular disease

    Artículo :116567

    Ziyi Zhang, Tingting Lv, Xiang Wang, Menglu Wu, Ruolin Zhang, Xiaopeng Yang, Yongping Fu, Zheng Liu

    Resumen Resumen Esquema Esquema  
  • ·Mechanism of metal ion-induced cell death in gastrointestinal cancer

    Artículo :116574

    Muhua Luan, Zhaotian Feng, Wenshuai Zhu, Yuanxin Xing, Xiaoli Ma, Jingyu Zhu, Yunshan Wang, Yanfei Jia

    Resumen Resumen Esquema Esquema  
  • ·Mechanical stress induced mitochondrial dysfunction in cardiovascular diseases: Novel mechanisms and therapeutic targets

    Artículo :116545

    He Ren, Weiyi Hu, Tao Jiang, Qingping Yao, Yingxin Qi, Kai Huang

    Resumen Resumen Esquema Esquema  
  • ·Roles and mechanisms of copper homeostasis and cuproptosis in osteoarticular diseases

    Artículo :116570

    Juanjuan Han, Jiayi Luo, Cuijing Wang, Leonid Kapilevich, Xin-an Zhang

    Resumen Resumen Esquema Esquema  
  • ·Deciphering mitochondrial dysfunction: Pathophysiological mechanisms in vascular cognitive impairment

    Artículo :116428

    Yuyao He, Tiantian He, Hongpei Li, Wei Chen, Biying Zhong, Yue Wu, Runming Chen, Yuli Hu, Huaping Ma, Bin Wu, Wenyue Hu, Zhenyun Han

    Resumen Resumen Esquema Esquema  
  • ·Epigenetic deregulation in breast cancer microenvironment: Implications for tumor progression and therapeutic strategies

    Artículo :116559

    Lenka Trnkova, Verona Buocikova, Michal Mego, Andrea Cumova, Monika Burikova, Martin Bohac, Svetlana Miklikova, Marina Cihova, Bozena Smolkova

    Resumen Resumen Esquema Esquema  
  • ·Recent advances in functional nucleic acid decorated nanomaterials for cancer imaging and therapy

    Artículo :116546

    Liu Wu, Ruitao Yuan, Tong Wen, Yingfeng Qin, Yumin Wang, Xiaoling Luo, Jin-Wen Liu

    Resumen Resumen Esquema Esquema  
  • ·Research status and challenges of plant-derived exosome-like nanoparticles

    Artículo :116543

    Chunmei Bai, Jianrong liu, Xumin Zhang, Yang Li, Qin Qin, Haixia Song, Caixia Yuan, Ziwei Huang

    Resumen Resumen Esquema Esquema  
  • ·Therapeutic vulnerabilities in triple negative breast cancer: Stem-like traits explored within molecular classification

    Artículo :116584

    Peng Huang, Xi Zhang, Jyothi S. Prabhu, Vijay Pandey

    Resumen Resumen Esquema Esquema  
  • ·Tumor extrachromosomal DNA: Biogenesis and recent advances in the field

    Artículo :116588

    Haomin Wu, Shiqi Liu, Di Wu, Haonan Zhou, Gang Wu

    Resumen Resumen Esquema Esquema  
  • ·Elucidating cuproptosis in metabolic dysfunction-associated steatotic liver disease

    Artículo :116585

    Yamei Li, Ping Qi, Si-Yuan Song, Yiping Wang, Hailian Wang, Peng Cao, Yu’e Liu, Yi Wang

    Resumen Resumen Esquema Esquema  
  • ·Role of epigenetics in the regulation of skin aging and geroprotective intervention: A new sight

    Artículo :116592

    Lisa Dal Pozzo, Zhe Xu, Shan Lin, Jida Wang, Ying Wang, Ogbe Susan Enechojo, Joseph Kofi Abankwah, Yanfei Peng, Xiaoqian Chu, Huifang Zhou, Yuhong Bian

    Resumen Resumen Esquema Esquema  
  • ·RETRACTED: Molecular insights into experimental models and therapeutics for cholestasis

    Artículo :116594

    Wenwen Zhang, Hefei Wu, Shiman Luo, Xiaohua Lu, Xiyue Tan, Li Wen, Xiao Ma, Thomas Efferth

    Resumen Resumen
  • ·Advances in liposomes loaded with photoresponse materials for cancer therapy

    Artículo :116586

    Xianwei Zhang, Youfu Ma, Yenong Shi, Lihe Jiang, Lisheng Wang, Haroon ur Rashid, Mingqing Yuan, Xu Liu

    Resumen Resumen Esquema Esquema  
  • ·Progress in the study of molecular mechanisms of intervertebral disc degeneration

    Artículo :116593

    Qiuqiu Xia, Yan Zhao, Huaize Dong, Qiming Mao, Lu Zhu, Jiyue Xia, Zijing Weng, Wenbo Liao, Zongyue Hu, Jiangbi Yi, Shuai Feng, Youhong Jiang, Zhijun Xin

    Resumen Resumen Esquema Esquema  
  • ·Re-exploration of immunotherapy targeting EMT of hepatocellular carcinoma: Starting from the NF-κB pathway

    Artículo :116566

    Shuang Wang, Yan He, Jun Wang, En Luo

    Resumen Resumen Esquema Esquema  
  • ·The novel insights of epithelial-derived exosomes in various fibrotic diseases

    Artículo :116591

    Rifu Wang, Yuxin Shi, Yonglin Lv, Changqing Xie, Yanjia Hu

    Resumen Resumen Esquema Esquema   
  • ·Effects of mitochondrial dysfunction on cellular function: Role in atherosclerosis

    Artículo :116587

    Minwen Xu, Wenjun Wang, Jingpei Cheng, Hongen Qu, Minjuan Xu, Liefeng Wang

    Resumen Resumen Esquema Esquema  
  • ·Construction of preclinical evidence for propofol in the treatment of reperfusion injury after acute myocardial infarction: A systematic review and meta-analysis

    Artículo :116629

    Tao Li, Yanwei Li, Yiwei Zeng, Xin Zhou, Su Zhang, Yulan Ren

    Resumen Resumen Esquema Esquema   
  • ·Tumor-associated carbohydrate antigens of MUC1 – Implication in cancer development

    Artículo :116619

    Iwona Radziejewska

    Resumen Resumen Esquema Esquema  

• Original Articles

  • ·CD19 CAR-expressing iPSC-derived NK cells effectively enhance migration and cytotoxicity into glioblastoma by targeting to the pericytes in tumor microenvironment

    Artículo :116436

    Dasom Kong, Daekee Kwon, Bokyung Moon, Da-Hyun Kim, Min-Ji Kim, Jungju Choi, Kyung-Sun Kang

    Resumen Resumen Esquema Esquema   
  • ·Dexmedetomidine attenuates lipopolysaccharide-induced renal cell fibrotic phenotypic changes by inhibiting necroinflammation via activating α₂-adrenoceptor: A combined randomised animal and in vitro study

    Artículo :116462

    Qizhe Sun, Priyanka Kamath, Yibing Sun, Min Liang, Lingzhi Wu, Enqiang Chang, Qian Chen, Azeem Alam, Yi Liu, Hailin Zhao, Daqing Ma

    Resumen Resumen Esquema Esquema  
  • ·Tolperisone hydrochloride improves motor functions in Parkinson’s disease via MMP-9 inhibition and by downregulating p38 MAPK and ERK1/2 signaling cascade

    Artículo :116438

    Bushra Zaman, Irona Mostafa, Tazree Hassan, Shamim Ahmed, Nusrat Jahan Ikbal Esha, Fowzia Afsana Chowdhury, Tory Bosu, Humayra Noor Chowdhury, Anup Mallick, MM Shanjid Islam, Ayesha Sharmin, Kabir M. Uddin, Md. Mainul Hossain, Mahbubur Rahman

    Resumen Resumen Esquema Esquema   
  • ·Innovative gelatin-based micelles with AS1411 aptamer targeting and reduction responsiveness for doxorubicin delivery in tumor therapy

    Artículo :116446

    Jingmou Yu, Yifei Zhang, Meilin Xu, Dengzhao Jiang, Wenbo Liu, Hongguang Jin, Pu Chen, Jing Xu, Lei Zhang

    Resumen Resumen Esquema Esquema  
  • ·Artificial intelligence-driven drug repositioning uncovers efavirenz as a modulator of α-synuclein propagation: Implications in Parkinson’s disease

    Artículo :116442

    Jae-Bong Kim, Soo-Jeong Kim, Minyoung So, Dong-Kyu Kim, Hye Rin Noh, Beom Jin Kim, Yu Ree Choi, Doyoon Kim, Heejung Koo, Taeyong Kim, Hyun Goo Woo, Sang Myun Park

    Resumen Resumen Esquema Esquema   
  • ·Mebendazole preferentially inhibits cilia formation and exerts anticancer activity by synergistically augmenting DNA damage

    Artículo :116434

    Juyeon Hong, Keun Yeong Kwon, Dong Gil Jang, Taejoon Kwon, Haejin Yoon, Tae Joo Park

    Resumen Resumen Esquema Esquema   
  • ·“Keep on ROCKIn”: Repurposed ROCK inhibitors to boost corneal endothelial regeneration

    Artículo :116435

    Hendrik Vercammen, Martin Ondra, Jana Kotulova, Edgar Cardenas De La Hoz, Charissa Witters, Katerina Jecmenova, Maxim Le Compte, Christophe Deben, Sorcha Ní Dhubhghaill, Carina Koppen, Marián Hajdúch, Bert Van den Bogerd

    Resumen Resumen Esquema Esquema  
  • ·Maximakinin reversed H₂O₂ induced oxidative damage in rat cardiac H9c2 cells through AMPK/Akt and AMPK/ERK1/2 signaling pathways

    Artículo :116489

    Yang Yu, Fan-Fan Su, Cheng Xu

    Resumen Resumen Esquema Esquema   
  • ·Genipin crosslinking promotes biomechanical reinforcement and pro-regenerative macrophage polarization in bioartificial tubular substitutes

    Artículo :116449

    Jone Berasain, Paula Ávila-Fernández, Rocío Cárdenas-Pérez, Antoni Ignasi Cànaves-Llabrés, Miguel Etayo-Escanilla, Miguel Alaminos, Víctor Carriel, Óscar Darío García-García, Jesús Chato-Astrain, Fernando Campos

    Resumen Resumen Esquema Esquema   
  • ·RETRACTED: Inhibition the ubiquitination of ENaC and Na,K-ATPase with erythropoietin promotes alveolar fluid clearance in sepsis-induced acute respiratory distress syndrome

    Artículo :116447

    Ye Gao, Fei Cao, Xinyi Tian, Qianping Zhang, Congcong Xu, Bowen Ji, Ye-an Zhang, Linan Du, Jun Han, Li Li, Siyu Zhou, Yuqiang Gong, Binyu Ying, Fang Gao-Smith, Shengwei Jin

    Resumen Resumen
  • ·Botulinum toxin type A inhibits M1 macrophage polarization by deactivation of JAK2/STAT1 and IκB/NFκB pathway and contributes to scar alleviation in aseptic skin wound healing

    Artículo :116468

    Yan-ping Zou, Xiao-feng Shan, Jia-xuan Qiu, Lin-na Wang, Ruo-lan Xiang, Zhi-gang Cai

    Resumen Resumen Esquema Esquema  
  • ·Senolytic drugs dasatinib and quercetin combined with Carboplatin or Olaparib reduced the peritoneal and adipose tissue metastasis of ovarian cancer

    Artículo :116474

    Lian Wang, Bing Xiong, Wei Lu, Yujie Cheng, Jihui Zhu, Guihai Ai, Xiaojie Zhang, Xiuni Liu, Zhongping Cheng

    Resumen Resumen Esquema Esquema  
  • ·Unlocking the effective alliance of β-lapachone and hydroxytyrosol against triple-negative breast cancer cells

    Artículo :116439

    Jesús Calahorra, José L. Blaya-Cánovas, Olivia Castellini-Pérez, Ernesto Aparicio-Puerta, Candela Cives-Losada, Jose J.G. Marin, Markel Rementeria, Francisca E. Cara, Araceli López-Tejada, Carmen Griñán-Lisón, Francesco Aulicino, Imre Berger, Juan A. Marchal, Violeta Delgado-Almenta, Sergio Granados-Principal

    Resumen Resumen Esquema Esquema   
  • ·Intranasal administration of Escherichia coli Nissle expressing the spike protein of SARS-CoV-2 induces long-term immunization and prevents spike protein-mediated lung injury in mice

    Artículo :116441

    Giovanni Sarnelli, Alessandro Del Re, Irene Palenca, Silvia Basili Franzin, Jie Lu, Luisa Seguella, Aurora Zilli, Marcella Pesce, Sara Rurgo, Giovanni Esposito, Walter Sanseverino, Giuseppe Esposito

    Resumen Resumen Esquema Esquema  
  • ·Utilizing machine learning to identify nifuroxazide as an inhibitor of ubiquitin-specific protease 21 in a drug repositioning strategy

    Artículo :116459

    Jihoon Tak, Tan Khanh Nguyen, Kyeong Lee, Sang Geon Kim, Hee-Chul Ahn

    Resumen Resumen Esquema Esquema   
  • ·The effects of Fc fusion protein glucagon-like peptide-1 and glucagon dual receptor agonist with different receptor selectivity in vivo studies

    Artículo :116485

    Peng Jiang, Ying Zeng, Wen Yang, Lijia Li, Linjun Zhou, Lin Xiao, Yong Li, Baohua Gu, Xiaoping Li, Jing Li, Wenjia Li, Linfeng Guo

    Resumen Resumen Esquema Esquema   
  • ·Resveratrol protects against myocardial ischemic injury in obese mice via activating SIRT3/FOXO3a signaling pathway and restoring redox homeostasis

    Artículo :116476

    Xi Zhu, En Ma, Yixuan Ge, Meng Yuan, Xiaowei Guo, Jun Peng, Weidong Zhu, Dan-ni Ren, Da Wo

    Resumen Resumen Esquema Esquema   
  • ·Targeted inhibition of STAT3 (Tyr705) by xanthatin alleviates osteoarthritis progression through the NF-κB signaling pathway

    Artículo :116451

    Yangjun Xu, Zhuolin Chen, Xuanyuan Lu, Jiewen Zheng, Xuewen Liu, Tan Zhang, Wanlei Yang, Yu Qian

    Resumen Resumen Esquema Esquema   
  • ·Unveil the mechanism for EHMT -- A novel triterpenoid inhibits proliferation and induces apoptosis in colon cancer through ROS-mediated JNK signaling pathway

    Artículo :116469

    Qiushuang Wu, Min Song, Siyuan Luo, Libin Guo, Qingwen Zhang, Hang Fai Kwok

    Resumen Resumen Esquema Esquema   
  • ·Harnessing PD-1 cell membrane-coated paclitaxel dimer nanoparticles for potentiated chemoimmunotherapy

    Artículo :116482

    Nannan Hu, Han Xue, Ting Zhang, Yuxin Fan, Fenglin Guo, Zhimin Li, Mingge Huo, Xingang Guan, Guofu Chen

    Resumen Resumen Esquema Esquema   
  • ·Neuroprotective effects of the salidroside derivative SHPL-49 via the BDNF/TrkB/Gap43 pathway in rats with cerebral ischemia

    Artículo :116460

    Suxin You, Zhouyun Ma, Pei Zhang, Wenwen Xu, Changsen Zhan, Nina Sang, Jiazhen Xu, Feiyun Wang, Jiange Zhang

    Resumen Resumen Esquema Esquema   
  • ·A novel combined therapeutic strategy of Nano-EN-IR@Lip mediated photothermal therapy and stem cell inhibition for gastric cancer

    Artículo :116486

    Liping Yang, Yan-e Du, Fangli Liao, Tong Huang, Yadong Liu, Junzhao Liu, Can Wang, Zhu Zhan, Yang Cao, Zhigang Wang, Weixian Chen

    Resumen Resumen Esquema Esquema   
  • ·The effects of Nardosinone on levodopa intervention in the treatment of Parkinson's disease

    Artículo :116448

    Mengmeng Liu, Jingwen Xue, Yuxin Cao, Zhuangzhuang Hao, Yuqing Wang, Jiayuan Li, Tingyue Jiang, Jinli Shi

    Resumen Resumen Esquema Esquema   
  • ·An anti-GD2 aptamer-based bifunctional spherical nucleic acid nanoplatform for synergistic therapy targeting MDM2 for retinoblastoma

    Artículo :116437

    Shijing Wang, Yan Zhao, Fei Yao, Pengxue Wei, Lan Ma, Shaochong Zhang

    Resumen Resumen Esquema Esquema   
  • ·Kefir peptides mitigate bleomycin-induced pulmonary fibrosis in mice through modulating oxidative stress, inflammation and gut microbiota

    Artículo :116431

    Ying-Wei Lan, Ying-Cheng Chen, Chih-Ching Yen, Hsiao-Ling Chen, Min-Che Tung, Hueng-Chuen Fan, Chuan-Mu Chen

    Resumen Resumen Esquema Esquema   
  • ·Empagliflozin mitigates cardiac hypertrophy through cardiac RSK/NHE-1 inhibition

    Artículo :116477

    Sha Chen, Kenneth Overberg, Zakiya Ghouse, Markus W. Hollmann, Nina C. Weber, Ruben Coronel, Coert J. Zuurbier

    Resumen Resumen Esquema Esquema   
  • ·Involvement of CB₁ and CB₂ receptors in neuroprotective effects of cannabinoids in experimental TDP-43 related frontotemporal dementia using male mice

    Artículo :116473

    Claudia Gonzalo-Consuegra, Irene Santos-García, Laura García-Toscano, Raquel Martín-Baquero, Carmen Rodríguez-Cueto, Matthias B. Wittwer, Pawel Dzygiel, Uwe Grether, Eva de Lago, Javier Fernández-Ruiz

    Resumen Resumen Esquema Esquema   
  • ·A next generation peripherally restricted Cavα2δ-1 ligand with inhibitory action on Cav2.2 channels and utility in neuropathic pain

    Artículo :116472

    Franz Kricek, Christine Ruf, Premji Meghani, Ivana A. Souza, Maria A. Gandini, Gerald W. Zamponi, George Skouteris

    Resumen Resumen Esquema Esquema  
  • ·Effects of endogenous DHA milk and exogenous DHA milk on oxidative stress and cognition in SAMP8 mice

    Artículo :116467

    Xiaodan Wang, Huiquan Zhu, Baorong Chen, Yumeng Zhang, Akke Kok, Ariette van Knegsel, Shuwen Zhang, Xiaoyang Pang, Shilong Jiang, Bas Kemp, Jing Lu, Jiaping Lv

    Resumen Resumen Esquema Esquema   
  • ·Oxymatrine alleviates high-fat diet/streptozotocin-induced non-alcoholic fatty liver disease in C57BL/6 J mice by modulating oxidative stress, inflammation and fibrosis

    Artículo :116491

    Di Lou, Qing Fang, Yinghao He, Ruyu Ma, Xinyan Wang, Hanbing Li, Minyou Qi

    Resumen Resumen Esquema Esquema  
  • ·Novel hybrid compounds of sclareol and doxorubicin as potential anticancer nanotherapy for glioblastoma

    Artículo :116496

    Ana Stepanović, Nataša Terzić Jovanović, Aleksandra Korać, Mario Zlatović, Igor Nikolić, Igor Opsenica, Milica Pešić

    Resumen Resumen Esquema Esquema   
  • ·BET inhibitor nanotherapy halts kidney damage and reduces chronic kidney disease progression after ischemia-reperfusion injury

    Artículo :116492

    Maria Laura Saiz, Laura Lozano-Chamizo, Aida Bernardo Florez, Marzia Marciello, Paula Diaz-Bulnes, Viviana Corte-Iglesias, Cristian Ruiz Bernet, Raul R. Rodrigues-Diez, Cristina Martin-Martin, Mar Rodriguez-Santamaria, Ivan Fernandez-Vega, Ramon M. Rodriguez, Carmen Diaz-Corte, Beatriz Suarez-Alvarez, Marco Filice, Carlos Lopez-Larrea

    Resumen Resumen Esquema Esquema   
  • ·Treatment with bestatin (the exogenous synthetic inhibitor of metalloproteinases) reduces the activity of metalloproteinase 2 and 12 in the spleen and lung tissues of rats in a model of lipopolysaccharide-induced sepsis

    Artículo :116480

    Barbara Nieradko-Iwanicka, Jarosław Piasecki, Andrzej Borzęcki

    Resumen Resumen Esquema Esquema  
  • ·MRGPRB2/X2 and the analogous effects of its agonist and antagonist in DSS-induced colitis in mice

    Artículo :116471

    Karthi Duraisamy, Mukesh Kumar, Abdullah Nawabjan, Emily Kwun Kwan Lo, Ming hui Lin, Benjamin Lefranc, Elsa Bonnafé, Michel Treilhou, Hani El-Nezami, Jérôme Leprince, Billy K.C. Chow

    Resumen Resumen Esquema Esquema   
  • ·Identification of ADME genes polymorphic variants linked to trastuzumab-induced cardiotoxicity in breast cancer patients: Case series of mono-institutional experience

    Artículo :116478

    Nicoletta Staropoli, Francesca Scionti, Valentina Farenza, Federica Falcone, Francesco Luciano, Maria Renne, Maria Teresa Di Martino, Domenico Ciliberto, Ludovica Tedesco, Antonella Crispino, Caterina Labanca, Maria Cucè, Stefania Esposito, Giuseppe Agapito, Mario Cannataro, Pierfrancesco Tassone, Pierosandro Tagliaferri, Mariamena Arbitrio

    Resumen Resumen Esquema Esquema  
  • ·Anti-inflammatory effect and pharmacokinetics of dehydroandrographolide, an active component of Andrographis paniculata, on Poly(I:C)-induced acute lung injury

    Artículo :116456

    Yong-Guang Liu, Shan-Shan Zhang, Su-Wei Jin, Tian-Ji Xia, Yong-Hong Liao, Rui-Le Pan, Ming-Zhu Yan, Qi Chang

    Resumen Resumen Esquema Esquema  
  • ·RETRACTED: Investigation of prunetrin induced G2/M cell cycle arrest and apoptosis via Akt/mTOR/MAPK pathways in hepatocellular carcinoma cells

    Artículo :116483

    Abuyaseer Abusaliya, Pritam Bhagwan Bhosale, Hun Hwan Kim, Min Yeong Park, Se Hyo Jeong, Sijoon Lee, Gon Sup Kim

    Resumen Resumen
  • ·Hydrogen sulfide dysfunction in metabolic syndrome-associated vascular complications involves cGMP regulation through soluble guanylyl cyclase persulfidation

    Artículo :116466

    M. Smimmo, V. Casale, G.M. Casillo, E. Mitidieri, R. d'Emmanuele di Villa Bianca, I. Bello, A. Schettino, R. Montanaro, V. Brancaleone, C. Indolfi, G. Cirino, A. Di Lorenzo, M. Bucci, E. Panza, V. Vellecco

    Resumen Resumen Esquema Esquema   
  • ·The significant improvement in ovarian PCOS syndrome using hydralazine and alendronate aromatase inhibitor FDA-approved drugs in Wistar rat models

    Artículo :116504

    Soudabeh Kavousipour, Fahimeh Koohnavard, Behzad Shahbazi, Ebrahim Eftekhar, Khadijeh Ahmadi

    Resumen Resumen Esquema Esquema  
  • ·Direct exposure to CpG and specific antigens mitigate airway allergy through modulating dendritic cell properties

    Artículo :116510

    Aizhi Zhang, Lihua Mo, Xiaoxue Chen, Ping Tang, Yu Liu, Wenkai Zhang, Cheng Zhang, Cailing Wang, Huanping Zhang, Pingchang Yang

    Resumen Resumen Esquema Esquema   
  • ·TMF inhibits extracellular matrix degradation by regulating the C/EBPβ/ADAMTS5 signaling pathway in osteoarthritis

    Artículo :116501

    Zeyu Wang, Weimei Shi, Longhuo Wu, Yaosheng Xiao, Miaofei Wang, Sainan Zhang, Zhixi Chen, Guoqiang Yin, Xunlu Xie, Shengrong Bi, Shiwei Liu, Weihao Kong, Jianguo Zhou

    Resumen Resumen Esquema Esquema  
  • ·Lactoferrin as a therapeutic agent for attenuating hepatic stellate cell activation in thioacetamide-induced liver fibrosis

    Artículo :116490

    Tzu-Yu Pu, Kai-Cheng Chuang, Min-Che Tung, Chih-Ching Yen, Yu-Hsuan Chen, Abdulkadir Cidem, Chu-Hsun Ko, Wei Chen, Chuan-Mu Chen

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  • ·Construction of aptamer-siRNA chimera and glutamine modified carboxymethyl-β-cyclodextrin nanoparticles for the combination therapy against lung squamous cell carcinoma

    Artículo :116506

    Yanfei Hao, Jintao Yang, Dongxu Liu, Hong Zhang, Tongwen Ou, Li Xiao, Wen Chen

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  • ·Predicting potential therapeutic targets and small molecule drugs for early-stage lung adenocarcinoma

    Artículo :116528

    Yongxin Yu, Lingchen Li, Bangyu Luo, Diangang Chen, Chenrui Yin, Chunli Jian, Qiai You, Jianmin Wang, Ling Fang, Dingqin Cai, Jianguo Sun

    Resumen Resumen Esquema Esquema   
  • ·Chrysin inhibits ferroptosis of cerebral ischemia/reperfusion injury via regulating HIF-1α/CP loop

    Artículo :116500

    Jinfeng Shang, Jiakang Jiao, Jingyi Wang, Mingxue Yan, Qiannan Li, Lizha Shabuerjiang, Guijinfeng Huang, Qi Song, Yinlian Wen, Xiaolu Zhang, Kai Wu, Yiran Cui, Xin Liu

    Resumen Resumen Esquema Esquema   
  • ·Synergistic targeting of TrxR1 and ATM/AKT pathway in human colon cancer cells

    Artículo :116507

    Xin Shen, Yiqun Xia, Hui Lu, Peisen Zheng, Junqi Wang, Yinghua Chen, Chenxin Xu, Chenyu Qiu, Yafei Zhang, Zhongxiang Xiao, Peng Zou, Ri Cui, Daoyong Ni

    Resumen Resumen Esquema Esquema   
  • ·The isoproterenol-induced myocardial fibrosis: A biochemical and histological investigation

    Artículo :116534

    Lorenzo Flori, Giulia Lazzarini, Jacopo Spezzini, Andrea Pirone, Vincenzo Calderone, Lara Testai, Vincenzo Miragliotta

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  • ·DMC-siERCC2 hybrid nanoparticle enhances TRAIL sensitivity by inducing cell cycle arrest for glioblastoma treatment

    Artículo :116470

    Meihui Song, Tengfei Wang, Tao Liu, Ting Lei, Xu Teng, Qian Peng, Qihui Zhu, Feng Chen, Guifang Zhao, Kaishu Li, Ling Qi

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  • ·Enhancing the therapeutic potential of isoliensinine for hypertension through PEG-PLGA nanoparticle delivery: A comprehensive in vivo and in vitro study

    Artículo :116541

    Mengying Yao, Ming Wu, Meng Yuan, Meizhu Wu, Aling Shen, Youqin Chen, Dawei Lian, Xiaolong Liu, Jun Peng

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  • ·Pilose antler extract promotes hair growth in androgenic alopecia mice by promoting the initial anagen phase

    Artículo :116503

    Menghua Liu, Gaiying He, Fenglong Wang, Yanan Sun, Shuhua Ma, Yu Hao, Yi Wang

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  • ·Inhibition of calcium-sensing receptor by its antagonist promotes gastrointestinal motility in a Parkinson’s disease mouse model

    Artículo :116518

    Yu-Hang Li, Zhong-Xin Jiang, Qian Xu, Ting-Ting Jin, Jin-Fang Huang, Xiao Luan, Chong Li, Xin-Yi Chen, Ka-Hing Wong, Xiao-Li Dong, Xiang-Rong Sun

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  • ·Multitarget action of Benzothiazole-piperazine small hybrid molecule against Alzheimer's disease: In silico, In vitro, and In vivo investigation

    Artículo :116484

    Chandra Bhushan Mishra, Shruti Shalini, Siddharth Gusain, Pawan Kumar, Shikha Kumari, Yong-Sung Choi, Jyoti Kumari, Bala Krishna Moku, Anita Kumari Yadav, Amresh Prakash, Raok Jeon, Manisha Tiwari

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  • ·Protective effect of esculentoside A against myocardial infarction via targeting C-X-C motif chemokine receptor 2

    Artículo :116529

    Meng Gao, Qing Cai, Yehua Bian, Zhuoya Wang, Lina Xu, Jinyong Peng

    Resumen Resumen Esquema Esquema   
  • ·Host-microbiota interactions in collagen-induced arthritis rats treated with human umbilical cord mesenchymal stem cell exosome and ginsenoside Rh2

    Artículo :116515

    Zhongsheng Zhou, Yang Li, Shuhui Wu, Te Liu, Jinlan Jiang

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  • ·Curcumin prevents high glucose-induced stimulatory effects of renal cell secretome on fibroblast activation via mitigating intracellular free radicals and TGF-β secretion

    Artículo :116536

    Chadanat Noonin, Visith Thongboonkerd

    Resumen Resumen Esquema Esquema  
  • ·Free fatty acid receptor 4 (FFA4) activation attenuates obese asthma by suppressing adiposity and resolving metaflammation

    Artículo :116509

    So-Eun Son, Jung-Min Koh, Dong-Soon Im

    Resumen Resumen Esquema Esquema  
  • ·Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: Analysis of a database of 432 patients developed by literature review and machine learning support

    Artículo :116530

    Marta Moreno-Torres, Ernesto López-Pascual, Anna Rapisarda, Guillermo Quintás, Annika Drees, Inger-Lise Steffensen, Thomas Luechtefeld, Eva Serrano-Candelas, Marina Garcia de Lomana, Domenico Gadaleta, Hubert Dirven, Mathieu Vinken, Ramiro Jover

    Resumen Resumen Esquema Esquema   
  • ·Epigallocatechin-3-gallate confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis, apoptosis, and autophagy via modulation of 14–3-3η

    Artículo :116542

    Tie Hu, Fa-Jia Hu, Huang Huang, Ze-Yu Zhang, Ya-Mei Qiao, Wen-Xiong Huang, Yi-Cheng Wang, Xin-Yi Tang, Song-Qing Lai

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  • ·Targeting liver and adipose tissue in obese mice: Effects of a N-acylethanolamine mixture on insulin resistance and adipocyte reprogramming

    Artículo :116531

    S. Melini, A. Lama, F. Comella, N. Opallo, F. Del Piano, C. Annunziata, M.P. Mollica, M.C. Ferrante, C. Pirozzi, G. Mattace Raso, R. Meli

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  • ·Industrial-produced lemon nanovesicles ameliorate experimental colitis-associated damages in rats via the activation of anti-inflammatory and antioxidant responses and microbiota modification

    Artículo :116514

    Vincenza Tinnirello, Maria Grazia Zizzo, Alice Conigliaro, Mariangela Tabone, Nima Rabienezhad Ganji, Adele Cicio, Carlo Bressa, Mar Larrosa, Francesca Rappa, Giuseppe Vergilio, Roberta Gasparro, Alessia Gallo, Rosa Maria Serio, Riccardo Alessandro, Stefania Raimondo

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  • ·Mitigation of inflammatory bowel disease-related osteoporosis by oxyberberine: Insights into the RANKL/NF-κB signaling pathway

    Artículo :116523

    Tingting Chen, Gaoxiang Ai, Guihong Liang, Lingfeng Zeng, Di Zhao, Jun Liu, Yaoxing Dou

    Resumen Resumen Esquema Esquema   
  • ·Antinociceptive effect of LMH-2, a new sigma-1 receptor antagonist analog of haloperidol, on the neuropathic pain of diabetic mice

    Artículo :116524

    Rosa Ventura-Martínez, Guadalupe Esther Ángeles-López, Diana González-Ugalde, Tania Domínguez-Páez, Gabriel Navarrete-Vázquez, Ruth Jaimez, Myrna Déciga-Campos

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  • ·Equisetum arvense standardized dried extract hinders age-related osteosarcopenia

    Artículo :116517

    Laura Salvadori, Martina Paiella, Beatrice Castiglioni, Maria Laura Belladonna, Tommaso Manenti, Catia Ercolani, Luca Cornioli, Nausicaa Clemente, Andrea Scircoli, Roccaldo Sardella, Leonardo Tensi, Andrea Astolfi, Maria Letizia Barreca, Sara Chiappalupi, Giulia Gentili, Michela Bosetti, Guglielmo Sorci, Nicoletta Filigheddu, Francesca Riuzzi

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  • ·Memantine suppresses the excitotoxicity but fails to rescue the ataxic phenotype in SCA1 model mice

    Artículo :116526

    Olga S. Belozor, Alex Vasilev, Alexandra G. Mileiko, Lyudmila D. Mosina, Ilya G. Mikhailov, Darius A. Ox, Elizaveta B. Boitsova, Andrey N. Shuvaev, Anja G. Teschemacher, Sergey Kasparov, Anton N. Shuvaev

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  • ·Biomedicine and pharmacotherapeutic effectiveness of combinatorial atorvastatin and quercetin on diabetic nephropathy: An in vitro study

    Artículo :116533

    Haleema Shahin DH, Rokeya Sultana, Ashwini Prabhu, Pavan S.R, Sourav Mohanto, Vetriselvan Subramaniyan

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  • ·Proposal for considerations during human iPSC-derived cardiac organoid generation for cardiotoxicity drug testing

    Artículo :116511

    Sang Woo Lee, MyeongJin Song, Dong-Hun Woo, Gi Seok Jeong

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  • ·Canagliflozin inhibits PASMCs proliferation via regulating SGLT1/AMPK signaling and attenuates artery remodeling in MCT-induced pulmonary arterial hypertension

    Artículo :116505

    Xiaojun Chen, Xing Yu, Guili Lian, Huibin Tang, Yan Yan, Gufeng Gao, Bangbang Huang, Li Luo, Liangdi Xie

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  • ·A novel HDAC8 inhibitor H7E exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress

    Artículo :116538

    Liang-Huan Wu, Yu-Wen Cheng, Fan-Li Lin, Kai-Cheng Hsu, Mong-Heng Wang, Jing-Lun Yen, Tsung-Jen Wang, Tony Eight Lin, Yi-Chien Liu, Wei-Jan Huang, George Hsiao

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  • ·RNA expression changes driven by altered epigenetics status related to NASH etiology

    Artículo :116508

    Daniel Castellano-Castillo, Bruno Ramos-Molina, María Dolores Frutos, Isabel Arranz-Salas, Armando Reyes-Engel, María Isabel Queipo-Ortuño, Fernando Cardona

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  • ·Targeted delivery of NO donor and ROS scavenger for synergistic treatment of rheumatoid arthritis

    Artículo :116540

    Rongrong Luo, Jingjing Su, Wenying Zhang, Wenguang Huang, Qianqian Zhou, Pengchao Sun, Yongxing Zhao

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  • ·A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients

    Artículo :116537

    Sara Rossi, Vanessa Tatangelo, Maria Dichiara, Stefania Butini, Sandra Gemma, Simone Brogi, Silvia Pasquini, Martina Cappello, Fabrizio Vincenzi, Katia Varani, Ludovica Lopresti, Margherita Malchiodi, Chiara Carrara, Alessandro Gozzetti, Monica Bocchia, Giuseppe Marotta, Laura Patrussi, Gabriele Carullo, Cosima T. Baldari, Giuseppe Campiani

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  • ·Therapeutic potential of LINS01 histamine H₃ receptor antagonists as antineoplastic agents for triple negative breast cancer

    Artículo :116527

    Ignacio A. Ospital, Mónica A. Táquez Delgado, Melisa B. Nicoud, Michelle F. Corrêa, Gustavo A. Borges Fernandes, Isabela W. Andrade, Paolo Lauretta, Rocío Martínez Vivot, María Betina Comba, María Marta Zanardi, Daniela Speisky, Juan L. Uriburu, João P.S. Fernandes, Vanina A. Medina

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  • ·Hepatoprotective and cardioprotective effects of empagliflozin in spontaneously hypertensive rats fed a high-fat diet

    Artículo :116520

    Silvie Hojná, Hana Malínská, Martina Hüttl, Zdeňka Vaňourková, Irena Marková, Denisa Miklánková, Jaroslav Hrdlička, František Papoušek, Jan Neckář, Petr Kujal, Michal Behuliak, Hana Rauchová, Michaela Kadlecová, David Sedmera, Kristýna Neffeová, Eva Zábrodská, Veronika Olejníčková, Josef Zicha, Ivana Vaněčková

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  • ·Sacubitril/Valsartan inhibits M1 type macrophages polarization in acute myocarditis by targeting C-type natriuretic peptide

    Artículo :116535

    Changhu Liu, Qi Long, Han Yang, Hongmin Yang, Yaohan Tang, Bingjun Liu, Zihua Zhou, Jing Yuan

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  • ·Halimane Derivatives from Plectranthus ornatus Codd. as Novel Anti-cancer Agents

    Artículo :116516

    Gabrielle Bangay, Florencia Z. Brauning, Tomasz Kowalczyk, Anna Merecz-Sadowska, Ewelina Synowiec, Tomasz Śliwiński, Nuno Candeias, Monica S. Estevão, Carlos A.M. Afonso, Vânia André, Przemysław Sitarek, Patrícia Rijo

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  • ·Myricanol improves metabolic profiles in dexamethasone induced lipid and protein metabolism disorders in mice

    Artículo :116557

    Tiandan Li, Xiaochao Hu, Lingyang Fan, Yong Yang, Kai He

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  • ·Mastoparan M promotes functional recovery in stroke mice by activating autophagy and inhibiting ferroptosis

    Artículo :116560

    Qian Wang, Chaojie Liu, Mingran Chen, Jie Zhao, Dexiao Wang, Pengfei Gao, Chenggui Zhang, Hairong Zhao

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  • ·Characterization of the structure, anti-inflammatory activity and molecular docking of a neutral polysaccharide separated from American ginseng berries

    Artículo :116521

    Qixiang Feng, Huijiao Yan, Yu Feng, Li Cui, Hidayat Hussain, Jeong Hill Park, Sung Won Kwon, Lei Xie, Yan Zhao, Zhihao Zhang, Jinfan Li, Daijie Wang

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  • ·The impact of daily supplementation with rhamnogalacturonan-I on the gut microbiota in healthy adults: A randomized controlled trial

    Artículo :116561

    Ching Jian, Nikolaj Sorensen, René Lutter, Ruud Albers, Willem de Vos, Anne Salonen, Annick Mercenier

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  • ·Total ginsenosides decrease Aβ production through activating PPARγ

    Artículo :116577

    Shan He, Junhe Shi, Lina Ma, Hui Pei, Ping Zhang, Dazhuo Shi, Hao Li

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  • ·Trimethylamine-N-oxide aggravated the sympathetic excitation in D-galactose induced aging rats by down-regulating P2Y12 receptor in microglia

    Artículo :116549

    Ping Wang, Yuan Mi, Hao Yu, Xu Teng, Sheng Jin, Lin Xiao, Hongmei Xue, Danyang Tian, Qi Guo, Yuming Wu

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  • ·Phosphorylation-dependent allosteric regulation of Cx43 gap junction inhibitor potency

    Artículo :116550

    Rokas Mickus, Vytautas Raškevičius, Ieva Sarapinienė, Valeryia Mikalayeva, Rytis Prekeris, Vytenis Arvydas Skeberdis

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  • ·Safflower polysaccharide ameliorates acute ulcerative colitis by regulating STAT3/NF-κB signaling pathways and repairing intestinal barrier function

    Artículo :116553

    Man Qi, Shenghui Chu, Wenxuan Wang, Xianglei Fu, Chao Jiang, Liang Zhang, MD Hasan Ali, Yating Lu, Mengwei Jia, Dilraba Ubul, Hui Tang, Jian Li, Min Liu

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  • ·Intestinal inflammation marker calprotectin regulates epithelial intestinal zinc metabolism and proliferation in mouse jejunal organoids

    Artículo :116555

    R. González, D. Ceacero-Heras, M. Tena-Garitaonaindia, A. Álvarez-Mercado, R. Gámez-Belmonte, W.J. Chazin, F. Sánchez de Medina, O. Martínez-Augustin

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  • ·Establishment of a model of LPS-induced inflammatory injury in human aortic endothelial cells

    Artículo :116576

    Yan Zhang, Yudi Feng, Suoni Zhou, Shuochen Gao, Bo Xiong, Xueyan Gao, Yi Song, Lin Liu, Chengzeng Wang, Ying Yang

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  • ·S1PR3 agonism and S1P lyase inhibition rescue mice in the severe state of experimental sepsis

    Artículo :116575

    Anke C. Ziegler, Raphael S. Haider, Carsten Hoffmann, Markus H. Gräler

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  • ·NGF increases Connexin-43 expression and function in pulmonary arterial smooth muscle cells to induce pulmonary artery hyperreactivity

    Artículo :116552

    Guillaume Cardouat, Matthieu Douard, Clément Bouchet, Lukas Roubenne, Zuzana Kmecová, Pauline Esteves, Fabien Brette, Christophe Guignabert, Ly Tu, Marilyne Campagnac, Paul Robillard, Florence Coste, Frédéric Delcambre, Matthieu Thumerel, Hugues Begueret, Arnaud Maurac, Yaniss Belaroussi, Jan Klimas, Thomas Ducret, Jean-François Quignard, Pierre Vacher, Isabelle Baudrimont, Roger Marthan, Patrick Berger, Christelle Guibert, Véronique Freund-Michel

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  • ·Vitamin B₆ alleviates chronic sleep deprivation-induced hippocampal ferroptosis through CBS/GSH/GPX4 pathway

    Artículo :116547

    Man Yuan, Feng Wang, Tieqiang Sun, Xiangyu Bian, Yuxian Zhang, Changjiang Guo, Lixia Yu, Zhanxin Yao

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  • ·Effect of adalimumab as an anti-inflammatory agent on gene expression of retinal pigment epithelial cells

    Artículo :116568

    M. Hossein Nowroozzadeh, Mojtaba Yousefi, Mostafa Abuali, Fatemeh Sanie-Jahromi

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  • ·Chinese medicinal formula Fu Xin decoction against chronic heart failure by inhibiting the NLRP3/caspase-1/GSDMD pyroptotic pathway

    Artículo :116548

    Lei Zhang, Yan Li, Cun-dong Fan, Yong-Hao Jiang, Li-song Sheng, Xu-yu Song, Yu-xing Lin, Yi-Tao Xue, Rong Sun

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  • ·Co-administration of “L-Lysine, Vitamin C, and Zinc” increased the antioxidant activity, decreased insulin resistance, and improved lipid profile in streptozotocin-induced diabetic rats

    Artículo :116525

    Mostafa Yousefian, Saeid Abedimanesh, Amirhossein Yadegar, Manouchehr Nakhjavani, S. Zahra Bathaie

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  • ·In vivo effects of a selected thiourea derivative 1-(2-chlorobenzoyl)-3-(2,3-dichlorophenyl) against nociception, inflammation and gastric ulcerogenicity: Biochemical, histopathological and in silico approaches

    Artículo :116544

    Gowhar Ali, Farrah Deeba, Umer Rashid, Aman Ullah, Hammad Ullah, Inayat Ali Khan, Syed Ishtiaq Khan, Amin Badshah, Muhammad Arif Khan, Muhammad Ayaz, Maria Daglia

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  • ·Indirubin-3′-monoxime exhibits potent antiviral and anti-inflammatory effects against human adenoviruses in vitro and in vivo

    Artículo :116558

    Junyu Wang, Chaojie Yang, Zhixin Liang, Junping Sun, Mingyue Zhang, Shaofu Qiu, Xinying Du, Xi He, Xiaoying Pang, Xidong Ma, Mei Xie, Xinjie Han, Ru Fan, Enlu Zhou, Hairong Yu, Danyang She, Hongbin Song, Jianxin Wang

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  • ·Toxic side-effects of diaspirin cross-linked human hemoglobin are attenuated by the apohemoglobin-haptoglobin complex

    Artículo :116569

    Carlos J. Munoz, Daniela Lucas, Jacinda Martinez, Mia Ricario, Quintin T. O'Boyle, Ivan S. Pires, Andre F. Palmer, Pedro Cabrales

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  • ·Characterization of a novel T cell-engaging bispecific antibody for elimination of L1CAM-positive tumors

    Artículo :116565

    Yuan Yuan, Junyan Li, Jie Chen, Lei Han, Lei Wang, Yali Yue, Junjun Liu, Baohong Zhang, Yunsheng Yuan, Mingyuan Wu, Yanlin Bian, Yueqing Xie, Jianwei Zhu

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  • ·Resolvin D2 prevents vascular remodeling, hypercontractility and endothelial dysfunction in obese hypertensive mice through modulation of vascular and proinflammatory factors

    Artículo :116564

    Raquel Rodrigues-Diez, Constanza Ballesteros-Martinez, Rosa María Moreno-Carriles, Francisco Nistal, Lucía S. Díaz del Campo, Victoria Cachofeiro, Jesmond Dalli, Ana B. García-Redondo, Juan M. Redondo, Mercedes Salaices, Ana M. Briones

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  • ·The use of a selective, nontoxic dual-acting peptide for breast cancer patients with brain metastasis

    Artículo :116573

    Marco Cavaco, Clara Pérez-Peinado, Javier Valle, Ruben D.M. Silva, Lurdes Gano, João D.G. Correia, David Andreu, Miguel A.R.B. Castanho, Vera Neves

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  • ·The effect of calpain inhibitor-I on copper oxide nanoparticle-induced damage and cerebral ischemia-reperfusion in a rat model

    Artículo :116539

    Hadi Karimkhani, Paria Shojaolsadati, Türkan Yiğitbaşı, Bircan Kolbası, Neslin Emekli

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  • ·Xanthohumol, a prenylated chalcone, regulates lipid metabolism by modulating the LXRα/RXR-ANGPTL3-LPL axis in hepatic cell lines and high-fat diet-fed zebrafish models

    Artículo :116598

    Wan-Yun Gao, Pei-Yi Chen, Hao-Jen Hsu, Je-Wen Liou, Chia-Ling Wu, Ming-Jiuan Wu, Jui-Hung Yen

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  • ·Activation of the IL-6/STAT3 pathway contributes to the pathogenesis of membranous nephropathy and is a target for Mahuang Fuzi and Shenzhuo Decoction (MFSD) to repair podocyte damage

    Artículo :116583

    Qihan Zhao, Haoran Dai, Hanxue Jiang, Naiqian Zhang, Fanyu Hou, Yang Zheng, Yu Gao, Wenbin Liu, Zhendong Feng, Yuehong Hu, Xinyue Tang, Hongliang Rui, Baoli Liu

    Resumen Resumen Esquema Esquema   
  • ·Novel small molecule DMAMCL induces differentiation in rhabdomyosarcoma by downregulating of DLL1

    Artículo :116562

    Qi Li, Yexi Chen, Yang Chen, Zhongyan Hua, Baocheng Gong, Zhihui Liu, Carol J. Thiele, Zhijie Li

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  • ·Curcumin regulates pulmonary extracellular matrix remodeling and mitochondrial function to attenuate pulmonary fibrosis by regulating the miR-29a-3p/DNMT3A axis

    Artículo :116572

    Meng-Hsuan Cheng, Hsuan-Fu Kuo, Chia-Yuan Chang, Jui-Chi Chang, I.-Fan Liu, Chong-Chao Hsieh, Chih-Hsin Hsu, Chia-Yang Li, Shu-Chi Wang, Yung-Hsiang Chen, Chuang-Rung Chang, Tsung-Ying Lee, Yu-Ru Liu, Chi-Yuan Huang, Szu-Hui Wu, Wei-Lun Liu, Po-Len Liu

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  • ·Cytotoxicity, anti-inflammatory effect, and acute oral toxicity of a novel Attalea phalerata kernel oil-loaded nanocapsules

    Artículo :116308

    Bianca Rodrigues Acácio, Ariadna Lafourcade Prada, Serafim Florentino Neto, Giovana Bicudo Gomes, Renata Trentin Perdomo, Carlos Eduardo Domingues Nazario, Eduardo Sobieski Neto, Marco António Utrera Martines, Danielle Ayr Tavares de Almeida, Arquimedes Gasparotto Junior, Jesus Rafael Rodriguez Amado

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  • ·Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin’s neuroprotective action against diabetes-induced cognitive impairment

    Artículo :116579

    Yanfang Zheng, Chenxiang Wang, Wenjing Liu, Jiaying Chen, Yibin Sun, Dennis Chang, Huan Wang, Wen Xu, Jin-Jian Lu, Xian Zhou, Mingqing Huang

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  • ·Hydrangea serrata extract attenuates PM-exacerbated airway inflammation in the CARAS model by modulating the IL-33/ST2/NF-κB signaling pathway

    Artículo :116596

    Juan Jin, Thi Van Nguyen, Yuna Jiang, Zhen Nan Yu, Chang Ho Song, So-Young Lee, Hee Soon Shin, Ok Hee Chai

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  • ·Tectorigenin protects against cardiac fibrosis in diabetic mice heart via activating the adiponectin receptor 1-mediated AMPK pathway

    Artículo :116589

    Yu-Lan Ma, Man Xu, Xian-Feng Cen, Hong-Liang Qiu, Ying-Ying Guo, Qi-Zhu Tang

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  • ·Interaction of selected alkoxy naringenin oximes with model and bacterial membranes

    Artículo :116581

    Olga Wesołowska, Anna Duda-Madej, Maria Błaszczyk, Kamila Środa-Pomianek, Joanna Kozłowska, Mirosław Anioł

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  • ·Physical training mitigates alveolar bone and blood enzymatic antioxidants defense impairment induced by binge ethanol consumption in rats

    Artículo :116554

    Beatriz Rodrigues Risuenho Peinado, Deborah Ribeiro Frazão, Victória Santos Chemelo, José Mario Matos-Souza, Railson de Oliveira Ferreira, Leonardo Oliveira Bittencourt, Gabriela de Souza Balbinot, Fabrício Mezzomo Collares, Luanna Melo Pereira Fernandes, Cristiane Socorro Ferraz Maia, Rafael Rodrigues Lima

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  • ·Identification of Riluzole derivatives as novel calmodulin inhibitors with neuroprotective activity by a joint synthesis, biosensor, and computational guided strategy

    Artículo :116602

    Maider Baltasar-Marchueta, Leire Llona, Sara M-Alicante, Iratxe Barbolla, Markel Garcia Ibarluzea, Rafael Ramis, Ane Miren Salomon, Brenda Fundora, Ariane Araujo, Arantza Muguruza-Montero, Eider Nuñez, Scarlett Pérez-Olea, Christian Villanueva, Aritz Leonardo, Sonia Arrasate, Nuria Sotomayor, Alvaro Villarroel, Aitor Bergara, Esther Lete, Humberto González-Díaz

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  • ·Caffeic acid alleviates skeletal muscle atrophy in 5/6 nephrectomy rats through the TLR4/MYD88/NF-kB pathway

    Artículo :116556

    Jinyue He, Zhuoen He, Hao Wang, Chi Zhang, Tingting Pei, Shihua Yan, Yangtian Yan, Fujing Wang, Yuchi Chen, Ningning Yuan, Mingqing Wang, Wei Xiao

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  • ·Intratumoural delivery of TRAIL mRNA induces colon cancer cell apoptosis

    Artículo :116603

    Tingxuan Gu, Mengqiao Wang, Xiaorong Fu, Xueli Tian, Juanjuan Bi, Ning Lu, Chen Chen, Shijia Yan, Ang Li, Luyun Wang, Xiang Li, Kangdong Liu, Zigang Dong

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  • ·Iguratimod inhibits protein citrullination and inflammation by downregulating NBCe2 in patients with rheumatoid arthritis

    Artículo :116551

    Tiane Peng, Bingtong Li, Liqi Bi, Fangze Zhang

    Resumen Resumen Esquema Esquema   
  • ·Improving the mechanical and biological functions of cell sheet constructs: The interplay of human-derived periodontal ligament stem cells, endothelial cells and plasma rich in growth factors

    Artículo :116599

    Eduardo Anitua, María Troya, Mar Zalduendo, Roberto Tierno, Mohammad H. Alkhraisat, Nerea Osinalde, Asier Fullaondo, Ana M. Zubiaga

    Resumen Resumen Esquema Esquema   
  • ·Hydrogels containing KYNA promote angiogenesis and inhibit inflammation to improve the survival rate of multi-territory perforator flaps

    Artículo :116454

    Ya-wei Zhang, Xiaoyang Pang, Yan Yang

    Resumen Resumen Esquema Esquema  
  • ·Role of ghrelin hormone in the development of alcohol-associated liver disease

    Artículo :116595

    Sundararajan Mahalingam, Ramesh Bellamkonda, Kusum K. Kharbanda, Madan Kumar Arumugam, Vikas Kumar, Carol A. Casey, Lorenzo Leggio, Karuna Rasineni

    Resumen Resumen Esquema Esquema   
  • ·Conjugation of sulpiride with a cell penetrating peptide to augment the antidepressant efficacy and reduce serum prolactin levels

    Artículo :116610

    Yuan Liang, Yu Yang, Ruiyan Huang, Jiangyue Ning, Xingyan Bao, Zelong Yan, Haotian Chen, Li Ding, Chang Shu

    Resumen Resumen Esquema Esquema   
  • ·Theabrownin from Qingzhuan tea prevents high-fat diet-induced MASLD via regulating intestinal microbiota

    Artículo :116582

    Yong Chen, Chen Xie, Yining Lei, Dan Ye, Le Wang, Fang Xiong, Hui Wu, Qiang He, Hongfu Zhou, Ling Li, Jun Xing, Cai Wang, Min Zheng

    Resumen Resumen Esquema Esquema  
  • ·Salidroside promotes angiogenesis after cerebral ischemia in mice through Shh signaling pathway

    Artículo :116625

    Ying Li, Weihong Xue, Songyi Li, Lili Cui, Yuxiao Gao, Linlin Li, Rong Chen, Xiao Zhang, Renhao Xu, Wei Jiang, Xiangjian Zhang, Lina Wang

    Resumen Resumen Esquema Esquema  
  • ·Zhen-Wu-Tang ameliorates lupus nephritis by diminishing renal tissue-resident memory CD8⁺ T cells via suppressing IL-15/STAT3 pathway

    Artículo :116597

    Chun-Ling Liang, Yu-Yan Wei, Yi Chen, Yini Luo, Fenglian Qin, Yuchao Chen, Huazhen Liu, Feifei Qiu, Junbiao Wu, Bin Yang, Yuntao Liu, Zhenhua Dai

    Resumen Resumen Esquema Esquema  
  • ·A high-dose of ursodeoxycholic acid treatment alleviates liver inflammation by remodeling gut microbiota and bile acid profile in a mouse model of non-alcoholic steatohepatitis

    Artículo :116617

    Hu Li, Mingjie Wang, Peizhan Chen, Mingyu Zhu, Li Chen

    Resumen Resumen Esquema Esquema   
  • ·919 granules improve postpartum depression through the regulation of abnormal peripheral blood IL-1β

    Artículo :116623

    Shusheng Wang, Yan Zhao, Zhicheng Yang, Yujun Liu, Ru Xu, Ruoxin Tu, Songping Liu, Xin Zou, Lan Zhang, Jie Hao, Pengfei Gao

    Resumen Resumen Esquema Esquema   
  • ·A rational designed multi-epitope vaccine elicited robust protective efficacy against Klebsiella pneumoniae lung infection

    Artículo :116611

    Jingwen Liao, Xiaoli Zhang, Xi Zeng, Zhuo Zhao, Tianjun Sun, Zhenping Xia, Haiming Jing, Yue Yuan, Zhifu Chen, Qiang Gou, Liqun Zhao, Weijun Zhang, Quanming Zou, Jinyong Zhang

    Resumen Resumen Esquema Esquema   

• Letters to the Editor

  • ·Response to antifibrotic therapy and decrease of circulating BAG3 protein levels in systemic sclerosis patients with reduced forced vital capacity

    Artículo :116578

    Margot De Marco, Anna Basile, Anna Lisa Cammarota, Claudia Iannone, Antonia Falco, Liberato Marzullo, Alessandra Rosati, Roberto Caporali, Maria Caterina Turco, Nicoletta Del Papa

    Esquema Esquema  

• Corrigendum

  • ·Corrigendum to “5-Bromo-3,4-dihydroxybenzaldehyde attenuates endothelial cells injury from high glucose-induced damage” [Biomed. Pharmacother. 155 (2022) 113793]

    Artículo :116498

    Qionghua Wang, Kepeng Ou, Chunqin Zeng, Yanhong Fang

     
  • ·Corrigendum to “β-Asarone suppresses Wnt/β-catenin signaling to reduce viability, inhibit migration/invasion/adhesion and induce mitochondria-related apoptosis in lung cancer cells” [Biomed. Pharmacother. 106 (2018) 821–830]

    Artículo :116499

    Tao-Li Wang, Chen-Sheng Ouyang, Li-Zhu Lin