Sommario

• • ·Editorial Board

    Articolo :118738

    

• Review Articles

  • ·Harnessing nanotechnology for improving the druggability of opium poppy-derived pharmaceutical benzylisoquinoline alkaloids: A review

    Articolo :118557

    Zahra Aghaali, Mohammad Reza Naghavi

    Riassunto Riassunto Mappa Mappa  
  • ·Wharton’s jelly mesenchymal stem cells (WJ-MSCs), a “Holy Grail” in tissue bioengineering and reconstructive medicine

    Articolo :118570

    Tomasz Górnicki, Małgorzata Józkowiak, Krzysztof Data, Dominika Domagała, Julia Niebora, Ewa Okowińska, Anna Kłopot, Magdalena Kulus, Artur Bryja, Sławomir Woźniak, Adam Kamiński, Piotr Chmielewski, Aleksandra Górska, Aleksandra Partyńska, Teresa Wysocka, Marek Spaczyński, Hanna Piotrowska-Kempisty, Piotr Dzięgiel, Paul Mozdziak, Bogusław Czerny, Bartosz Kempisty

    Riassunto Riassunto Mappa Mappa  
  • ·Bacteria-mediated cancer therapy (BMCT): Therapeutic applications, clinical insights, and the microbiome as an emerging hallmark of cancer

    Articolo :118559

    Mrunali Jayaprakash, Deekshit Vijaya Kumar, Gunimala Chakraborty, Anirban Chakraborty, Vinod Kumar

    Riassunto Riassunto Mappa Mappa  
  • ·Neutrophils and NETosis in Alzheimer’s disease: Unraveling pathogenic mechanisms and novel therapeutic targets

    Articolo :118568

    Sara Chavoshinezhad, Elmira Beirami, Esmael Izadpanah

    Riassunto Riassunto Mappa Mappa  
  • ·Metabolites as potential tools for the diagnosis and treatment of saccular intracranial aneurysms

    Articolo :118567

    Xiaojie Ren, Zhaomeng Wang, Yukun Xiang, Yiwen Fu, Jing Xue, Lemin Zheng

    Riassunto Riassunto Mappa Mappa  
  • ·Corneal endothelial cells decline – A review of recent findings from molecular and clinical research

    Articolo :118564

    Dominika Domagała, Maria Muzyka-Woźniak, Natalia Penciak, Julia Niebora, Sławomir Woźniak

    Riassunto Riassunto Mappa Mappa  
  • ·Pathophysiological mechanisms underlying diarrhea across generations of EGFR-TKIs: The role of ERBB signaling and potential therapies

    Articolo :118562

    Jutharat Ariyadamrongkwan, Chatchai Muanprasat

    Riassunto Riassunto Mappa Mappa  
  • ·Unravelling Thymidine phosphorylase: Mechanisms and multifunctional impact on cardiovascular system – from bench to bedside

    Articolo :118577

    Damian Gajecki, Liliana Kiczak, Jacek Majda, Waldemar Banasiak, Adrian Doroszko

    Riassunto Riassunto Mappa Mappa  
  • ·Factors of bias in spheroid-based drug screening: Fabrication method, spheroid size, and cell viability

    Articolo :118597

    Sunghan Lee, Jiseok Lim, Bongseop Kwak

    Riassunto Riassunto Mappa Mappa  
  • ·Trimethylamine N-Oxide (TMAO) and cancer risk: Insights into a possible link

    Articolo :118592

    Biki Saha, Antara Banerjee, Rupak Pathak, Asim K. Duttaroy, Surajit Pathak

    Riassunto Riassunto Mappa Mappa  
  • ·ZNRF2 integrates ubiquitination-driven ferroptosis and mitochondrial quality control in renal ischemia–reperfusion injury

    Articolo :118584

    Kangyu Wang, Yun Deng, Changhong Xu, Rui Yan, Hao Wang, Yalong Zhang, Jiangwei Man, Li Yang

    Riassunto Riassunto Mappa Mappa  
  • ·Exosomes in Alzheimer’s disease: From pathogenesis to therapeutics—A comprehensive review of diagnostic and drug delivery applications

    Articolo :118548

    Mona Shahlaei, Hamed Afkhami, Amirhossein Ahmadieh-Yazdi, Seyed Hashem Mirmazloumi, Seyedeh Saeideh Sahraei, Mohammad Akbari, Piao Yang, Hamed Manoochehri, Hamid Tanzadehpanah, Hanie Mahaki, Aravind Sundararaman, Sreedivya Mohan, Mohsen Sheykhhasan, Sharafaldin Al-Musawi, Paola Dama

    Riassunto Riassunto Mappa Mappa  
  • ·Current status and future perspectives of drug delivery systems loaded with baicalein and baicalin in cancer therapy

    Articolo :118589

    Amirreza Nazemiyeh, Samar Mahari, Nima Nazemiyeh, Hossein Abdolmohammadzadeh, Zahra Farshbaf, Athena Rajabzadeh, Somayeh Vandghanooni, Hossein Nazemiyeh, Morteza Eskandani

    Riassunto Riassunto Mappa Mappa  
  • ·Fighting cancer smarter: Using hydrogel delivery systems to target chemokines

    Articolo :118601

    Hossein Khorramdelazad, Pegah Yaraghi, Zahra Shirzad, Armin Boroumand, Reyhaneh Arfaei, Abbas Kheyri, Mohammad Keshavarz, Fatemeh Daj, Maryam Keykhaee

    Riassunto Riassunto Mappa Mappa  
  • ·Proteasome-mediated ubiquitination in neural regeneration

    Articolo :118563

    Huanyi Li, Yiwen Hu, Meili Cheng, Jialin Wang, Mingxia Zhao, Bolun Cao, Yulu Zhao, Jingjing Jiang

    Riassunto Riassunto Mappa Mappa  
  • ·Recent developments in bioconjugation: From strategies to design and clinical applications

    Articolo :118593

    Faezeh Samieipour, Hassan Dianat-Moghadam, Hossein Khanahmad

    Riassunto Riassunto Mappa Mappa  
  • ·Recent advances and clinical potential of hyaluronic acid methacrylate (HAMA)/ceramic composites in oral and dental regenerative therapies: A comprehensive review

    Articolo :118590

    Mohammad Golrokhian, Haleh Fakhimi Rezaei, Maryam Rezaeianjam, Bita Moslem, Kimia Naderpour, Amir Abbas Seraji

    Riassunto Riassunto Mappa Mappa  
  • ·Cognitive dysfunction in chemobrain: Molecular mechanisms and therapeutic implications

    Articolo :118581

    Hyung-Goo Kim, Mohammad Abdur Rashid, Michael Poleschuk, Faheem Ullah, Sang Hoon Lee, Sang Hoon Kim, Bo Qin, X.F. Steven Zheng, Mi-Hyeon Jang

    Riassunto Riassunto Mappa Mappa  
  • ·Nanofibers for paclitaxel delivery: A promising avenue for cancer therapy

    Articolo :118607

    Alireza Noori, Mojdeh Salehi Namini, Ehsaneh Azaryan, Mahshid Ataei, Nima Beheshtizadeh

    Riassunto Riassunto Mappa Mappa   
  • ·Immune cell dynamics and their role in cardiac injury: Mechanisms and therapeutic implications

    Articolo :118608

    Chunlei Liu, Rihan Wu, Hao Yang, Yongming Yao

    Riassunto Riassunto Mappa Mappa  
  • ·Targeting metabolic syndrome with ALIAmides: A novel multi-mechanistic approach

    Articolo :118611

    Irene Palenca, Maria Masulli, Sara Rurgo, Giovanni Sarnelli, Giuseppe Esposito

    Riassunto Riassunto Mappa Mappa  
  • ·Unraveling ferroptosis in infectious diseases: From basics, mechanistic pathways, and its dual role in the infections to potential therapeutic implications

    Articolo :118624

    Niloofar Kiaheyrati, Amir Mahdi Ghaffari Moaf, Maedeh Manzari, Ava Payravand, Samira Sabzi, Fatemeh Samiee-Rad, Abouzar Babaei

    Riassunto Riassunto Mappa Mappa  
  • ·The pathogenesis of metabolic dysfunction-associated steatotic liver disease and nucleoside reverse transcriptase inhibitors (NRTIs) -based HIV-antiretroviral regimens: A comprehensive narrative review

    Articolo :118633

    Marilize Horn, Nontobeko Gumede, Mlindeli Gamede

    Riassunto Riassunto Mappa Mappa  
  • ·Role of adrenergic receptors and their blocking in cancer research

    Articolo :118637

    Simona Gazova, Ladislav Klena, Kristina Galvankova, Petr Babula, Olga Krizanova

    Riassunto Riassunto Mappa Mappa  
  • ·The crosstalk of m6A modification and non-coding RNAs in ferroptosis regulation in human diseases

    Articolo :118626

    Ying Zhu, Meihuan Chen, Xinyuan Feng, Dahang Ye, Liangpu Xu, Hailong Huang

    Riassunto Riassunto Mappa Mappa  
  • ·RETRACTED: Branched-chain amino acids in bone health: From molecular mechanisms to therapeutic potential

    Articolo :118645

    Zhen Liang, Zhanpeng Su, Haina Yang, Jinchang Zheng, Xinyuan Wu, Min Huang, Litao Duan, Shaoru Chen, Bo Wei, Xingxing Fan, Sien Lin

    Riassunto Riassunto
  • ·Bee venom in pharmacology: Mechanistic insights from pro-inflammatory trigger to anti-inflammatory therapeutic agent

    Articolo :118636

    Sriwidodo Sriwidodo, Cecep Suhandi, Gofarana Wilar, Nasrul Wathoni

    Riassunto Riassunto Mappa Mappa  
  • ·Effect of colchicine in heart failure patients with metabolic syndrome: Focus on inflammatory mechanisms

    Articolo :118629

    Nan Xu, Shengjie Cheng, Quan Yuan

    Riassunto Riassunto Mappa Mappa  
  • ·Recent advances in the development of targeted drugs for hematopoietic progenitor kinase 1: An updated review

    Articolo :118683

    Zihan Song, Mingyue Zhang, Mingfei Wu, Chixiao Zhang, Wenhai Huang, Shenxin Zeng

    Riassunto Riassunto Mappa Mappa  
  • ·Stem cell-free therapy for healthy brain aging: Mechanisms, challenges, and prospects

    Articolo :118676

    Jahnavy Madhukar Joshi, Shweta Verma, Raviraja Neelavar Seetharam, Abhishek Kumar Singh

    Riassunto Riassunto Mappa Mappa  
  • ·Advances about the study of phycocyanin in the treatment of breast cancer: A review

    Articolo :118586

    Jiajia Yu, Liyun Sun, Liang Ji, Kaixin Wei, Xudong Chen, Jianhua Fan, Yingze Wei

    Riassunto Riassunto Mappa Mappa  
  • ·Perspectives of cannabis-based medicines in a view of pharmacokinetic studies of Δ9-THC and CBD in humans

    Articolo :118673

    Magdalena Kaszewska, Katarzyna Woźniczka, Katarzyna Sztormowska-Achranowicz, Agnieszka Mosińska, Václav Trojan, Patrik Schreiber, Nikolas Balog, Tomasz Bączek, Anna Roszkowska

    Riassunto Riassunto Mappa Mappa  
  • ·Neurologic complications of immune checkpoint inhibitors: A comprehensive review

    Articolo :118669

    Saeed Zivari Lashkajani, Yasaman Sadat Azad, Mohammad Taha Nami, Ali Darzi, Mahla shokouhfar, Sina Naddaf faizabadi, Maryam Diansaei, Komeil Aghazadeh-Habashi, Zahra Azimzadeh Tabrizi, Ahmad Ghorbani Vanan

    Riassunto Riassunto Mappa Mappa  
  • ·Spatial immune landscapes of the human placenta: Biomarkers and therapeutic insights in pregnancy disorders

    Articolo :118688

    Ning Zhang, Jing Li, Wenxue Ma, Jun Zhou

    Riassunto Riassunto Mappa Mappa  

• Original Articles

  • ·Obeticholic acid does not restore Western diet-induced alterations in hepatic mitochondrial respiration

    Articolo :118542

    Jan Melek, Pavla Staňková, Eva Peterová, Tumisang Edward Maseko, Veronika Špalková, Reem Matar, Ahmed Ibrahim, Moustafa Elkalaf, Miroslav Podhola, Alžběta Štefela, Zuzana Červinková, Petr Pávek, Otto Kučera

    Riassunto Riassunto Mappa Mappa   
  • ·Microbiota-derived butyrate potentiates MSLN CAR-T cell therapy by metabolic reprogramming and extracellular matrix remodeling

    Articolo :118560

    Jiannan Chen, Wenying Li, Lindong Yang, Jiayi Li, Shuai Wang, Zhengliang Chen, Shichu Xu, Mengru Wen, Junqing Liang, Zhigang Hu, Feiyan Pan, Lingfeng He, Lili Gu, Zhiqiang Wang, Haoyan Chen, Zhigang Guo

    Riassunto Riassunto Mappa Mappa   
  • ·Baicalin attenuates acetaminophen-induced acute liver injury through inhibiting TLR2-dependent neutrophil extracellular trap formation

    Articolo :118569

    Mohamed Hussein Osman, Chen Zhu, Yingxue Yang, Yucheng Wang, Junjie Xie, Jiawei Wu, Qinghua Wang

    Riassunto Riassunto Mappa Mappa   
  • ·Targeting RUNX3/PARP1 signaling ameliorates colorectal cancer cachexia

    Articolo :118561

    Abinash Swain, Pinaki Prasad Mahapatra, Abhishek Nirwan, Neelam Gupta, Arun Kumar, Rashi Saxena, Jaspreet Kaur, Shakil Ahmed, Durga Prasad Mishra

    Riassunto Riassunto Mappa Mappa   
  • ·Development and application of a multimatrix LC–MS/MS method for quantifying elexacaftor–tezacaftor–ivacaftor: Expanding therapeutic drug monitoring in cystic fibrosis from systemic circulation to airways and sweat

    Articolo :118558

    Matteo Mucci, Martina Colarelli, Pietro Ripani, Marta Di Nicola, Marianna Del Ciotto, Maria Di Sabatino, Francesca Collini, Mario Romano, Antonio Recchiuti

    Riassunto Riassunto Mappa Mappa   
  • ·Leriglitazone improves iron homeostasis and ferroptotic markers in frataxin-deficient dorsal root ganglia neurons

    Articolo :118553

    Marta Portillo-Carrasquer, Arabela Sanz-Alcázar, Fabien Delaspre, Maria Pazos-Gil, Luiza Oliveira-Jorge, Cristina Vergara, Laura Rodríguez-Pascau, Pilar Pizcueta, Jordi Tamarit, Joaquim Ros, Elisa Cabiscol

    Riassunto Riassunto Mappa Mappa   
  • ·TME-responsive nanoparticles co-targeting VCP, NETs, and dual immune checkpoints for immune revitalization in EGFR/PD-L1/CTLA-4–driven colorectal cancer

    Articolo :118565

    Yu-Li Lo, Hua-Ching Lin, Yaorong Lee, Hui-Yen Chuang, Tsui-Fen Chou

    Riassunto Riassunto Mappa Mappa   
  • ·Pentagalloyl glucose reverses chemoresistance in triple-negative breast cancer via EMT inhibition and miRNA modulation

    Articolo :118572

    Jiraporn Kantapan, Phattarawadee Innuan, Natsima Viriyaadhammaa, Nampeung Anukul, Imjai Chitapanarux, Nathupakorn Dechsupa

    Riassunto Riassunto Mappa Mappa   
  • ·Sexual dimorphism in vincristine-induced neuropathic pain, effect of prokineticin antagonism

    Articolo :118596

    Giada Amodeo, Giulia Galimberti, Roberta Lattanzi, Anna Teresa Brini, Valentina Onnis, Paola Sacerdote, Silvia Franchi

    Riassunto Riassunto Mappa Mappa   
  • ·Enhancing mood post-bariatric surgery: Associations of rosuvastatin with vitamin D, oxidative stress, and neurotransmitter-related outcomes in rats

    Articolo :118582

    Sally A. Fahim, Muhammad Y. Al-Shorbagy, Rabab H. Sayed, Albeir Messiha, Muhammed A. Saad

    Riassunto Riassunto Mappa Mappa   
  • ·Tumor-targeted delivery of CXCL10 by mesenchymal stromal cells potentiates adoptive T cell therapy to treat solid tumors

    Articolo :118579

    Jeong Ho Yoon, Gyu-Bum Yeon, Hojae Lee, Hyunseo An, Jiwon Oh, Seok-Jin Kang, In-Byung Park, Seon Ah Lim, Soo Seok Hwang, Dae-Sung Kim, Ji Hyung Kim, Taehoon Chun, Yang-Xin Fu, Joonbeom Bae

    Riassunto Riassunto Mappa Mappa   
  • ·Amphiregulin reflects brain metastasis progression and leads to PD-L1 expression in non-small cell lung cancer cells

    Articolo :118600

    Dimitri Leite Ferreira, Tiphaine Biojout, Céline Bazille, Maelle Guyot, Lucie Malandain, Laureline Charrier, Jérôme Toutain, Elodie Peres, Samuel Valable, Jeannick Madelaine, Jérôme Levallet, Guénaëlle Levallet, Emmanuel Bergot

    Riassunto Riassunto Mappa Mappa   
  • ·Anti-inflammatory and inflammasome-modulating effects of Jinmu-Tang, a Korean traditional medicine: Integrated network pharmacology and experimental evaluation in a DSS-induced colitis model

    Articolo :118587

    Jin Ah Ryuk, Seong Eun Jin, Ami Lee, Seol Jang, Hyunil Ha, Youn-Hwan Hwang

    Riassunto Riassunto Mappa Mappa   
  • ·Safety and efficacy of immune cell therapeutics targeting α-PD-L1 in lung cancer

    Articolo :118594

    A-Ram Lee, Hee Young Kang, Yu Bin Lee, Soo Yun Lee, Min-Heui Yoo, Seok-Min Kim, Wan-Jung Im, Ji-Young Kim, Kyoung-Sik Moon, Tae-Don Kim, Sang-Jin Park

    Riassunto Riassunto Mappa Mappa   
  • ·Normobaric oxygen treatment in a depression-like model in male and female rats – Safety, behavioral benefits, and modulation of serotonin and inflammatory markers

    Articolo :118599

    Sarit Uzzan, Ira-Sivan Rostevanov, Ofer Prager, Haiat Nujedat, Jacob Kaplanski, Paul Picton, Alon Friedman, Abed N. Azab

    Riassunto Riassunto Mappa Mappa   
  • ·Comparative evaluation of bispecific antibody formats targeting PD-1 and LAG-3 for dual checkpoint blockade in cancer immunotherapy

    Articolo :118583

    Jie Wang, Ning Shi, Pinnan Zhao, Yangyihua Zhou, Juan Tian, Yaowei Ma, Xuechen Yang, Jiannan Feng, Chunxia Qiao, Xinying Li, Yan Zhang, Xiang Gao, Longlong Luo

    Riassunto Riassunto Mappa Mappa  
  • ·Mitigation of biochemical stress response effects in Swiss albino mice via Syzygium cumini and Nigella sativa seed extract dietary supplementation following deltamethrin exposure

    Articolo :118585

    Anupam Kumar, Joydeep Dutta, Anand Mohan, Neeta Raj Sharma, Gaurav Kumar, Arun Karnwal, Tabarak Malik

    Riassunto Riassunto Mappa Mappa   
  • ·Visnagin mitigates acute kidney injury caused by lipopolysaccharide administration by inhibiting the NF-κB and pyroptosis pathways

    Articolo :118578

    Sheng-Wen Wu, Chien-Ying Lee, Shiuan-Shinn Lee, Wen-Ying Chen, Chun-Jung Chen, Ching-Chi Tseng, Chen-Yu Chiang, Yu-Hsiang Kuan

    Riassunto Riassunto Mappa Mappa  
  • ·Bridging predictions with experimental reality: In vitro evaluation of phenolic natural products as SARS-CoV-2 exoribonuclease inhibitors

    Articolo :118588

    Matěj Danda, Barbora Chvátalová, Daniela Nečasová, Ivana Křížová, Tomáš Ruml, Michaela Rumlová

    Riassunto Riassunto Mappa Mappa   
  • ·Precision targeting of CXCR4⁺ leukemia cells by a humanized MMAE-nanoconjugate in an AML mouse model

    Articolo :118573

    Annabel Garcia-León, Julián I. Mendoza, Ariana Rueda, Lorena Alba-Castellon, Josep F. Nomdedéu, Alberto Gallardo, Jorge Sierra, Ana Garrido, Esther Vázquez, Antonio Villaverde, Ramon Mangues, Ugutz Unzueta, Isolda Casanova

    Riassunto Riassunto Mappa Mappa   
  • ·Neuroinflammatory suppression with protocatechuic acid attenuates Alzheimer’s disease phenotypes in 5 ×FAD transgenic mice

    Articolo :118598

    Yoonsu Kim, Minjung Cho, Chang-Jin Jeon, Gyuhyeong Goh, Myungjin Kim

    Riassunto Riassunto Mappa Mappa   
  • ·Combined haptoglobin and hemopexin therapy for the treatment of cardiopulmonary dysfunction in sickle cell disease

    Articolo :118595

    Melissa J. Lucero, Christina Lisk, Delaney Swindle, Francesca Cendali, Saini Setua, Kiruphagaran Thangaraju, Alamzeb Khan, David I. Pak, Quintin O’Boyle, Shuwei Lu, Robert Tolson, Seth Zaeske, Saqib Khan, Nishant Rana, Natalie Westover, Pavel Davizon-Castillio, Gemlyn George, Kathryn Hassell, Rachelle Nuss, Nathan Brinkman, Thomas Gentinetta, Christy Niemeyer, Pedro Cabrales, Andre Palmer, Angelo D’Alessandro, Paul W. Buehler, David C. Irwin

    Riassunto Riassunto Mappa Mappa   
  • ·Unlocking withaferin-A: Structural design toward next-generation antikinetoplastid agents

    Articolo :118591

    Eduardo Hernández-Álvarez, Carlos J. Bethencourt-Estrella, Meriam Ben Youssef, Atteneri López-Arencibia, Jacob Lorenzo-Morales, Isabel L. Bazzocchi, José E. Piñero, Ignacio A. Jiménez

    Riassunto Riassunto Mappa Mappa   
  • ·A millifluidic esophagus on-a-chip model for evaluating a natural remedy-mediated mucosal repair in GERD

    Articolo :118609

    Maria Elisabetta Federica Palamà, Ketty Gianesin, Elisa Caracciolo, Maurizio Aiello, Silvia Scaglione, Paolo Lucchese, Vincenzo Savarino

    Riassunto Riassunto Mappa Mappa  
  • ·N-Methyl-N-((1-methyl-5-(3-(piperidin-1-yl)propoxy)-1H-benzo[d]imidazol-2-yl)methyl)prop-2-yn-1-amine (MBA-159), a new multitarget small molecule for the therapy of Alzheimer’s disease

    Articolo :118603

    Óscar M. Bautista-Aguilera, Aleksandra Manik, Daniel Diez-Iriepa, Natalia Szałaj, Paula Zaręba, Anna Więckowska, Paweł Żmudzki, Ewelina Honkisz-Orzechowska, Damijan Knez, Stanislav Gobec, Kinga Sałat, Borja Martínez-Alonso, Víctor Guarnizo-Herrero, Guillermo Torrado Durán, Carlos Torrado-Salmerón, Aina Bellver-Sanchis, Inaya Nsiona-Defise, Marta Ribalta-Vilella, Mercè Pallàs, Francisco López-Muñoz, Christian Griñán-Ferré, José Marco-Contelles, Isabel Iriepa

    Riassunto Riassunto Mappa Mappa   
  • ·Plumbagin improves pulmonary vascular remodeling in PAH via miR-21-5p/MMP/TIMP regulation, with diagnostic implications for cardiac function

    Articolo :118604

    Chong-Chao Hsieh, Hsuan-Fu Kuo, Hsiao-Hsuan Wang, Mo Da-Sang Hua, I-Ling Chen, Jia-Ling Lin, Yi-Ching Lo, Zi-Jing Lin, Yung-Hsiang Chen, Yur-Ren Kuo, Chih-Hsin Hsu, Po-Len Liu

    Riassunto Riassunto Mappa Mappa   
  • ·Developing a functional non-animal CNS stress model utilizing long-term potentiation with human iPSC-cortical neurons to evaluate therapeutics

    Articolo :118556

    Kaveena Autar, Xiufang Guo, Haley Powell, Aakash Patel, Mridu Malik, Marcella Grillo, Nesar Akanda, Narasimhan S. Narasimhan, Will Bogen, Christopher Long, Ramy M. Ammar, James Hickman

    Riassunto Riassunto Mappa Mappa   
  • ·Therapeutic role of resveratrol treatment on inflammation and oxidative stress-mediated renal and cardiac dysfunction in isoproterenol (ISO) administered ovariectomized female Long Evans rats

    Articolo :118571

    Tahmina Yasmin, Mirza Alimullah, Md Junaeid Rahman, Shamima Sultana, Shanaz Siddiqua, Ishrat Jahan, Sohel Rana, Nusrat Subhan, Ferdous Khan, Md Ashraful Alam, Nasrin Akhter

    Riassunto Riassunto Mappa Mappa   
  • ·First lepidiline-inspired 1,3-dibenzyl 2-CF₃S-imidazoliums: Design, synthesis and cytotoxic activity study

    Articolo :118606

    Wiktor K. Poper, Marta Denel-Bobrowska, Agnieszka B. Olejniczak, Marcin Jasiński

    Riassunto Riassunto Mappa Mappa   
  • ·Inhibition of acid sphingomyelinase increases SMN levels and connects sphingolipid metabolism to Spinal Muscular Atrophy

    Articolo :118610

    Ana M. Brokate-Llanos, María Beltran, Andrés Garzón, Ana Garcera, María P. Miralles, Ferrán Celma-Nos, Alejandro Campoy-López, Rosa M. Soler, Manuel J. Muñoz, Antonio J. Pérez-Pulido

    Riassunto Riassunto Mappa Mappa   
  • ·Interferon signature predicts chemotherapy resistance in acute myeloid leukaemia

    Articolo :118612

    Ela Cerovska, David Kundrat, Zdenek Krejcik, Cyril Salek, Jan Musil, Eliska Cechova, Michaela Dostalova Merkerova, Monika Belickova, Hana Remesova

    Riassunto Riassunto Mappa Mappa   
  • ·Autophagy inhibition enhances sensitivity of alpelisib in PI3K–mutated non-small cell lung cancer

    Articolo :118620

    Jinyoung Kim, Chandani Shrestha, Tae Woo Kim, Sang-Bin Lee, Gwangbin Lee, Dasom Jung, Min Hwang, Shinwon Kang, Hyung Soon Park, Hyunho Kim, Ho Jung An, Dongwoo Chae, Byoung Yong Shim, Jiyoon Kim

    Riassunto Riassunto Mappa Mappa   
  • ·TAS4464, a neddylation inhibitor, mitigates Staphylococcus aureus-induced periprosthetic joint infection by modulating immunosuppressive cell functions

    Articolo :118622

    Kuo-Ti Peng, Jiun-Liang Chen, Yu-Chien Hsieh, Chun-Yuan Hsiao, Chia-Ching Yang, Ju-Fang Liu, Chiang-Wen Lee, Yao-Chang Chiang, Pey-Jium Chang

    Riassunto Riassunto Mappa Mappa   
  • ·Modelling-filtered drug repurposing and first-in-protein SPR validation of histone deacetylase 4 inhibitors for Ataxia-telangiectasia

    Articolo :118621

    Alessia Distefano, Matteo Pappalardo, Roberta Turco, Giuseppe Grasso, Salvatore Guccione

    Riassunto Riassunto Mappa Mappa   
  • ·Feasibility and efficacy of electromotive intraperitoneal drug delivery: A hybrid study

    Articolo :118619

    Nidda Saeed, Hooman Salavati, Jolene Wong Si Min, Sarah Cosyns, Katrien Remaut, Charlotte Debbaut, Mieke Adriaens, Annelies Coene, Wim Ceelen

    Riassunto Riassunto Mappa Mappa  
  • ·Modulation of acetylcholine level by donepezil hydrochloride attenuates the severity of experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis

    Articolo :118630

    Morena Brazil Sant’Anna, Leticia Ferreira Carvalho Corcino, Flavia Souza Ribeiro Lopes, Gessica Sabrina de Assis Silva, Ana Maria Boaventura de Oliveira, Andrea Borrego, Marcelo De Franco, Osvaldo Augusto Sant’Anna, Gisele Picolo

    Riassunto Riassunto Mappa Mappa  
  • ·Therapeutic effect of neural induced-stem cell-derived exosomes by regulating ERK/p38/NF-κB in traumatic brain injury

    Articolo :118616

    Dohee Kim, Jinsu Hwang, Eunjae Jang, Hyong-Ho Cho, Byeong C. Kim, Han-Seong Jeong, Sujeong Jang

    Riassunto Riassunto Mappa Mappa   
  • ·Structural characterization of Factor H via computational methods: Implications for disease and therapy

    Articolo :118628

    Atala Bihari Jena, Asim K. Duttaroy

    Riassunto Riassunto Mappa Mappa   
  • ·Membrane-coated BLM gene silencing plasmids and doxorubicin nanoparticles targeted for synergistic inhibition of triple-negative breast cancer

    Articolo :118566

    Haifeng Ai, Yixin Liu, Xuelian Luo, Wangming Zhang, Xiaohua Liu, Song Xiao, Bixiang Jin, Jielin Liu

    Riassunto Riassunto Mappa Mappa   
  • ·Sphingolipid metabolism and insulin resistance – Does cannabigerol protect against experimental colitis induced by high-fat high-sucrose diet?

    Articolo :118623

    Daniel Michalak, Klaudia Sztolsztener, Karolina Konstantynowicz-Nowicka, Ewa Harasim-Symbor, Irena Kasacka, Brintha Croos, Adrian Chabowski

    Riassunto Riassunto Mappa Mappa  
  • ·Comparative in vitro evaluation of elastogenic compounds for pharmacological modulation of extracellular matrix production in human dermal fibroblasts

    Articolo :118641

    Roman Krymchenko, Nancy Avila-Martinez, Bouke K.H.L. Boekema, Toin H. van Kuppevelt, Willeke F. Daamen

    Riassunto Riassunto Mappa Mappa   
  • ·TRPA1 inhibition reduces ocular pain and corneal neurogenic inflammation in a mouse model of dry eye disease

    Articolo :118625

    Tiffany Migeon, Arnaud Cordovilla, Anaïs Potey, Cécile Delarasse, Tristan Hourcade, Elodie Reboussin, Céline Olmière, Christophe Baudouin, Annabelle Réaux-Le Goazigo, Stéphane Mélik Parsadaniantz

    Riassunto Riassunto Mappa Mappa   
  • ·Gene and drug-mediated SERCA2a activation restores cardiac function and metabolic balance in diabetic mice

    Articolo :118617

    Soojeong Kang, Abdul Majid, Nadjib Hammoudi, Djamel Lebeche

    Riassunto Riassunto Mappa Mappa   
  • ·Baicalin counteracts valproic acid-induced memory impairment by restoring neurogenesis in the hippocampus of adult rats

    Articolo :118618

    Supunsa Yanpaisan, Puncharatsm Pannin, Jariya Umka Welbat, Apiwat Sirichoat, Nataya Sritawan, Peter Wigmore, Anusara Aranarochana

    Riassunto Riassunto Mappa Mappa  
  • ·Structure-based discovery of a novel nuclear receptor PPARγ inhibitor: Implications for obesity and metabolic disease intervention

    Articolo :118615

    Phum Tachachartvanich, Rapeepat Sangsuwan, Nonticha Ngernpisutsilp, Hunsa Prawat, Wirongrong Kaweetripob, Mathuros Ruchirawat, Somsak Ruchirawat

    Riassunto Riassunto Mappa Mappa   
  • ·Multi-omics profiling reveals ortho-topolin riboside and protocatechualdehyde combination exhibits anti-proliferative activity by modulating metabolic pathways in in vitro and in vivo radio-resistant MDA-MB-231 cell models

    Articolo :118631

    Seung Min Nam, Dae Kyeong Kim, Ji Soo Kim, Seungcheol Lee, Junyoung Ahn, Somi Kim Cho, Hyung-Kyoon Choi

    Riassunto Riassunto Mappa Mappa   
  • ·Boosting curcumin derivatives' cytotoxicity in cancer cells with light: An in vitro study

    Articolo :118643

    Giulia Greco, Eleonora Turrini, Fabio Ferrini, Francesca Maffei, Giulia Neggiani, Matteo Calvaresi, Manuele Di Sante, Matteo Di Giosia, Federica Belluti, Piero Sestili, Carmela Fimognari

    Riassunto Riassunto Mappa Mappa  
  • ·Myeloid ADAM17 induces ST2⁺ T regulatory cells that limit obesity-induced metabolic inflammation through changes in both membrane and soluble TNF

    Articolo :118627

    Joseph C. Lownik, Matthew P. Zellner, Jared Farrar, Anuj Tharakan, Francesco S. Celi, Daniel H. Conrad, Rebecca K. Martin

    Riassunto Riassunto Mappa Mappa   
  • ·The three dicaffeoylquinic acids of Erigeron breviscapus strengthen anticoagulation of warfarin in rats: Implications in pharmacokinetics and pharmacodynamics

    Articolo :118640

    Yue Zhao, Mengnan Qin, Lin Wei, Xuepeng Shi, Shiwei Xu, Bing Shao, Chunjuan Yang, Gaofeng Liu

    Riassunto Riassunto Mappa Mappa   
  • ·Immune modulatory and vascular protective effects of Ibudilast in post-stroke inflammation

    Articolo :118638

    Sima Abbasi-Habashi, Yonglie Ma, Glen C. Jickling, Ian R. Winship

    Riassunto Riassunto Mappa Mappa   
  • ·Effects of JNJ-46356479 and clozapine on VGLUT1 and GAD65/67 brain levels and expression of genes related to glutamate and GABA in mice postnatally exposed to ketamine

    Articolo :118639

    Albert Martínez-Pinteño, David Olivares-Berjaga, Natalia Rodríguez, Juan-Ignacio Mena, Lucia Prohens, Sergi Mas, Constanza Morén, Eduard Parellada, Patricia Gassó

    Riassunto Riassunto Mappa Mappa   
  • ·Targeting acute myeloid leukemia resistance with two novel combinations demonstrate superior efficacy in TP53, HLA-B, MUC4 and FLT3 mutations

    Articolo :118647

    Elham Gholizadeh, Ehsan Zangene, Alun Parsons, Mika Kontro, Caroline A. Heckman, Mohieddin Jafari

    Riassunto Riassunto Mappa Mappa   
  • ·Cardiac regeneration revisited: Enhanced cardiomyocyte differentiation and repair through composite microenvironments and small molecules

    Articolo :118642

    Manizheh Azhdari, Shahram Rabbani, Nader Tanideh, Safieh Boroumand

    Riassunto Riassunto Mappa Mappa  
  • ·Amifostine and melatonin attenuate radiation-induced oxidative stress, inflammation, and fibrotic remodeling in the vocal folds and subglottic glands of rats

    Articolo :118658

    Ji Min Kim, Gi Cheol Park, Hyoun-Wook Lee, Soo-Young Bang, Dong-Hyun Kim, Won-Taek Kim, Sung-Chan Shin, Yong-il Cheon, Byung-Joo Lee

    Riassunto Riassunto Mappa Mappa  
  • ·Jaceosidin, a natural polymethoxyflavone, suppresses leukemia cell growth and impairs lipid metabolism-dependent survival in AML and cytarabine-resistant cells

    Articolo :118654

    Trung Q. Phan, Je-Wen Liou, Liang-In Lin, Wei-Han Huang, Ming-Jiuan Wu, Pei-Yi Chen, Jui-Hung Yen

    Riassunto Riassunto Mappa Mappa   
  • ·A Trojan horse: Chemical boosting of Plasmodium falciparum whole sporozoite vaccine immunogenicity

    Articolo :118666

    Chanel Milène Naar, Roos van Schuijlenburg, Maarten van Meerbeek, Luís Almeida, Fijs W.B. van Leeuwen, Meta Roestenberg

    Riassunto Riassunto Mappa Mappa   
  • ·Phenolic zingerone nanoparticles impede cell cycle progression to compete against human urothelial carcinoma

    Articolo :118675

    Mei-Lang Kung, Tian-Huei Chu, Shuchen Hsieh, Ching-Chia Li, Wei-Ming Li, Bi-Wen Yeh, Wen-Jeng Wu

    Riassunto Riassunto Mappa Mappa   
  • ·FGF/FGFR inhibitors downmodulates c-Myc oncoprotein and hampers the growth of adrenocortical carcinoma

    Articolo :118677

    Sara Taranto, Jessica Faletti, Mariangela Tamburello, Roberto Ronca, Giulia Garattini, Giorgia Gazzaroli, Marta Turati, Edoardo Rocca, Riccardo Castelli, Andrea Abate, Luca Mignani, Marta Laganà, Constanze Hantel, Sandra Sigala, Marco Presta, Arianna Giacomini

    Riassunto Riassunto Mappa Mappa   
  • ·Integrated pharmacokinetic properties and tissue distribution of Corydalis saxicola Bunting total alkaloids in HFHCD-induced mice: Implications for pharmacokinetic variability in MASH treatment

    Articolo :118665

    Qiushuang Sun, Huan Chen, Qianqian Lin, Yanyi Wu, Yuanyuan Lei, Xianhai Luo, Ning Li, Luzhou Xu, Sufeng Zhou, Jun Cheng, Fang Huang, Zhixia Qiu

    Riassunto Riassunto Mappa Mappa   
  • ·Sex and age-related differences in humoral and cellular responses to the recombinant zoster vaccine in people living with HIV

    Articolo :118663

    Cristina Díez, Carlos Pita-Martínez, Marta Quero-Delgado, Aurora Gómez-Tórtola, Chiara Fanciulli, Ana Marchan, Teresa Aldámiz-Echevarría, Daniel Sepúlveda-Crespo, Francisco Tejerina, Leire Pérez-Latorre, Isabel Gutiérrez, Juan Carlos López, Isidoro Martínez, Salvador Resino

    Riassunto Riassunto Mappa Mappa   
  • ·The role of H₂S in isoproterenol-induced cardiac hypertrophy: A comparative study using slow releaser GYY4137 and a newly synthetized fast releaser BM-112

    Articolo :118660

    Alexandra Gyöngyösi, Simon Eskeif, Richard Kajtár, Ferenc Fenyvesi, Adina Fésüs, Pál Herczegh, Anikó Borbás, Ilona Bereczki, István Lekli

    Riassunto Riassunto Mappa Mappa   
  • ·MCH11, a new monoacylglycerol lipase inhibitor, reduces ethanol consumption and motivation to drink in mice, with sex-dependent differences

    Articolo :118662

    Abraham B. Torregrosa, María S. García-Gutiérrez, Daniela Navarro, Francisco Navarrete, Jorge Manzanares

    Riassunto Riassunto Mappa Mappa   
  • ·Aloe-derived polysaccharides (APS) mitigate SARS-CoV-2 Omicron BQ1.1 infection by preserving epithelial integrity and reducing viral load in human airway epithelial (HAE) cultures

    Articolo :118657

    Wilfried Posch, Ekambaranellore Prakash, Sophie Ann Erckert, Viktoria Zaderer, Rosa Bellmann-Weiler, Uvarani Chokkalingam, Singh Anuma, Stefan Pöhlmann, Markus Hoffmann, Doris Wilflingseder

    Riassunto Riassunto Mappa Mappa   
  • ·Pioglitazone mitigates high-fat diet-induced cardiac lipotoxicity and vulnerable arrhythmias by reducing excess lipid intermediates

    Articolo :118672

    Yung-Hsin Yeh, Mei-Ling Cheng, Cheng-Hung Yang, Wei-Jan Chen, Yi-Hsin Chan

    Riassunto Riassunto Mappa Mappa   
  • ·Structure-activity relationships of contulakin-G: Design, synthesis, and characterization of Thr¹⁰ analogs for pain modulation

    Articolo :118664

    Annik Lanoie, Sára Ferková, Édouard Caron-Duval, Juliana C.C. Dallagnol, Sitan Diarra, Alexandre Murza, Alexandre Tremblay, Léa Théroux, Émile Breault, Amirmohammad Ranjbaran, Léa Landry, Jérôme Côté, Jean-Michel Longpré, Pierre-Luc Boudreault, David Chatenet, Philippe Sarret

    Riassunto Riassunto Mappa Mappa   
  • ·Phosphatidylcholine-bound palmitoleic acid: A bioactive key to unlocking macrophage anti-inflammatory functions

    Articolo :118652

    Miguel A. Bermúdez, Clara Meana, Alvaro Garrido, Alfonso Pérez-Encabo, María A. Balboa, Jesús Balsinde

    Riassunto Riassunto Mappa Mappa   
  • ·Sodium glucose co-transporter 2 inhibitor empagliflozin prevents endothelial dysfunction induced by oscillatory shear stress

    Articolo :118670

    Xiaoling Li, Mengnan Wang, Jil Seehaber, Charlotte Stuhldreier, Yumna A. Butt, Marta Z. Pacia, Markus W. Hollmann, Benedikt Preckel, Martin Albrecht, Coert J. Zuurbier, Nina C. Weber

    Riassunto Riassunto Mappa Mappa   
  • ·Pleiotrophin and receptor protein tyrosine phosphatase β/ζ as key modulators of high-fat diet-induced cognitive impairment and brain alterations

    Articolo :118671

    Héctor Cañeque-Rufo, Teresa Fontán-Baselga, Elisa Rivera-Illades, Marta Vicente-Rodríguez, Esther Gramage, José María Zapico, Beatriz de Pascual-Teresa, María del Pilar Ramos-Álvarez, Gonzalo Herradón

    Riassunto Riassunto Mappa Mappa   
  • ·Unravelling the role of cerebellar α6GABA_A receptors in anti-tremor pharmacotherapies

    Articolo :118644

    Ya-Hsien Huang, Han-Yun Hsueh, Ming Tatt Lee, Chen-Jiun Yeh, Lih-Chu Chiou

    Riassunto Riassunto Mappa Mappa  
  • ·Balancing rigidity and flexibility: Optimised 4-(hexyloxy)benzoate antagonists with enhanced affinity and tuneable duration at muscarinic receptors

    Articolo :118653

    Eva Dolejší, Eva Mezeiova, Jana Bláhová, Nikolai Chetverikov, Alena Janoušková-Randáková, Dominik Nelic, Lukas Prchal, Barbora Svobodova, John Boulos, Jan Korabecny, Jan Jakubík

    Riassunto Riassunto Mappa Mappa   
  • ·Transcriptomic profiling of organoids derived from malignant effusions uncovers lncRNA MEG3 and target genes potentially involved in platinum resistance in serous ovarian carcinoma

    Articolo :118668

    Naiade Calanca, Claudia Aparecida Rainho, Debora Kazumi Maeda, Luiza Côrtes, Rolando André Rios Villacis, Daniela Bizinelli, Hellen Kuasne, Mads Malik Aagaard, Lars Ulrik Fokdal, Karina Dahl Steffensen, Lars Henrik Jensen, Silvia Regina Rogatto

    Riassunto Riassunto Mappa Mappa   
  • ·Protective effects of 2,3,5,4’-tetrahydroxystilbene-2-O-β-D-glucoside against cadmium toxicity involve BDNF/TrkB and PI3K/Akt signaling pathways

    Articolo :118602

    Run-Ze Gu, Abduwares Tursun, Si-Jia Zhong, Jin-Bo Cheng, Xiao-Yan Qin, Chang Cao

    Riassunto Riassunto Mappa Mappa   
  • ·Therapeutic efficacy of sacituzumab govitecan in recurrent refractory germ cell tumors

    Articolo :118659

    Natália Udvorková, Viktória Blahová, Pavlína Malchárková, Silvia Jochová, Katarína Kaľavská, Adriana Fekiačová, Jaroslav Pavel, Samuel Horák, Andrej Džongov, Jakub Janko, Michal Pastorek, Michal Chovanec, Zuzana Čierna, Michal Mego, Lucia Kučerová

    Riassunto Riassunto Mappa Mappa   
  • ·GPR40 agonist ameliorates neurodegeneration by regulating mitochondria dysfunction and NLRP3 inflammasome in Alzheimer’s disease animal models

    Articolo :118678

    Tae-Young Ha, Yeji Kim, Seung Min Lim, Yongjae Hong, Keun-A Chang

    Riassunto Riassunto Mappa Mappa   
  • ·Modeling of glucocorticoid resistance in multiple myeloma reveals mechanisms and markers of glucocorticoid resistance

    Articolo :118656

    Bert Luyckx, Mélanie Derollez, Eleni Staessens, Annick Verhee, Daria Fijalkowska, Pieter Van Vlierberghe, Steven Goossens, Dorien Clarisse, Karolien De Bosscher

    Riassunto Riassunto Mappa Mappa   
  • ·Prenatal paroxetine dysregulates monoamine homeostasis and affects placental hemodynamics in the rat fetoplacental unit

    Articolo :118680

    Hana Horackova, Ivana Musilova-Kacerovska, Cilia Abad, Rona Karahoda, Veronika Vachalova, Ramon Portillo, Mireia Viñas-Noguera, Kasin Yadunandam, Daniel Heblik, Eva Cifkova, Miroslav Lisa, Martin Sterba, Jaroslav Stranik, Alexandre Bonnin, Frantisek Staud

    Riassunto Riassunto Mappa Mappa   
  • ·Design and synthesis of pyrazolopyrimidinone derivatives as dual VEGFR/Aurora kinase inhibitors against hepatocellular and breast carcinomas

    Articolo :118679

    Kurls E. Anwer, Botros Y. Beshay, Marium M. Shamaa, Nour E.A. Abd El-Sattar, Amira Senbel

    Riassunto Riassunto Mappa Mappa   
  • ·Serdemetan promotes bone regeneration via coordinated regulation of osteoblast and osteoclast activity

    Articolo :118686

    Sol Jeong, Seung-Chan An, Hyun-Ju An, Sungjoon Lim, Jin Man Kim, Soonchul Lee

    Riassunto Riassunto Mappa Mappa   
  • ·Nicorandil protects against cardiac I/R injury via Mt2-mediated mitochondrial homeostasis

    Articolo :118687

    Zi-Zhuo Li, Yan-Liang An, Wei-Jia Yu, Xiao-Peng Dong, Ding-Yu Shi, Hui-Yang Wang, Shu-Jing Liu, Zhi-Chao Dong, Qiu-Yue Lin, Bo Zhang

    Riassunto Riassunto Mappa Mappa   
  • ·SMARCA1 regulates PARP1-dependent ABC transporters expression and mediates doxorubicin resistance in triple-negative breast cancer

    Articolo :118698

    Karolina Gronkowska, Kinga Kołacz-Milewska, Sebastian Skoczylas, Éva Nagy, Damian Jacenik, Lóránt Székvölgyi, Agnieszka Robaszkiewicz, Magdalena Strachowska

    Riassunto Riassunto Mappa Mappa   
  • ·GB10, a novel antibody fusion protein targeting VEGF/Ang-2, exhibits promising therapeutic efficacy for neovascular eye diseases

    Articolo :118690

    Xiling Wei, Yuxin Qiu, Wei Shang, Xiangling Zhang, Wenjie Yang, Xi Chen, Huiming Li, Suofu Qin

    Riassunto Riassunto Mappa Mappa   
  • ·An intraocular lens coated with polycaprolactone and methotrexate as a slow-release system for prophylaxis of posterior capsule opacification in-vitro

    Articolo :118693

    Christina Hilterhaus, Arne J. Speidel, Simone C. Felis, Anna Hillenmayer, Armin Wolf, Christian M. Wertheimer

    Riassunto Riassunto Mappa Mappa   
  • ·Chemerin-CMKLR1 differentially mediated OGD/R-induced mitochondrial dysfunction, oxidative stress, and autophagy in microglia and neurons

    Articolo :118702

    Pei-Yan Long, Zhi Tang, Na Cai, Zhi-Qin Yan, Xiao Gao, Zheng-Wei Wang, Zhi-Zhong Guan, Xiao-Lan Qi, Ruiqing Ni, Yan Xiao

    Riassunto Riassunto Mappa Mappa   
  • ·Inhibition of AKT or mTOR molecules mitigates obesity-associated metabolic disorders in Riz1^-/- mice with obesity

    Articolo :118707

    Xiaolei Xie, Jiahui Yan, Jinghong Zhang, Huiru Ye, Jiaxing Li, Weiguo Yin

    Riassunto Riassunto Mappa Mappa   
  • ·Tannic acid suppresses vitamin C’s hormetic effects in HCT-15 low-SVCT2-expressing colorectal cancer cells by upregulating SVCT2

    Articolo :118701

    Kantawong Kawalin, Hakim Meutia Diva, Phuong T. Ho, Mi-Gi Lee, Hee Kang, Taek-Kyun Lee, Sukchan Lee

    Riassunto Riassunto Mappa Mappa   
  • ·Cannabidivarin directly targets the immunosuppressive activity of regulatory myeloid cells in tumors

    Articolo :118697

    Miryam Steinberg, Iris Wyrobnik, Shiri Procaccia, Ronen Rosenblum, Anat Gelfand, Shaked Avisidris, Hila Novak-Kotzer, David Meiri

    Riassunto Riassunto Mappa Mappa   
  • ·Targeting serine metabolism vulnerability in omipalisib-resistant acute myeloid leukemia with phosphoglycerate dehydrogenase inhibitors

    Articolo :118689

    Chi-Yang Tseng, Yu-Hsuan Fu, Da-Liang Ou, Hsin-An Hou, Hsiung-Fei Chien, Liang-In Lin

    Riassunto Riassunto Mappa Mappa   
  • ·Myotube-specific vulnerability to clozapine

    Articolo :118661

    Gloria Buffi, Mara Fiorani, Andrea Guidarelli, Nazanin Bagherlou, Andrea Spina, Lorenzo Scocchia, Giorgia Maria Renna, Ester Zito, Orazio Cantoni

    Riassunto Riassunto Mappa Mappa   
  • ·EPICYCLE: A confirmatory preclinical study of the anti-rhabdomyosarcoma efficacy of BET bromodomain and cyclin-dependent kinase 9 inhibitors

    Articolo :118704

    Bernhard Haller, Günther H.S. Richter, Marco Wachtel, Lena Schuler, Carla Regina, Bernhard Renz, Marvin Jens, Ingrid Bechtold, Yekaterina Gadasheva, Ebrahem Hamed, Samanta Kisele, Mathilda Knoblauch, Maximilian RA Koch, Dmitry Lupar, Satoshi Nakano, Katharina Pardon, Paul J. Pärschke, Claudia Winter, Ulf Tölch, Beat W. Schäfer, Ana Banito, Irene von Lüttichau, Simone Hettmer

    Riassunto Riassunto Mappa Mappa   
  • ·Modified Zn-MOF multifunctional nanoparticles for combination therapy of DN and exploratory study of the nephroprotective effect

    Articolo :118713

    Yuna Tong, Xiuxiu Li, Yuxuan Zhu, Xiaohui Liao, Ling Zhang

    Riassunto Riassunto Mappa Mappa   
  • ·Non-clinical GLP genotoxicity and rodent oral toxicity studies of 6′-hydroxy justicidin B for anti-COVID-19 agent development

    Articolo :118708

    Min Heui Yoo, Seng-Min Back, Min Seong Jang, Junguk Choi, Jihyun Jeon, Kyong-Cheol Ko, Yong-Bum Kim

    Riassunto Riassunto Mappa Mappa   
  • ·Manganese porphyrin [MnTE-2-PyP]⁵⁺ improves maternal and offspring glycemic homeostasis, placental morphology, and redox balance in diabetic pregnant rats

    Articolo :118694

    Adriana Lopes da Silva, Bianca Reis Santos, Luciano Cardoso Santos, Jeane Martinha dos Anjos Cordeiro, Erikles Macêdo Barbosa, Brenda Geovana Campos Martins, Cibele Luz Oliveira, Emilly Oliveira Santos, Natália Panhoca Rodrigues, Rodrigo Oliveira Malheiros, Júlio Santos Rebouças, Gilson DeFreitas-Silva, Daniel de Assis Santos, Stephanie Carvalho Borges, Mário Sérgio Lima de Lavor, Estela Bevilacqua, Juneo Freitas Silva

    Riassunto Riassunto Mappa Mappa   
  • ·Co-treatment of ticagrelor and anti-PD-1 immunotherapy in tumor-associated macrophages reduces pancreatic cancer cell growth and migration through the TGF-β1/Smad2 pathway

    Articolo :118695

    Ying Kang, Emmanuel Boadi Amoafo, Philomena Entsie, Buddhadev Layek, Paul M. Grandgenett, Michael A. Hollingsworth, Marina Pasca di Magliano, Elisabetta Liverani

    Riassunto Riassunto Mappa Mappa   
  • ·Cetuximab-mediated antibody-dependent cell-mediated cytotoxicity enhances anti-tumor efficacy of patient-derived natural killer cells in pancreatic cancer

    Articolo :118714

    EunJi Kim, Eunsung Jun, You-Sun Kim, HAEYEOP KIM, Hajeong An, Seong-Jin Kim, Bokyung Min, Song Cheol Kim

    Riassunto Riassunto Mappa Mappa   
  • ·Pentasaccharide anticoagulant fondaparinux inhibits diphtheria toxin

    Articolo :118705

    Sebastian Heber, Laura Zeller, Amelie Resch, Joscha Borho, Sophia Kistermann, Stephan Fischer, Panagiotis Papatheodorou, Holger Barth

    Riassunto Riassunto Mappa Mappa   
  • ·The multifaceted mechanism of action of quinoline thiosemicarbazone based on disruption of iron homeostasis and selective IGF1R inhibition leading to oxidative stress induction

    Articolo :118692

    Patryk Zioła, Katarzyna Malarz, Patrycja Rawicka, Mateusz Korzec, Maciej Serda, Anna Boguszewska-Czubara, Marcin Pacholczyk, Maria Książek, Anna Mrozek-Wilczkiewicz

    Riassunto Riassunto Mappa Mappa   

• Short Communications

  • ·Multimodal immune profiling of peripheral blood to predict the response to intra-articular autologous blood-derived orthobiologic treatment in patients with knee osteoarthritis

    Articolo :118674

    Antonio Tonutti, Valentina Granata, Veronica Marrella, Chiara Camisaschi, Simone Puccio, Emanuela Morenghi, Rita Ragusa, Cristiano Sconza, Nicola Rani, Giuseppe Filardo, Berardo Di Matteo, Carlo Selmi, Cristina Sobacchi, Angela Ceribelli

    Riassunto Riassunto Mappa Mappa   

• Letters to the Editor

  • ·Letter to the Editor regarding “Integrative systems biology, transcriptomic profiling, and experimental validation reveal enterolactone as a multi-target inhibitor of metastatic signalling in triple-negative breast cancer”

    Articolo :118605

    Parth Aphale, Shashank Dokania, Himanshu Shekhar

    Riassunto Riassunto Mappa Mappa
  • ·FXR agonism in MASLD: A complex II bottleneck

    Articolo :118699

    Boyan Liu, Anyun Ding

    Mappa Mappa

• Corrigendum

  • ·Corrigendum to “The synergy between miR-486–5p and tamoxifen causes profound cell death of tamoxifen-resistant breast cancer cells” [Biomedicine & Pharmacotherapy141 (2021) 111925]

    Articolo :118474

    Behzad Mansoori, Souzan Najafi, Ali Mohammadi, Haleh AsadollahSeraj, Pouria Savadi, Behnaz Mansoori, Afsaneh Nazari, Ahad Mokhtarzadeh, Elmira Roshani, Pascal HG Duijf, William Cho, Behzad Baradaran

    Mappa Mappa  
  • ·Corrigendum to “Long non-coding RNA NEAT1 promotes bladder progression through regulating miR-410 mediated HMGB1” [Biomed. Pharmacother. (2020) 121 109248]

    Articolo :118536

    Guang Shan, Tian Tang, Yue Xia, Hui-Jun Qian

     
  • ·Corrigendum to “Regulation of NcRNA-protein binding in diabetic foot” [Biomed. Pharmacother. 160 (2023) 114361]

    Articolo :118555

    Jiayu Zhang, Jing Zhang, Zhou Xu, Deju Zhang, Panpan Xia, Jitao Ling, Xiaoyi Tang, Xiao Liu, Rui Xuan, Meiying Zhang, Jianping Liu, Peng Yu

    
  • ·Corrigendum to “Total flavonoids of rhizoma drynariae ameliorates bone formation and mineralization in BMP-Smad signaling pathway induced large tibial defect rats” [Biomed. Pharmacother., vol. 138 (2021) 111480]

    Articolo :118580

    Weipeng Sun, Minying Li, Yan Zhang, Yingjie Huang, Qunzhang Zhan, Yueyi Ren, Hang Dong, Jiena Chen, Zige Li, Chun Fan, Feng Huang, Zhen Shen, Ziwei Jiang

     
  • ·Corrigendum to “The natural compound andrographolide inhibits human aortic valve interstitial cell calcification via the NF-κB/Akt/ERK pathway” [Biomed. Pharmacother. 125 (2020) 109985]

    Articolo :118613

    Yuming Huang, Xianming Zhou, Ming Liu, Tingwen Zhou, Jiawei Shi, Nianguo Dong, Kang Xu

     
  • ·Corrigendum to “Angiogenesis in the ovary – Proangiogenic factors and their clinical applications” [Biomed. Pharmacother. 191 (2025) 118416]

    Articolo :118614

    Hanna Jankowska-Ziemak, Magdalena Kulus, Kornelia Krajnik, Jakub Kulus, Mikołaj Chwarzyński, Marcin Ciorga, Michał Gnus, Aleksandra Górska, Aleksandra Partyńska, Krzysztof Data, Dominika Domagała, Julia Niebora, Teresa Wysocka, Marek Spaczyński, Dorota Bukowska, Paweł Antosik, Piotr Dzięgiel, Paul Mozdziak, Bartosz Kempisty

    
  • ·Corrigendum to “Exosomes in Alzheimer’s disease: From pathogenesis to therapeutics — A comprehensive review of diagnostic and drug delivery applications” [Biomed. Pharmacother. 192 (2025) 118548]

    Articolo :118632

    Mona Shahlaei, Hamed Afkhami, Amirhossein Ahmadieh-Yazdi, Seyed Hashem Mirmazloumi, Seyedeh Saeideh Sahraei, Mohammad Akbari, Piao Yang, Hamed Manoochehri, Hamid Tanzadehpanah, Hanie Mahaki, Aravind Sundararaman, Sreedivya Mohan, Mohsen Sheykhhasan, Sharafaldin Al-Musawi, Paola Dama

    
  • ·Corrigendum to “A new peptide originated from amphibian skin alleviates the ultraviolet B-induced skin photodamage” [Biomed. Pharma., 150 (2022) 112987]

    Articolo :118646

    Siyu Wang, Meifeng Yang, Saige Yin, Yingxuan Zhang, Yue Zhang, Huiling Sun, Longjun Shu, Yixiang Liu, Zijian Kang, Naixin Liu, Jiayi Li, Ying Wang, Li He, Mingying Luo, Xinwang Yang

     
  • ·Corrigendum to “Assessment of dose-response relationship of 5-fluorouracil to murine intestinal injury” [Biomed. Pharmacother. 106 (2018) 910–916]

    Articolo :118650

    Si Zhang, Yanan Liu, Daochun Xiang, Jinyu Yang, Dong Liu, Xiuhua Ren, Chengliang Zhang

     
  • ·Erratum to “Autophagy inhibition enhances sensitivity of alpelisib in PI3K–mutated non-small cell lung cancer” [Biomed. Pharmacother. 192 (2025), 118620]

    Articolo :118651

    Jinyoung Kim, Chandani Shrestha, Tae Woo Kim, Sang-Bin Lee, Gwangbin Lee, Dasom Jung, Min Hwang, Shinwon Kang, Hyung Soon Park, Hyunho Kim, Ho Jung An, Dongwoo Chae, Byoung Yong Shim, Jiyoon Kim

    

• Retractions

  • ·Retraction notice to “In vivo pathogenesis of colon carcinoma and its suppression by hydrophilic fractions of Clematis flammula via activation of TRAIL death machinery (DRs) expression” [Biomed. Pharmacother. 109 (2019) 2182–2191]

    Articolo :118648

    Fatma Guesmi, Marwa Ben Hmed, Sahdeo Prasad, Amit K. Tyagi, Ahmed Landoulsi

    
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