Oral mucous membrane contact dermatitis (or contact stomatitis) is relatively rare. In general, the mucosa is more resistant to primary irritants, and is not as readily sensitized as the skin. The oral mucosa is also constantly bathed in saliva, which washes sensitizers from the mucosal surface and prevents adequate contact. Furthermore, abundant mucosal vasculature allows for rapid absorption and clearing of allergens. Nevertheless, contact reactions can occur on the oral mucous membrane. Contact sensitivity has been described as a factor in recurrent oral ulceration<sup>32 Jolly M., Moule A.J., Freeman S. Amalgam related chronic ulceration of oral mucosa Br Dent J 1986 ;  160 : 434-437  [cross-ref]

Cliccare qui per andare alla sezione Riferimenti, 43 Nolan A., Lamey P.-J., Milliken K.A. , e al. Recurrent aphthous ulceration and food sensitivity J Oral Pathol Med 1991 ;  20 : 473-475  [cross-ref]

Cliccare qui per andare alla sezione Riferimenti</sup> and oral lichenoid reactions.<sup>52 Todd P., Garioch J., Lamey P.-J. , e al. Patch testing in lichenoid reactions of the mouth Contact Dermatitis 1990 ;  23 : 300-301

Cliccare qui per andare alla sezione Riferimenti</sup> As with other types of contact dermatitis, allergic contact dermatitis may be difficult to distinguish from irritant contact dermatitis, and it may also mimic oral changes of vitamin deficiency, certain anemias, uremic stomatitis, and candidiasis.<sup>18 Fisher A.A. Contact stomatitis Dermatol Clinic 1987 ;  5 : 4:709-4:717

Cliccare qui per andare alla sezione Riferimenti</sup> Although the prevalence of allergic contact sensitivity in the mouth is unknown, a number of substances have been reported to cause oral symptoms.