Sommario

• • ·Scrutinising Lyme disease in the UK

    Pagina :915

     
• • ·Accelerated evolution and spread of multidrug-resistant Plasmodium falciparum takes down the latest first-line antimalarial drug in southeast Asia

    Pagina :916-917

    Didier Ménard, David A Fidock

     
• • ·The unanticipated benefits of protecting young children from malaria

    Pagina :918-919

    Lauren M Cohee, Miriam K Laufer

     
• • ·Devising a strategy for prevention of malaria in pregnant women in the Asia Pacific

    Pagina :919-920

    R Matthew Chico, Jorge Cano

    
• • ·Varicella zoster virus vaccine in patients with haematological malignancies

    Pagina :921-922

    Per Ljungman

    
• • ·Herpes zoster in people who are immunocompromised: what are the options for prevention?

    Pagina :922-924

    Charlotte Warren-Gash, Judith Breuer

    
• • ·First clinical trial of a MERS coronavirus DNA vaccine

    Pagina :924-925

    In-Kyu Yoon, Jerome H Kim

     
• • ·Use of reverse genetics to inform Ebola outbreak responses

    Pagina :925-927

    Robert W Cross, Thomas W Geisbert

    
• • ·Phase 3 trial of treating gonorrhoea with solithromycin

    Pagina :928

    Prabhavathi Fernandes, J Carl Craft

    
• • ·Efficacy of live oral rotavirus vaccines

    Pagina :929

    Bo Zhou, Wenquan Niu

    
• • ·Culture-negative cryptococcal meningitis

    Pagina :929-930

    Kenneth Ssebambulidde, Caleb Skipper, Joshua Rhein

     
• • ·Typhoid Vi-conjugate vaccine for outbreak control in Zimbabwe

    Pagina :930

    Ioana D Olaru, Sekesai Mtapuri-Zinyowera, Nicholas Feasey, Rashida A Ferrand, Katharina Kranzer

    
• • ·Value of observational data for multidrug-resistant tuberculosis

    Pagina :930-931

    Carly A Rodriguez, Carole D Mitnick, Molly F Franke

    
• • ·Bloodstream infections and carbapenem-resistant Enterobacteriaceae in South Korea

    Pagina :931-932

    Eun-Jeong Yoon, Dokyun Kim, Seok Hoon Jeong

    
• • ·Carbapenem-resistant Klebsiella pneumoniae with low chlorhexidine susceptibility

    Pagina :932-933

    Claudia Stein, Szilvia Vincze, Frank Kipp, Oliwia Makarewicz, Sascha Al Dahouk, Mathias W Pletz

     
• • ·Should use of online photographs be exempt from ethical guidelines?

    Pagina :933-934

    Jenell Stewart, Peter DiCampo

    
• • ·Correction to Lancet Infect Dis 2019; 19: 812

    Pagina :e301

    
• • ·15 years of the ECDC

    Pagina :935-936

    Talha Burki

     
• • ·Dolutegravir becomes first choice for HIV

    Pagina :937-938

    Susan Rahimi

     
• • ·Infectious disease surveillance update

    Pagina :938

    Ruth Zwizwai

    Mappa Mappa
• • ·Research brief

    Pagina :939

    Sean Cleghorn

    Mappa Mappa
• • ·Johan Willem Mouton

    Pagina :940

    Talha Burki

     
• • ·Malaria, hunger, and starvation in colonial Punjab

    Pagina :941

    Sanjeet Bagcchi

     
• • ·Unspeakable: the truth about HIV-tainted blood in Canada

    Pagina :942

    Márcia Martinho Costa

     
• • ·Evolution and expansion of multidrug-resistant malaria in southeast Asia: a genomic epidemiology study

    Pagina :943-951

    William L Hamilton, Roberto Amato, Rob W van der Pluijm, Christopher G Jacob, Huynh Hong Quang, Nguyen Thanh Thuy-Nhien, Tran Tinh Hien, Bouasy Hongvanthong, Keobouphaphone Chindavongsa, Mayfong Mayxay, Rekol Huy, Rithea Leang, Cheah Huch, Lek Dysoley, Chanaki Amaratunga, Seila Suon, Rick M Fairhurst, Rupam Tripura, Thomas J Peto, Yok Sovann, Podjanee Jittamala, Borimas Hanboonkunupakarn, Sasithon Pukrittayakamee, Nguyen Hoang Chau, Mallika Imwong, Mehul Dhorda, Ranitha Vongpromek, Xin Hui S Chan, Richard J Maude, Richard D Pearson, T Nguyen, Kirk Rockett, Eleanor Drury, Sónia Gonçalves, Nicholas J White, Nicholas P Day, Dominic P Kwiatkowski, Arjen M Dondorp, Olivo Miotto

    Riassunto Riassunto Mappa Mappa   
• • ·Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study

    Pagina :952-961

    Rob W van der Pluijm, Mallika Imwong, Nguyen Hoang Chau, Nhu Thi Hoa, Nguyen Thanh Thuy-Nhien, Ngo Viet Thanh, Podjanee Jittamala, Borimas Hanboonkunupakarn, Kitipumi Chutasmit, Chalermpon Saelow, Ratchadaporn Runjarern, Weerayuth Kaewmok, Rupam Tripura, Thomas J Peto, Sovann Yok, Seila Suon, Sokunthea Sreng, Sivanna Mao, Savuth Oun, Sovannary Yen, Chanaki Amaratunga, Dysoley Lek, Rekol Huy, Mehul Dhorda, Kesinee Chotivanich, Elizabeth A Ashley, Mavuto Mukaka, Naomi Waithira, Phaik Yeong Cheah, Richard J Maude, Roberto Amato, Richard D Pearson, Sónia Gonçalves, Christopher G Jacob, William L Hamilton, Rick M Fairhurst, Joel Tarning, Markus Winterberg, Dominic P Kwiatkowski, Sasithon Pukrittayakamee, Tran Tinh Hien, Nicholas PJ Day, Olivo Miotto, Nicholas J White, Arjen M Dondorp

    Riassunto Riassunto Mappa Mappa   
• • ·Intermittent preventive treatment with dihydroartemisinin–piperaquine and risk of malaria following cessation in young Ugandan children: a double-blind, randomised, controlled trial

    Pagina :962-972

    Mary K Muhindo, Prasanna Jagannathan, Abel Kakuru, Bishop Opira, Peter Olwoch, Jaffer Okiring, Noeline Nalugo, Tamara D Clark, Theodore Ruel, Edwin Charlebois, Margaret E Feeney, Diane V Havlir, Grant Dorsey, Moses R Kamya

    Riassunto Riassunto Mappa Mappa   
• • ·Efficacy and safety of intermittent preventive treatment and intermittent screening and treatment versus single screening and treatment with dihydroartemisinin–piperaquine for the control of malaria in pregnancy in Indonesia: a cluster-randomised, open-label, superiority trial

    Pagina :973-987

    Rukhsana Ahmed, Jeanne R Poespoprodjo, Din Syafruddin, Carole Khairallah, Cheryl Pace, Theda Lukito, Sylvia S Maratina, Puji B S Asih, Maria A Santana-Morales, Emily R Adams, Vera T Unwin, Christopher T Williams, Tao Chen, James Smedley, Duolao Wang, Brian Faragher, Richard N Price, Feiko O ter Kuile

    Riassunto Riassunto Mappa Mappa   
• • ·Immunogenicity and safety of the adjuvanted recombinant zoster vaccine in adults with haematological malignancies: a phase 3, randomised, clinical trial and post-hoc efficacy analysis

    Pagina :988-1000

    Alemnew F Dagnew, Osman Ilhan, Won-Sik Lee, Dariusz Woszczyk, Jae-Yong Kwak, Stella Bowcock, Sang Kyun Sohn, Gabriela Rodriguez Macías, Tzeon-Jye Chiou, Dimas Quiel, Mickael Aoun, Maria Belen Navarro Matilla, Javier de la Serna, Samuel Milliken, John Murphy, Shelly A McNeil, Bruno Salaun, Emmanuel Di Paolo, Laura Campora, Marta López-Fauqued, Mohamed El Idrissi, Anne Schuind, Thomas C Heineman, Peter Van den Steen, Lidia Oostvogels, Zoster-039 study group, Kadir Acar, Boris Afanasyev, Aránzazu Alonso Alonso, Veli-Jukka Anttila, Pere Barba Suñol, Norbert Blesing, Terrance Comeau, Teresa del Campo, Patricia Disperati, Richard Eek, HyeonSeok Eom, Gianluca Gaidano, Sebastian Grosicki, Thierry Guillaume, Wojciech Homenda, William Hwang, Nikolay Ilyin, Anna Johnston, Seok Jin Kim, Ching-Yuan Kuo, Aleksey Kuvshinov, Dong-Gun Lee, Jae Hoon Lee, Je-Jung Lee, Stephane Lepretre, Albert Kwok-Wai Lie, Alessandro Lucchesi, Ahmed Masood, Naheed Mir, Anna Carolina Miranda Castillo, Kathleen Mullane, Alexandr Myasnikov, Raquel Oña Navarrete, Karlis Pauksens, Andrew Peniket, Jaime Perez de Oteyza, David Pohlreich, Humphrey Pullon, Philippe Quittet, Philippe Rodon, Lars Rombo, Olga Samoylova, Johan Sanmartin Berglund, Ariah Schattner, Dominik Selleslag, Marjatta Sinisalo, Faisal Sultan, Koen Theunissen, Paul Turner, Po-Nan Wang, Lucrecia Yáñez San Segundo, Jo-Anne Young, Pierre Zachee, Francesco Zaja

    Riassunto Riassunto Mappa Mappa   
• • ·Safety and efficacy of inactivated varicella zoster virus vaccine in immunocompromised patients with malignancies: a two-arm, randomised, double-blind, phase 3 trial

    Pagina :1001-1012

    Kathleen M Mullane, Vicki A Morrison, Luis H Camacho, Ann Arvin, Shelly A McNeil, Jessie Durrand, Bernadette Campbell, Shu-Chih Su, Ivan S F Chan, Janie Parrino, Susan S Kaplan, Zoran Popmihajlov, Paula W Annunziato, V212 Protocol 011 Trial Team, S Cerana, MO Dictar, P Bonvehi, JP Tregnaghi, L Fein, D Ashley, M Singh, T Hayes, G Playford, O Morrissey, J Thaler, T Kuehr, R Greil, M Pecherstorfer, L Duck, K Van Eygen, M Aoun, B De Prijck, FA Franke, CHE Barrios, AVA Mendes, SV Serrano, RF Garcia, F Moore, JFC Camargo, LA Pires, RS Alves, A Radinov, K Oreshkov, V Minchev, AI Hubenova, T Koynova, I Ivanov, B Rabotilova, V Minchev, PA Petrov, P Chilingirov, S Karanikolov, J Raynov, D Grimard, S McNeil, D Kumar, LM Larratt, K Weiss, R Delage, FJ Diaz-Mitoma, PO Cano, F Couture, P Carvajal, A Yepes, R Torres Ulloa, P Fardella, C Caglevic, C Rojas, E Orellana, P Gonzalez, A Acevedo, KM Galvez, ME Gonzalez, S Franco, JG Restrepo, CA Rojas, C Bonilla, LE Florez, AV Ospina, R Manneh, R Zorica, DV Vrdoljak, M Samarzija, L Petruzelka, J Vydra, J Mayer, D Cibula, J Prausova, G Paulson, M Ontaneda, K Palk, A Vahlberg, R Rooneem, F Galtier, D Postil, F Lucht, F Laine, O Launay, H Laurichesse, X Duval, OA Cornely, B Camerer, J Panse, M Zaiss, H-G Derigs, H Menzel, M Verbeek, V Georgoulias, D Mavroudis, A Anagnostopoulos, E Terpos, D Cortes, J Umanzor, S Bejarano, RW Galeano, RSM Wong, P Hui, P Pedrazzoli, L Ruggeri, F Aversa, A Bosi, G Gentile, A Rambaldi, A Contu, L Marei, A Abbadi, W Hayajneh, J Kattan, F Farhat, G Chahine, J Rutkauskiene, LJ Marfil Rivera, YA Lopez Chuken, H Franco Villarreal, J Lopez Hernandez, H Blacklock, RI Lopez, R Alvarez, AM Gomez, TS Quintana, MDC Moreno Larrea, SJ Zorrilla, E Alarcon, FCA Samanez, PB Caguioa, BJ Tiangco, EM Mora, RD Betancourt-Garcia, D Hallman-Navarro, LJ Feliciano-Lopez, HA Velez-Cortes, F Cabanillas, DE Ganea, TE Ciuleanu, DG Ghizdavescu, L Miron, CL Cebotaru, CI Cainap, R Anghel, MV Dvorkin, OA Gladkov, NV Fadeeva, AA Kuzmin, ON Lipatov, II Zbarskaya, FS Akhmetzyanov, IV Litvinov, BV Afanasyev, M Cherenkova, D Lioznov, IA Lisukov, YA Smirnova, S Kolomietz, H Halawani, YT Goh, L Drgona, J Chudej, M Matejkova, M Reckova, BL Rapoport, WM Szpak, DR Malan, N Jonas, CW Jung, DG Lee, SS Yoon, J Lopez Jimenez, I Duran Martinez, JF Rodriguez Moreno, C Solano Vercet, R de la Camara, M Batlle Massana, S-P Yeh, C-Y Chen, H-H Chou, C-M Tsai, C-H Chiu, N Siritanaratkul, L Norasetthada, V Sriuranpong, K Seetalarom, H Akan, F Dane, MA Ozcan, GH Ozsan, SF Kalayoglu Besisik, A Cagatay, S Yalcin, A Peniket, SR Mullan, KM Dakhil, K Sivarajan, JJ-G Suh, A Sehgal, F Marquez, EG Gomez, MR Mullane, WL Skinner, RJ Behrens, DR Trevarthe, MA Mazurczak, EA Lambiase, CA Vidal, SY Anac, GA Rodrigues, B Baltz, R Boccia, MS Wertheim, CS Holladay, D Zenk, W Fusselman, JL Wade III, AJ Jaslowsk, J Keegan, MO Robinson, RS Go, J Farnen, B Amin, D Jurgens, GF Risi, PG Beatty, T Naqvi, S Parshad, VL Hansen, M Ahmed, PD Steen, S Badarinath, A Dekker, MA Scouros, DE Young, W Graydon Harker, SD Kendall, ML Citron, S Chedid, JG Posada, MK Gupta, S Rafiyath, J Buechler-Price, S Sreenivasappa, CH Chay, JM Burke, SE Young, A Mahmood, JW Kugler, G Gerstner, J Fuloria, ND Belman, R Geller, J Nieva, BP Whittenberger, BMY Wong, TP Cescon, G Abesada-Terk, MJ Guarino, A Zweibach, EN Ibrahim, G Takahashi, MA Garrison, RB Mowat, BS Choi, IA Oliff, J Singh, KA Guter, K Ayrons, KM Rowland, SJ Noga, SB Rao, A Columbie, MT Nualart, GR Cecchi, LT Campos, M Mohebtash, MR Flores, R Rothstein-Rubin, BM O’Connor, G Soori, M Knapp, FG Miranda, BW Goodgame, M Kassem, R Belani, S Sharma, T Ortiz, HL Sonneborn, AB Markowitz, D Wilbur, E Meiri, VS Koo, HS Jhangiani, L Wong, S Sanani, SJ Lawrence, CM Jones, C Murray, C Papageorgiou, JS Gurtler, JL Ascensao, K Seetalarom, ML Venigalla, M D’Andrea, C De Las Casas, DJ Haile, FU Qazi, JL Santander, MR Thomas, VP Rao, M Craig, RJ Garg, R Robles, RM Lyons, RK Stegemoller, S Goel, S Garg, P Lowry, C Lynch, B Lash, T Repka, J Baker, BS Goueli, TC Campbell, DA Van Echo, YJ Lee, EA Reyes, FM Senecal, G Donnelly, P Byeff, R Weiss, T Reid, E Roeland, A Goel, DM Prow, DS Brandt, HG Kaplan, JE Payne, MG Boeckh, PJ Rosen, RR Mena, R Khan, RF Betts, SA Sharp, VA Morrison, D Fitz-Patrick, J Congdon, N Erickson, R Abbasi, S Henderson, A Mehdi, EJ Wos, E Rehmus, L Beltzer, RA Tamayo, T Mahmood, AC Reboli, A Moore, JM Brown, J Cruz, DP Quick, JL Potz, KW Kotz, M Hutchins, NM Chowhan, YD Devabhaktuni, P Braly, RA Berenguer, SC Shambaugh, TJ O’Rourke, WA Conkright, CF Winkler, FEK Addo, JP Duic, KP High, ME Kutner, R Collins, DR Carrizosa, DJ Perry, E Kailath, N Rosen, R Sotolongo, S Shoham, T Chen

    Riassunto Riassunto Mappa Mappa   
• • ·Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial

    Pagina :1013-1022

    Kayvon Modjarrad, Christine C Roberts, Kristin T Mills, Amy R Castellano, Kristopher Paolino, Kar Muthumani, Emma L Reuschel, Merlin L Robb, Trina Racine, Myoung-don Oh, Claude Lamarre, Faraz I Zaidi, Jean Boyer, Sagar B Kudchodkar, Moonsup Jeong, Janice M Darden, Young K Park, Paul T Scott, Celine Remigio, Ajay P Parikh, Megan C Wise, Ami Patel, Elizabeth K Duperret, Kevin Y Kim, Hyeree Choi, Scott White, Mark Bagarazzi, Jeanine M May, Deborah Kane, Hyojin Lee, Gary Kobinger, Nelson L Michael, David B Weiner, Stephen J Thomas, Joel N Maslow

    Riassunto Riassunto Mappa Mappa   
• • ·Characterisation of infectious Ebola virus from the ongoing outbreak to guide response activities in the Democratic Republic of the Congo: a phylogenetic and in vitro analysis

    Pagina :1023-1032

    Laura K McMullan, Mike Flint, Ayan Chakrabarti, Lisa Guerrero, Michael K Lo, Danielle Porter, Stuart T Nichol, Christina F Spiropoulou, César Albariño

    Riassunto Riassunto Mappa Mappa   
• • ·The effect of global change on mosquito-borne disease

    Pagina :e302

    Lydia H V Franklinos, Kate E Jones, David W Redding, Ibrahim Abubakar

    Riassunto Riassunto Mappa Mappa   
• • ·Menstrual toxic shock syndrome: case report and systematic review of the literature

    Pagina :e313

    Selina Berger, Anika Kunerl, Stefan Wasmuth, Philip Tierno, Karoline Wagner, Jan Brügger

    Riassunto Riassunto Mappa Mappa  
• • ·The evolving research agenda for paediatric tuberculosis infection

    Pagina :e322

    James A Seddon, Elizabeth Whittaker, Beate Kampmann, Deborah A Lewinsohn, Muhammad Osman, Anneke C Hesseling, Roxana Rustomjee, Farhana Amanullah

    Riassunto Riassunto Mappa Mappa  
• • ·More medicines alone cannot ensure the treatment of neglected tropical diseases

    Pagina :e330

    Goylette F Chami, Donald A P Bundy

    Riassunto Riassunto Mappa Mappa  
• • ·Pulmonary cryptococcosis mimicking lung cancer

    Pagina :1033

    Masaya Taniwaki, Masahiro Yamasaki, Nobuhisa Ishikawa, Kazuma Kawamoto, Noboru Hattori

     
• • ·Pronounced larva migrans with secondary MRSA infection

    Pagina :1034

    Astrid-Helene Ravn Jørgensen, Kian Zarchi