Bleeding is one of the most important complications of endoscopic polipectomy. It may occur during the procedure or some hours or days later. The risk of bleeding is greater in some patients due to the size or shape of the lesion, its location, association of any kind of coagulation disturbance, drugs used by the patient, etc. The aim of this study is to describe a new polipectomy technique (for pedunculated polyps), with previous ligation of the polyp pedicle, using a pre tied and pre cut loop to avoid post polipectomy hemorrhage. During colonoscopy a metallic guide with a loop is passed through the biopsy channel and applied to the pedicle of the polyp. This loop is made using a nylon string where a Roeder knot is previously applied. The fixed limb of this line is partially sectioned, in order to permit its rupture after the knot is firmly tied. Right after that, a conventional polipectomy with a wire snare is performed above the loop ligation. So far, we have used this technique in only five patients with no complications.We believe that this new technique may represent an important help to avoid major bleeding in selected patients.