Endoscopic submucosal dissection for colorectal lateral spreading tumors larger than 10 cm: Is it feasible? - 23/02/15
Abstract |
Background |
Colorectal endoscopic submucosal dissection (ESD) was applied to lesions, such as giant colorectal lateral spreading tumors (LSTs) > 10 cm, by an expert ESD endoscopist despite several limitations, such as a relatively high perforation rate and high technical difficulty.
Objective |
To investigate the feasibility and safety of ESD for giant colorectal LSTs ≥ 10 cm.
Design |
Retrospective study.
Setting |
Tertiary-care center.
Patients |
A total of 163 patients underwent colorectal ESD between 2009 and 2014 by a single expert ESD endoscopist at Gangnam Severance Hospital, Seoul, Korea. Among them, 9 patients had giant colorectal LSTs ≥ 10 cm.
Interventions |
Review of records.
Main Outcome Measurements |
Clinicopathologic factors and oncologic outcome associated with ESD between giant colorectal LSTs and others.
Results |
Colorectal LSTs ≥ 10 cm were classified as giant colorectal LSTs. Nine giant colorectal LST lesions were localized to the following regions: descending colon (n = 1), sigmoid colon (n = 1), and rectum (n = 7). The average maximal diameter of giant colorectal LSTs was 120.8 mm, and the procedure time was 270.0 minutes. Two lesions were of the whole nodular type, and 7 were focal nodular lesions. The en bloc and curative resection rates for ESD for giant colorectal LSTs were 88.9% and 100%, respectively. The adverse event rate was 44.4%. No strictures, local recurrences, or distant metastases occurred over a mean follow-up period of 27.1 months.
Limitations |
Retrospective, single-center study.
Conclusions |
ESD of giant colorectal LSTs appears to be a feasible and curative treatment, even though it is associated with a higher adverse event rate, higher degree of technical difficulty, and longer procedure time.
Il testo completo di questo articolo è disponibile in PDF.Abbreviations : ESD, LST
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| DISCLOSURE: All authors disclosed no financial relationships relevant to this publication. |
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| If you would like chat with an author of this article, you may contact Dr Youn at dryoun@yuhs.ac. |
Vol 81 - N° 3
P. 614-620 - marzo 2015 Ritorno al numero
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