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Factors Affecting Volume Load Management in Patients With Heart Failure: A Path Analysis Using a Multimediation Model - 02/04/26

Doi : 10.1016/j.hlc.2025.09.016 
Qiuping Wu, MN a, 1, Haoyu Pei, BN b, 1, Limin Zhang, BN a, Yulu Chen, MN c, Lei Wang, MN d, Jing He, MN e, , Caiping Song, MN f,
a Department of Cardiology, Xinqiao Hospital and The Second Affiliated Hospital of Army Medical University, Chongqing, China 
b Department of Anesthesiology, Army Medical Center of PLA, Chongqing, China 
c Department of Otolaryngology, Xinqiao Hospital and The Second Affiliated Hospital of Army Medical University, Chongqing, China 
d Department of Orthopedics, Xinqiao Hospital and The Second Affiliated Hospital of Army Medical University, Chongqing, China 
e Department of Hospital Infection Control, Xinqiao Hospital and The Second Affiliated Hospital of Army Medical University, Chongqing, China 
f President Office, Xinqiao Hospital and The Second Affiliated Hospital of Army Medical University, Chongqing, China 

Corresponding author at: Department of Hospital Infection Control, Xinqiao Hospital and The Second Affiliated Hospital of Army Medical University, Chongqing 400037, China Department of Hospital Infection Control Xinqiao Hospital and The Second Affiliated Hospital of Army Medical University Chongqing 400037 China ∗∗ Corresponding author at: President Office, Xinqiao Hospital and The Second Affiliated Hospital of Army Medical University, Chongqing 400037, China President Office Xinqiao Hospital and The Second Affiliated Hospital of Army Medical University Chongqing 400037 China

Abstract

Background

Effective management of volume overload is essential for improving the prognosis of heart failure (HF), which is often complicated by exacerbations and rehospitalisations. Psychosocial and behavioural factors significantly influence volume status. However, studies directly linking these factors to volume overload in patients with HF remain limited.

Aim

This study aimed to model the direct and indirect influences of social support, cognition, self-efficacy, consideration of future outcomes, and self-care on volume overload in patients with HF to guide volume management interventions.

Method

A cross-sectional study was conducted among 233 consecutively hospitalised patients with HF from a tertiary hospital in Chongqing, China (January–July 2023). Bioelectrical impedance analysis measured volume status, and psychosocial and behavioural variables were assessed using validated scales, including the Lubben Social Network Scale, Mini-Cog, General Self-Efficacy Scale, Consideration of Future Consequences Scale, and Self-Care of Heart Failure Index, Version 6.2 Behaviour Scale. Data were analysed using IBM SPSS Statistics, Version 26.0 and AMOS 24.0.

Results

Among the patients (mean age=66.49±12.49 years; 43.35% women; 61.8% New York Heart Association stage III), 71% experienced volume overload. Path analysis showed that volume overload (oedema index) was directly and negatively associated with self-care maintenance (β=−0.263; p<0.001), cognition (β=−0.202; p<0.001), and self-efficacy (β=−0.199; p<0.01). Indirect negative effects were observed for social support (β=−0.203; p<0.001), self-care confidence (β=−0.090; p<0.001), and consideration of future outcomes (β=−0.057; p<0.001).

Conclusions

Factors such as social support, cognitive functioning, self-efficacy, future considerations, and self-care are significant contributors to the vulnerability of patients with HF to volume overload. This underscores the necessity for multifaceted interventions aimed at improving the prognosis of patients with HF.

Il testo completo di questo articolo è disponibile in PDF.

Keywords : Heart failure, Volume load, Social support, Cognitive impairment, Self-efficacy, Self-care


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Vol 35 - N° 4

P. 475-485 - aprile 2026 Ritorno al numero
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