Heterogeneous response to spesolimab in pyoderma gangrenosum depends on underlying myeloid disorders - 18/12/25
Doi : 10.1016/j.jaad.2025.08.084
Youcong Wang, MD, Yeping Ruan, MD, Mengya Chen, MD, Xiaoqing Zhao, MD, Xia Li, MD, Meng Pan, MD, PhD, Jie Zheng, MD, PhD ⁎ 
, Lihong Chen, MD ⁎
, Lihong Chen, MD ⁎ Department of Dermatology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
∗Correspondence to: Lihong Chen, MD, and Jie Zheng, MD, PhD, Department of Dermatology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, No. 197, Rui Jin Er Rd, Huangpu District, Shanghai 200025, P.R. ChinaDepartment of DermatologyRui Jin HospitalShanghai Jiao Tong University School of MedicineNo. 197, Rui Jin Er RdHuangpu DistrictShanghai200025P.R. China
Key words : myeloid disorders, pyoderma gangrenosum, spesolimab
| Drs Wang, Ruan, and Chen are co-first authors with equal contributions. Drs Zheng and Chen are co-corresponding author. |
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| Funding sources: This study was funded by the National Natural Science Foundation of China (Key Program, 81830095 ), Shanghai Municipal Education Commission – Gaofeng Clinical Medicine Grant Support ( 20172009 ), and Innovative research team of high-level local universities in Shanghai ( SHSMU-ZDCX20211002 ). |
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| Patient consent: The authors attest to obtaining written patient consent for the publication of recognizable patient photographs or other identifiable material, with the understanding that this information may be publicly available. |
|
| IRB approval status: Not applicable. |
© 2025
American Academy of Dermatology, Inc.. Pubblicato da Elsevier Masson SAS. Tutti i diritti riservati.
Vol 94 - N° 1
P. 229-231 - gennaio 2026 Ritorno al numero
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