Candida bloodstream infection in patients with systemic autoimmune diseases - 13/05/20
Candidémie chez les patients atteints de maladies auto-immunes systémiques
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Highlights |
• | Candida albicans is the most frequent etiology of candidemia in patients with systemic autoimmune diseases. |
• | Mortality rates among patients with systemic autoimmune diseases do not differ from those found in the general population. |
Abstract |
Objectives |
To describe the epidemiological, clinical and microbiological characteristics and mortality of patients with Candida bloodstream infection and systemic autoimmune diseases.
Methods |
We performed a retrospective multicenter study of candidemia in adults with systemic autoimmune diseases between 2010 and 2016.
Results |
Among 1040 patients with candidemia, 36 (3.5%) had a systemic autoimmune disease. The most common systemic autoimmune disease was rheumatoid arthritis (27.8%). The most common species was Candida albicans (66.7%). Twenty-two (61.1%) patients received a corticosteroid therapy and nine (25%) received an immunosuppressive therapy at the time of candidemia. The mortality rate was 27.8%.
Conclusions |
Systemic autoimmune diseases are not common in patients with candidemia. The unadjusted mortality rate was comparable to other candidemia studies in the general population.
Il testo completo di questo articolo è disponibile in PDF.Keywords : Candidemia, Corticosteroid therapy, Immunosuppressive therapy, Systemic autoimmune disease
Mappa
Vol 50 - N° 4
P. 372-376 - Giugno 2020 Ritorno al numeroBenvenuto su EM|consulte, il riferimento dei professionisti della salute.
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