Sommario

• • ·Editorial Board

    Pagina :i

    

• Review Articles

  • ·Effective long-term solution to therapeutic remission in Inflammatory Bowel Disease: Role of Azathioprine

    Pagina :8-14

    Lyla Adam, Alisa Phulukdaree, Prashilla Soma

    Riassunto Riassunto Mappa Mappa  
  • ·Ginseng phytochemicals as therapeutics in oncology: Recent perspectives

    Pagina :52-63

    Fatima Majeed, Fozia Zahur Malik, Zaheer Ahmed, Asma Afreen, Muhammad Naveed Afzal, Nauman Khalid

    Riassunto Riassunto Mappa Mappa  
  • ·Immune cells involved in the pathogenesis of ankylosing spondylitis

    Pagina :198-204

    Alireza Rezaiemanesh, Mohsen Abdolmaleki, Kamal Abdolmohammadi, Hamideh Aghaei, Fatemeh Dadgar Pakdel, Yousef Fatahi, Narjes Soleimanifar, Mahdi Zavvar, Mohammad Hossein Nicknam

    Riassunto Riassunto Mappa Mappa  
  • ·Understanding of human ATP binding cassette superfamily and novel multidrug resistance modulators to overcome MDR

    Pagina :335-348

    Imran Shair Mohammad, Wei He, Lifang Yin

    Riassunto Riassunto Mappa Mappa  
  • ·Pharmacological values and therapeutic properties of black tea (Camellia sinensis): A comprehensive overview

    Pagina :521-531

    Muhammad Naveed, Jannat BiBi, Asghar Ali Kamboh, Imran Suheryani, Ihsanullah Kakar, Sarfaraz Ali Fazlani, Xia FangFang, Shahmir Ali kalhoro, Liang Yunjuan, Mohib Ullah Kakar, Mohamed E. Abd El-Hack, Ahmed E. Noreldin, Shi Zhixiang, Chen LiXia, Zhou XiaoHui

    Riassunto Riassunto Mappa Mappa  

• Original Articles

  • ·MiR-93-5p targeting PTEN regulates the NMDA-induced autophagy of retinal ganglion cells via AKT/mTOR pathway in glaucoma

    Pagina :1-7

    Rui Li, Yiping Jin, Qian Li, Xinghuai Sun, Haohao Zhu, Hongping Cui

    Riassunto Riassunto Mappa Mappa  
  • ·MicroRNA-204 protects H9C2 cells against hypoxia/reoxygenation-induced injury through regulating SIRT1-mediated autophagy

    Pagina :15-19

    Ruixia Qiu, Wen Li, Yunhai Liu

    Riassunto Riassunto Mappa Mappa  
  • ·Long non-coding RNA ENST01108 promotes carcinogenesis of glioma by acting as a molecular sponge to modulate miR-489

    Pagina :20-28

    Dawei Xu, Ruihua Liu, Lei Meng, Yi Zhang, Guangjian Lu, Pengju Ma

    Riassunto Riassunto Mappa Mappa   
  • ·Polyphenol-enriched extract of Rosa rugosa Thunb regulates lipid metabolism in diabetic rats by activation of AMPK pathway

    Pagina :29-35

    Liu Liu, Mireguli Yasen, Dan Tang, Jianping Ye, Haji Akber Aisa, Xuelei Xin

    Riassunto Riassunto Mappa Mappa  
  • ·Ghrelin attenuates ultraviolet B radiation-induced impairment in capacities of epidermal stem cells

    Pagina :36-41

    Yue-hui Wang, Cheng-kuan Sun, Xiang-lan Li, Yan Huang, Jing Sun

    Riassunto Riassunto Mappa Mappa  
  • ·Therapeutic efficacy of osthole against dinitrobenzene sulphonic acid induced-colitis in rats

    Pagina :42-51

    Hanan Khairy, Hanan Saleh, Abeer M. Badr, Mohamed-Assem S. Marie

    Riassunto Riassunto Mappa Mappa  
  • ·Icariside II attenuates myocardial fibrosis by inhibiting nuclear factor-κB and the TGF-β1/Smad2 signalling pathway in spontaneously hypertensive rats

    Pagina :64-71

    Shu Fu, Ye-Li Li, Yu-Ting Wu, Yun Yue, Zhi-Qiang Qian, Dan-Li Yang

    Riassunto Riassunto Mappa Mappa  
  • ·miR-145 overexpression triggers alteration of the whole transcriptome and inhibits breast cancer development

    Pagina :72-82

    Peng Ye, Yu Shi, Nairui An, Qian Zhou, Juan Guo, Xinghua Long

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  • ·Annona muricata Linn. leaf as a source of antioxidant compounds with in vitro antidiabetic and inhibitory potential against α-amylase, α-glucosidase, lipase, non-enzymatic glycation and lipid peroxidation

    Pagina :83-92

    Allisson Benatti Justino, Natália Carnevalli Miranda, Rodrigo Rodrigues Franco, Mário Machado Martins, Neide Maria da Silva, Foued Salmen Espindola

    Riassunto Riassunto Mappa Mappa   
  • ·Ginsenoside Rb2 promotes glucose metabolism and attenuates fat accumulation via AKT-dependent mechanisms

    Pagina :93-100

    Shanshan Dai, Yilian Hong, Jing Xu, Yi Lin, Qiya Si, Xuejiang Gu

    Riassunto Riassunto Mappa Mappa  
  • ·LncRNA Uc.173 is a key molecule for the regulation of lead-induced renal tubular epithelial cell apoptosis

    Pagina :101-107

    Jiabi Qin, Huacheng Ning, Yao Zhou, Yue Hu, Bo Huang, Yue Wu, Ruixue Huang

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  • ·Tumor suppressive ZBTB4 inhibits cell growth by regulating cell cycle progression and apoptosis in Ewing sarcoma

    Pagina :108-115

    Yongxin Yu, Ruguo Shang, Yunzhou Chen, Jiehua Li, Zhichao Liang, Jianwei Hu, Kai Liu, Chao Chen

    Riassunto Riassunto Mappa Mappa   
  • ·Psychotomimetic-like behavioral effects of memantine in the mouse

    Pagina :116-123

    Nobue Kitanaka, Junichi Kitanaka, F. Scott Hall, Yoshiro Kubota, Yumi Mimura, Sayaka Ogura, Yukiya Okada, George R. Uhl, Motohiko Takemura

    Riassunto Riassunto Mappa Mappa  
  • ·HG30, a tetrahydroanthraquinone compound isolated from the roots of Prismatomeris connate, induces apoptosis in human non-small cell lung cancer cells

    Pagina :124-131

    Shixiu Feng, Zhenzhen Wang, Min Zhang, Xiaohui Zhu, Zhanjun Ren

    Riassunto Riassunto Mappa Mappa   
  • ·Differential expression of the receptors for thyroid hormone, thyroid stimulating hormone, vitamin D and retinoic acid and extracellular signal-regulated kinase in uterus of rats under influence of sex-steroids

    Pagina :132-141

    Abu Sadat Md Sayem, Nelli Giribabu, Kamarulzaman Karim, Lay Khiang Si, Sekaran Muniandy, Naguib Salleh

    Riassunto Riassunto Mappa Mappa  
  • ·Gentiopicroside inhibits RANKL-induced osteoclastogenesis by regulating NF-κB and JNK signaling pathways

    Pagina :142-146

    Fangqing Chen, Lin Xie, Ran Kang, Rongrong Deng, Zhipeng Xi, Daoxi Sun, Jin Zhu, Liming Wang

    Riassunto Riassunto Mappa Mappa  
  • ·Antihypertensive and antioxidant effects of protocatechuic acid in deoxycorticosterone acetate-salt hypertensive rats

    Pagina :147-155

    Leila Safaeian, Reyhaneh Emami, Valiollah Hajhashemi, Zahra Haghighatian

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  • ·Shengmai San-derived herbal prevents the development of a vulnerable substrate for atrial fibrillation in a rat model of ischemic heart failure

    Pagina :156-167

    Jin Ma, Shiyu Ma, Chunxia Yin, Huanlin Wu

    Riassunto Riassunto Mappa Mappa  
  • ·EIF5A1 promotes epithelial ovarian cancer proliferation and progression

    Pagina :168-175

    Jing Zhang, Xiao Li, Xiaorui Liu, Fuju Tian, Weihong Zeng, Xiaowei Xi, Yi Lin

    Riassunto Riassunto Mappa Mappa   
  • ·Astragalus polysaccharide enhanced antitumor effects of Apatinib in gastric cancer AGS cells by inhibiting AKT signalling pathway

    Pagina :176-183

    Jun Wu, Junxian Yu, Jing Wang, Chenguang Zhang, Kun Shang, Xiaojun Yao, Bangwei Cao

    Riassunto Riassunto Mappa Mappa  
  • ·MicroRNA-519d inhibits proliferation and induces apoptosis of human hypertrophic scar fibroblasts through targeting Sirtuin 7

    Pagina :184-190

    Xiaoqian Zhou, Yidun Xie, Houan Xiao, Xudong Deng, Yu Wang, Liyuan Jiang, Chen Liu, Rui Zhou

    Riassunto Riassunto Mappa Mappa   
  • ·Silybum marianum oil attenuates hepatic steatosis and oxidative stress in high fat diet-fed mice

    Pagina :191-197

    Shu Yun Zhu, Ning Jiang, Jing Yang, Jie Tu, Yue Zhou, Xiang Xiao, Ying Dong

    Riassunto Riassunto Mappa Mappa  
  • ·PSMB8 regulates glioma cell migration, proliferation, and apoptosis through modulating ERK1/2 and PI3K/AKT signaling pathways

    Pagina :205-212

    Bing-ya Yang, Jing-wei Song, Hong-zhi Sun, Ji-cheng Xing, Zhi-hui Yang, Chang-yong Wei, Tuo-ye Xu, Zhen-nan Yu, Ye-nan Zhang, Ying-fan Wang, Hao Chang, Zhi-peng Xu, Min Hou, Min-jun Ji, Yan-song Zhang

    Riassunto Riassunto Mappa Mappa  
  • ·Protective effects of Punica granatum (pomegranate) peel extract on concanavalin A-induced autoimmune hepatitis in mice

    Pagina :213-220

    Tingting Wang, Ruoting Men, Mingxing Hu, Xiaoli Fan, Xiaoxue Yang, Xiaojun Huang, Tinghong Ye, Li Yang

    Riassunto Riassunto Mappa Mappa  
  • ·Oridonin inhibits oral cancer growth and PI3K/Akt signaling pathway

    Pagina :226-232

    Jing Yang, Xianyue Ren, Liping Zhang, Yuanyuan Li, Bin Cheng, Juan Xia

    Riassunto Riassunto Mappa Mappa  
  • ·SPC25 upregulation increases cancer stem cell properties in non-small cell lung adenocarcinoma cells and independently predicts poor survival

    Pagina :233-239

    Jingxia Chen, Hongfen Chen, Hanbing Yang, Huizhen Dai

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  • ·RETRACTED: Long noncoding RNA maternally expressed gene 3 knockdown alleviates lipopolysaccharide-induced inflammatory injury by up-regulation of miR-203 in ATDC5 cells

    Pagina :240-249

    Zhaolin Wang, Xiaohua Chi, Liping Liu, Yaqun Wang, Xiaoyan Mei, Yan Yang, Tanghong Jia

    
  • ·LncRNA-LET inhibits cell viability, migration and EMT while induces apoptosis by up-regulation of TIMP2 in human granulosa-like tumor cell line KGN

    Pagina :250-256

    Qingfang Han, Wenke Zhang, Jinlai Meng, Li Ma, Aihua Li

    Riassunto Riassunto Mappa Mappa  
  • ·Sirtuin7 has an oncogenic potential via promoting the growth of cholangiocarcinoma cells

    Pagina :257-266

    Wenzhi Li, Zhe Sun, Chen Chen, Lin Wang, Zhimin Geng, Jie Tao

    Riassunto Riassunto Mappa Mappa  
  • ·Efficacy and safety of combined low doses of either diclofenac or celecoxib with gabapentin versus their single high dose in treatment of neuropathic pain in rats

    Pagina :267-274

    Mohamed A. Ibrahim, Walaa Yehia Abdelzaher, Remon R. Rofaeil, Soha Abdelwahab

    Riassunto Riassunto Mappa Mappa  
  • ·Anti-migraine and anti-depression activities of Tianshu capsule by mediating Monoamine oxidase

    Pagina :275-281

    Xiaoping Sun, Fangfang Zhu, Jun Zhou, Xiujuan Chang, Liang Li, Hanfei Hu, Zhenzhong Wang, Wei Xiao

    Riassunto Riassunto Mappa Mappa  
  • ·6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid attenuates colon carcinogenesis via blockade of IL-6 mediated signals

    Pagina :282-295

    Priyanka Mishra, Vinit Raj, Archana S. Bhadauria, Ashok K Singh, Amit Rai, Pranesh Kumar, Amit K Keshari, Arnab De, Amalesh Samanta, Umesh Kumar, Dinesh Kumar, Biswanath Maity, Sneha Nath, Anand Prakash, Kausar M. Ansari, Sudipta Saha

    Riassunto Riassunto Mappa Mappa   
  • ·Regulation of JAK2/STAT3 and NF-κB signal transduction pathways; Veronica polita alleviates dextran sulfate sodium-induced murine colitis

    Pagina :296-303

    Md Rashedunnabi Akanda, Hyeon-Hwa Nam, Weishun Tian, Anowarul Islam, Byung-Kil Choo, Byung-Yong Park

    Riassunto Riassunto Mappa Mappa  
  • ·Ferulic acid protects lipopolysaccharide-induced acute kidney injury by suppressing inflammatory events and upregulating antioxidant defenses in Balb/c mice

    Pagina :304-315

    Salma Mukhtar Mir, Halley Gora Ravuri, Raj Kumar Pradhan, Sairam Narra, Jerald Mahesh Kumar, Madhusudana Kuncha, Sanjit Kanjilal, Ramakrishna Sistla

    Riassunto Riassunto Mappa Mappa  
  • ·MicroRNA signature of regulatory T cells in health and autoimmunity

    Pagina :316-323

    Mehdi Soltanzadeh-Yamchi, Mehdi Shahbazi, Saeed Aslani, Mousa Mohammadnia-Afrouzi

    Riassunto Riassunto Mappa Mappa  
  • ·Evaluation of the anti-hypertensive effect of Tengfu Jiangya tablet by combination of UPLC-Q-exactive-MS-based metabolomics and iTRAQ-based proteomics technology

    Pagina :324-334

    Yanpeng Tian, Feng Jiang, Yunlun Li, Haiqiang Jiang, Yanjun Chu, Lijuan Zhu, Weixing Guo

    Riassunto Riassunto Mappa Mappa   
  • ·Micro RNA-1298 opposes the effects of chronic oxidative stress on human trabecular meshwork cells via targeting on EIF4E3

    Pagina :349-357

    Wu Ruibin, Xiaowei Zheng, Jiaying Chen, Xinyi Zhang, Xiayin Yang, Yuxian Lin

    Riassunto Riassunto Mappa Mappa  
  • ·RETRACTED: Activation of PPARγ mediates icaritin-induced cell cycle arrest and apoptosis in glioblastoma multiforme

    Pagina :358-366

    Yongji Liu, Ling Shi, Yuan Liu, Peng Li, Guoping Jiang, Xiaoning Gao, Yongbin Zhang, Chuanwu Jiang, Weiping Zhu, Hongxing Han, Fang Ju

    Riassunto Riassunto
  • ·Molecular chemoprevention by morin – A plant flavonoid that targets nuclear factor kappa B in experimental colon cancer

    Pagina :367-373

    Sharada H. Sharma, Jayasurya Suresh Kumar, David Raj Chellappan, Sangeetha Nagarajan

    Riassunto Riassunto Mappa Mappa  
  • ·POU5F1B promotes hepatocellular carcinoma proliferation by activating AKT

    Pagina :374-380

    Yaozhen Pan, Lei Zhan, Ling Chen, Hong Zhang, Chengyi Sun, Chungen Xing

    Riassunto Riassunto Mappa Mappa  
  • ·The vasodilatory effect of allopurinol mediates its antihypertensive effect: Effects on calcium movement and cardiac hemodynamics

    Pagina :381-387

    Hany M. El-Bassossy, Mona F Mahmoud, Basma G Eid

    Riassunto Riassunto Mappa Mappa  
  • ·The sedative activity of flavonoids from Passiflora quadrangularis is mediated through the GABAergic pathway

    Pagina :388-393

    Andressa Corneo Gazola, Geison Modesti Costa, Silvana Maria Zucolotto, Leonardo Castellanos, Freddy Alejandro Ramos, Thereza Christina Monteiro de Lima, Eloir Paulo Schenkel

    Riassunto Riassunto Mappa Mappa   
  • ·Apocynum venetum leaf extract reverses depressive-like behaviors in chronically stressed rats by inhibiting oxidative stress and apoptosis

    Pagina :394-406

    Xiangting Li, Ting Wu, Zhonghai Yu, Tingting Li, Jingsi Zhang, Zhennian Zhang, Min Cai, Wen Zhang, Jun Xiang, Dingfang Cai

    Riassunto Riassunto Mappa Mappa  
  • ·EFLDO induces apoptosis in hepatic cancer cells by caspase activation in vitro and suppresses tumor growth in vivo

    Pagina :407-416

    Yan-bo Qu, Zhi-xin Liao, Chao Liu, Xin-zhu Wang, Jing Zhang

    Riassunto Riassunto Mappa Mappa  
  • ·Two sesquiterpene aminoquinones protect against oxidative injury in HaCaT keratinocytes via activation of AMPKα/ERK-Nrf2/ARE/HO-1 signaling

    Pagina :417-425

    Li Liu, Wei Wu, Jing Li, Wei-Hua Jiao, Li-Yun Liu, Jie Tang, Lei Liu, Fan Sun, Bing-Nan Han, Hou-Wen Lin

    Riassunto Riassunto Mappa Mappa   
  • ·Intraperitoneal administration of mesenchymal stem cells ameliorates acute dextran sulfate sodium-induced colitis by suppressing dendritic cells

    Pagina :426-432

    Aleksandar Nikolic, Bojana Simovic Markovic, Marina Gazdic, C. Randall Harrell, Crissy Fellabaum, Nemanja Jovicic, Valentin Djonov, Nebojsa Arsenijevic, Miodrag L Lukic, Miodrag Stojkovic, Vladislav Volarevic

    Riassunto Riassunto Mappa Mappa  
  • ·Effects of sunitinib targeted chemotherapy on the osseointegration of titanium implants

    Pagina :433-440

    Badr Al-Jandan, Hesham F. Marei, Hatem Abuohashish, Osama Zakaria, Haytham Al-Mahalawy

    Riassunto Riassunto Mappa Mappa  
  • ·Quercetin enhances chemotherapeutic effect of doxorubicin against human breast cancer cells while reducing toxic side effects of it

    Pagina :441-447

    Shizheng Li, Song Yuan, Qian Zhao, Bo Wang, Xiuyan Wang, Kun Li

    Riassunto Riassunto Mappa Mappa  
  • ·MiR17 improves insulin sensitivity through inhibiting expression of ASK1 and anti-inflammation of macrophages

    Pagina :448-454

    Chen Zhang, Dong Qian, Hongzhi Zhao, Nan Lv, Pei Yu, Zhe Sun

    Riassunto Riassunto Mappa Mappa  
  • ·Cardioprotective effect of resistance training and Crataegus oxyacantha extract on ischemia reperfusion–induced oxidative stress in diabetic rats

    Pagina :455-460

    Kamal Ranjbar, Ebrahim Zarrinkalam, Iraj Salehi, Alireza Komaki, Bayan Fayazi

    Riassunto Riassunto Mappa Mappa  
  • ·Evaluation of antidiabetic potential of steroidal alkaloid of Sarcococca saligna

    Pagina :461-466

    Naeem Ullah Jan, Amjad Ali, Bashir Ahmad, Naveed Iqbal, Achyut Adhikari, Abid Ali, Safdar Ali, Azra Jahan, Hamid Ali, Ijaz Ali, Anwar Ullah, Syed Ghulam Musharraf

    Riassunto Riassunto Mappa Mappa  
  • ·Chlorogenic acid attenuates glucotoxicity in H9c2 cells via inhibition of glycation and PKC α upregulation and safeguarding innate antioxidant status

    Pagina :467-477

    M.R. Preetha Rani, Nair Anupama, Mohan Sreelekshmi, K.G. Raghu

    Riassunto Riassunto Mappa Mappa  
  • ·Angiogenic potential of YKL-40 in the dynamics of tumor niche

    Pagina :478-485

    Ayda Pouyafar, Milad Zadi Heydarabad, Soltanali Mahboob, Ahad Mokhtarzadeh, Reza Rahbarghazi

    Riassunto Riassunto Mappa Mappa  
  • ·Bavachin induces the apoptosis of multiple myeloma cell lines by inhibiting the activation of nuclear factor kappa B and signal transducer and activator of transcription 3

    Pagina :486-494

    Tomoya Takeda, Masanobu Tsubaki, Yoshika Tomonari, Keishi Kawashima, Tatsuki Itoh, Motohiro Imano, Takao Satou, Shozo Nishida

    Riassunto Riassunto Mappa Mappa  
  • ·Oral administration effects of β-d-mannuronic acid (M2000) on Th17 and regulatory T cells in patients with ankylosing spondylitis

    Pagina :495-500

    Mohammad Javad Fattahi, Hossein Ahmadi, Fahimeh Jafarnezhad-Ansariha, Seyed Shahabeddin Mortazavi-Jahromi, Bernd H.A. Rehm, Salvatore Cuzzocrea, Hidenori Matsuo, Abbas Mirshafiey

    Riassunto Riassunto Mappa Mappa  
  • ·A novel limonin derivate modulates inflammatory response by suppressing the TLR4/NF-κB signalling pathway

    Pagina :501-508

    Shuwei Jin, Jingqi Wang, Siying Chen, Aidou Jiang, Meiling Jiang, Yourui Su, Wei Yan, Yungen Xu, Guoqing Gong

    Riassunto Riassunto Mappa Mappa   
  • ·Low expression of GFI-1 Gene is associated with Panobinostat-resistance in acute myeloid leukemia through influencing the level of HO-1

    Pagina :509-520

    Bingqing Cheng, Sishi Tang, Nana Zhe, Dan Ma, Kunlin Yu, Danna Wei, Zheng Zhou, Tingting Lu, Jishi Wang, Qin Fang

    Riassunto Riassunto Mappa Mappa   
  • ·Clarifying of the potential mechanism of Sinisan formula for treatment of chronic hepatitis by systems pharmacology method

    Pagina :532-550

    Zhiming Shu, Wang He, Mohamed Shahen, Zihu Guo, Jia Shu, Tiantian Wu, Xiaoyu Bian, Akhtar Hussain Shar, Mayada Ragab Farag, Mahmoud Alagawany, Chaobin Liu

    Riassunto Riassunto Mappa Mappa  
  • ·Methylphenidate clinically oral doses improved brain and heart glutathione redox status and evoked renal and cardiac tissue injury in rats

    Pagina :551-563

    Sara Loureiro-Vieira, Vera Marisa Costa, José Alberto Duarte, Margarida Duarte-Araújo, Salomé Gonçalves-Monteiro, Bastos Maria de Lourdes, Félix Carvalho, João Paulo Capela

    Riassunto Riassunto Mappa Mappa  
  • ·Therapeutic effects of Saussurea involucrata injection against severe acute pancreatitis- induced brain injury in rats

    Pagina :564-574

    Xiaohong Wang, Lei Chu, Chun Liu, Ronglong Wei, Xianglong Xue, Yuefen Xu, Mengjie Wu, Qing Miao

    Riassunto Riassunto Mappa Mappa  
  • ·The protective effect of astaxanthin against cisplatin-induced nephrotoxicity in rats

    Pagina :575-582

    Gorkem Akca, Huseyin Eren, Levent Tumkaya, Tolga Mercantepe, Mustafa Ozan Horsanali, Ezgi Deveci, Eyup Dil, Adnan Yilmaz

    Riassunto Riassunto Mappa Mappa  
  • ·An aqueous extract of Nomura’s jellyfish ameliorates inflammatory responses in lipopolysaccharide-stimulated RAW264.7 cells and a zebrafish model of inflammation

    Pagina :583-589

    Su Jung Hwang, Eun-Young Ahn, Youmie Park, Hyo-Jong Lee

    Riassunto Riassunto Mappa Mappa  

• Short Communication

  • ·Swertisin ameliorates diabetes by triggering pancreatic progenitors for islet neogenesis in Streptozotocin treated BALB/c mice

    Pagina :221-225

    Abhay Srivastava, Nidheesh Dadheech, Mitul Vakani, Sarita Gupta

    Riassunto Riassunto Mappa Mappa