Retinoic acid metabolism - 02/09/11
Doi : 10.1067/mjd.2001.113715
Abstract |
The tissue distribution of retinoic acid (RA) throughout development is highly restricted, defined by the expression patterns of enzymes involved in RA synthesis and catabolism. Presented is a summary of recent research that examines the role of some of the enzymes involved in RA distribution, particularly those involved in RA catabolism (P450RAI). These latter enzymes protect against premature exposure to RA, and the implications of these findings are discussed. (J Am Acad Dermatol 2001;45:S136-42.)
Il testo completo di questo articolo è disponibile in PDF. | Supported by the Medical Research Council of Canada and the National Cancer Institute of Canada. |
© 2001
The American Academy of Dermatology, Inc.. Pubblicato da Elsevier Masson SAS. Tutti i diritti riservati.
Vol 45 - N° 5
P. S136-S142 - novembre 2001 Ritorno al numero
Articolo precedente
- Cellular metabolism and actions of 13-cis-retinoic acid
- William S. Blaner
- Interaction of isotretinoin with endogenous retinoids
- Hans Törmä
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