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Intellectual Disability in Children with Attention Deficit Hyperactivity Disorder - 22/08/13

Doi : 10.1016/j.jpeds.2013.02.043 
Alka Ahuja, MRCPsych 1, 2, , Joanna Martin, BSc (Hons) 2, 3, , Kate Langley, PhD 2, 3, , Anita Thapar, FRCPsych, FMedSci, PhD 2, 3
1 Ty Bryn Unit, St Cadocs Hospital, Newport, United Kingdom 
2 Child and Adolescent Psychiatry Section, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, United Kingdom 
3 Medical Research Council Center for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff, United Kingdom 

Reprint requests: Kate Langley, PhD, Cardiff University School of Medicine, Department of Psychological Medicine, 4th Floor Main Building, Heath Park, Cardiff CF14 4XN, UK.

Abstract

Objective

To determine whether children with attention deficit hyperactivity disorder (ADHD) and mild intellectual disability (ID) are a clinically distinct ADHD subgroup.

Study design

This was a cross-sectional study comparing clinical characteristics (ADHD subtypes, total number of symptoms, and rates of common comorbidities) between children with ADHD and mild ID and those with ADHD and IQ test scores >70, and also between children with ADHD and ID and a general population sample of children with ID alone. The sample comprised a clinical sample of children with ADHD with ID (n = 97) and without ID (n = 874) and a general population sample of children with ID and without ADHD (n = 58).

Results

After correcting for multiple statistical tests, no differences were found between the 2 ADHD groups on any measure except the presence of conduct disorder (CD) symptoms and diagnoses. Children with ADHD and ID had higher rates of both (OR, 2.38; 95% CI, 1.71-3.32 and OR, 2.69; 95% CI, 1.69-4.28, respectively). Furthermore, children with ADHD and ID had significantly higher rates of oppositional defiant disorder (OR, 5.54; 95% CI, 2.86-10.75) and CD (OR, 13.66; 95% CI, 3.25-57.42) symptoms and a higher incidence of oppositional defiant disorder diagnoses (OR, 30.99; 95% CI, 6.38-150.39) compared with children with ID without ADHD.

Conclusion

Children with ADHD and mild ID appear to be clinically typical of children with ADHD except for more conduct problems. This finding has implications for clinicians treating these children in terms of acknowledging the presence and impact of ADHD symptoms above and beyond ID and dealing with a comorbid CD.

Il testo completo di questo articolo è disponibile in PDF.

Keyword : ADHD, ALSPAC, ASD, CAPA, CD, CNV, DSM-III-R, DSM-IV, ID, ODD


Mappa


 This is an open access article under the CC BY license (3.0/).
 Clinical ADHD sample was funded by the Baily Thomas Charitable Trust, Action Medical Research, and the Wellcome Trust. The ALSPAC sample was funded by the UK Medical Research Council, the Wellcome Trust (092731), and the University of Bristol. The authors declare no conflicts of interest.


© 2013  The Authors. Pubblicato da Elsevier Masson SAS. Tutti i diritti riservati.
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