Sommario

• • ·Acting on misinformation to prevent patient harm

    Pagina :1123

     
• • ·PROPHYLOCHIP: no benefit of second-look surgery plus HIPEC for colorectal peritoneal metastases

    Pagina :1124-1125

    Brendan J Moran

     
• • ·Final results of the UK Age trial on breast cancer screening age

    Pagina :1125-1126

    Anthony B Miller

     
• • ·Chemoradiotherapy plus a SMAC mimetic for locally advanced squamous cell carcinoma of the head and neck

    Pagina :1126-1128

    Jens Voortman

     
• • ·Venetoclax plus obinutuzumab therapy for front-line treatment of chronic lymphocytic leukaemia

    Pagina :1128-1130

    John F Seymour

     
• • ·Maintenance after allogeneic HSCT in acute myeloid leukaemia

    Pagina :1130-1132

    Mohamad Mohty

     
• • ·Carboplatin plus etoposide or topotecan for small-cell lung cancer

    Pagina :1132-1134

    Oscar Arrieta, Luis Lara-Mejía, Zyanya Lucia Zatarain-Barrón

     
• • ·Drug repurposing for cancer treatments: a well-intentioned, but misguided strategy

    Pagina :1134-1136

    Audrey A Tran, Vinay Prasad

     
• • ·Open notes in cancer care: coming soon to patients

    Pagina :1136-1138

    Charlotte Blease, Liz Salmi, Catherine M DesRoches

     
• • ·Gender balance at oncology conferences in China

    Pagina :1138-1140

    Ewelina Biskup, Zhaochen Xin, Kajal Khanna, Tiffany I Leung, Hongwei Zhang

      
• • ·The Lancet Oncology at 20—two decades of influencing the oncology landscape

    Pagina :1140-1141

    David Collingridge

    
• • ·Risk factors for in-hospital mortality in patients with cancer and COVID-19

    Pagina :e406

    Kaibo Guo, Leitao Sun, Li Yuan, Harpreet S Wasan, Shanming Ruan

    
• • ·Risk factors for in-hospital mortality in patients with cancer and COVID-19

    Pagina :e407

    Guosen Zhang, Yang An, Lu Zhang, Longxiang Xie, Xiangqian Guo

    
• • ·Risk factors for in-hospital mortality in patients with cancer and COVID-19 – Authors’ reply

    Pagina :e408

    Kunyu Yang, Yuhan Sheng, Bian Wu, Gang Wu

    
• • ·Terminal agitation and delirium in patients with cancer

    Pagina :e409

    Jun Kako, Hiroto Ishiki, Kohei Kajiwara

    
• • ·Terminal agitation and delirium in patients with cancer

    Pagina :e410

    Mathias Schlögl, Christopher A Jones, Florian Riese

    
• • ·Terminal agitation and delirium in patients with cancer – Authors’ reply

    Pagina :e411

    David Hui, Allison De La Rosa, Jimin Wu, Eduardo Bruera

    
• • ·Atezolizumab plus bevacizumab for unresectable hepatocellular carcinoma

    Pagina :e412

    Xu Yang†, Dongxu Wang†, Jianzhen Lin, Xiaobo Yang, Haitao Zhao

    
• • ·Atezolizumab plus bevacizumab for unresectable hepatocellular carcinoma – Authors’ replys

    Pagina :e413

    Kyung-Hun Lee, Michael S Lee

    
• • ·Ripretinib for advanced gastrointestinal stromal tumours

    Pagina :e414

    Tim J A Dekker

    
• • ·Ripretinib for advanced gastrointestinal stromal tumours – Authors’ reply

    Pagina :e415

    Jean-Yves Blay, Margaret von Mehren

    
• • ·Head and neck surgery recommendations during the COVID-19 pandemic

    Pagina :e416

    Thomas J Galloway, Luiz Paulo Kowalski, Leandro L Matos, Gilberto Castro Junior, John A Ridge

    
• • ·Head and neck surgery recommendations during the COVID-19 pandemic – Author’s reply

    Pagina :e417

    Hisham Mehanna

    
• • ·Correction to Lancet Oncol 2020; 21: 1017–18

    Pagina :e418

    
• • ·Correction to Lancet Oncol 2020; 21: 935–46

    Pagina :e418

    
• • ·Correction to Lancet Oncol 2020; 21: 1125–26

    Pagina :e418

    
• • ·Potential new method for rapid diagnosis of radiation sickness

    Pagina :1142

    Elizabeth Gourd

     
• • ·Patients with cancer hit hard by deadly explosions in Beirut

    Pagina :1143

    Elizabeth Gourd

     
• • ·Vision 2020: looking back and thinking forward on The Lancet Oncology Commissions

    Pagina :1144-1146

    Mary K Gospodarowicz, David A Jaffray, Felicia M Knaul

     
• • ·Second-look surgery plus hyperthermic intraperitoneal chemotherapy versus surveillance in patients at high risk of developing colorectal peritoneal metastases (PROPHYLOCHIP–PRODIGE 15): a randomised, phase 3 study

    Pagina :1147-1154

    Diane Goéré, Olivier Glehen, François Quenet, Jean-Marc Guilloit, Jean-Marc Bereder, Gérard Lorimier, Emilie Thibaudeau, Laurent Ghouti, Amandine Pinto, Jean-Jacques Tuech, Reza Kianmanesh, Michel Carretier, Frédéric Marchal, Catherine Arvieux, Cécile Brigand, Pierre Meeus, Patrick Rat, Sylvaine Durand-Fontanier, Pascale Mariani, Zaher Lakkis, Valeria Loi, Nicolas Pirro, Charles Sabbagh, Matthieu Texier, Dominique Elias, BIG-RENAPE group, M Ducreux, D Malka, V Boige, E Benhamou

    Riassunto Riassunto Mappa Mappa   
• • ·Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA): an open-label, multicentre, phase 1/2, basket study

    Pagina :1155-1164

    Susan M Domchek, Sophie Postel-Vinay, Seock-Ah Im, Yeon Hee Park, Jean-Pierre Delord, Antoine Italiano, Jerome Alexandre, Benoit You, Sara Bastian, Matthew G Krebs, Ding Wang, Saiama N Waqar, Mark Lanasa, Joon Rhee, Haiyan Gao, Vidalba Rocher-Ros, Emma V Jones, Sakshi Gulati, Anna Coenen-Stass, Iwanka Kozarewa, Zhongwu Lai, Helen K Angell, Laura Opincar, Pia Herbolsheimer, Bella Kaufman

    Riassunto Riassunto Mappa Mappa   
• • ·Effect of mammographic screening from age 40 years on breast cancer mortality (UK Age trial): final results of a randomised, controlled trial

    Pagina :1165-1172

    Stephen W Duffy, Daniel Vulkan, Howard Cuckle, Dharmishta Parmar, Shama Sheikh, Robert A Smith, Andrew Evans, Oleg Blyuss, Louise Johns, Ian O Ellis, Jonathan Myles, Peter D Sasieni, Sue M Moss

    Riassunto Riassunto Mappa Mappa   
• • ·Debio 1143 and high-dose cisplatin chemoradiotherapy in high-risk locoregionally advanced squamous cell carcinoma of the head and neck: a double-blind, multicentre, randomised, phase 2 study

    Pagina :1173-1187

    Xu-Shan Sun, Yungan Tao, Christophe Le Tourneau, Yoann Pointreau, Christian Sire, Marie-Christine Kaminsky, Alexandre Coutte, Marc Alfonsi, Pierre Boisselier, Laurent Martin, Jessica Miroir, Jean-Francois Ramee, Jean-Pierre Delord, Florian Clatot, Frederic Rolland, Julie Villa, Nicolas Magne, Olgun Elicin, Elisabeta Gherga, France Nguyen, Cedrick Lafond, Guillaume Bera, Valentin Calugaru, Lionnel Geoffrois, Bruno Chauffert, Angela Zubel, Claudio Zanna, Silvano Brienza, Philippa Crompton, Elisabeth Rouits, Kathrin Gollmer, Sergio Szyldergemajn, Jean Bourhis

    Riassunto Riassunto Mappa Mappa   
• • ·Venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab for previously untreated chronic lymphocytic leukaemia (CLL14): follow-up results from a multicentre, open-label, randomised, phase 3 trial

    Pagina :1188-1200

    Othman Al-Sawaf, Can Zhang, Maneesh Tandon, Arijit Sinha, Anna-Maria Fink, Sandra Robrecht, Olga Samoylova, Anna M Liberati, Javier Pinilla-Ibarz, Stephen Opat, Liliya Sivcheva, Katell Le Dû, Laura M Fogliatto, Carsten U Niemann, Robert Weinkove, Sue Robinson, Thomas J Kipps, Eugen Tausch, William Schary, Matthias Ritgen, Clemens-Martin Wendtner, Karl-Anton Kreuzer, Barbara Eichhorst, Stephan Stilgenbauer, Michael Hallek, Kirsten Fischer

    Riassunto Riassunto Mappa Mappa   
• • ·Sorafenib maintenance in patients with FLT3-ITD acute myeloid leukaemia undergoing allogeneic haematopoietic stem-cell transplantation: an open-label, multicentre, randomised phase 3 trial

    Pagina :1201-1212

    Li Xuan, Yu Wang, Fen Huang, Zhiping Fan, Yajing Xu, Jing Sun, Na Xu, Lan Deng, Xudong Li, Xinquan Liang, Xiaodan Luo, Pengcheng Shi, Hui Liu, Zhixiang Wang, Ling Jiang, Chunzi Yu, Xuan Zhou, Ren Lin, Yan Chen, Sanfang Tu, Xiaojun Huang, Qifa Liu

    Riassunto Riassunto Mappa Mappa   
• • ·Durvalumab with first-line chemotherapy in previously untreated malignant pleural mesothelioma (DREAM): a multicentre, single-arm, phase 2 trial with a safety run-in

    Pagina :1213-1223

    Anna K Nowak, W Joost Lesterhuis, Peey-Sei Kok, Chris Brown, Brett GM Hughes, Deme J Karikios, Thomas John, Steven C-H Kao, Connull Leslie, Alistair M Cook, Nick Pavlakis, Karen Briscoe, Kenneth J O’Byrne, Christos S Karapetis, Wei-Sen Lam, Ailsa Langford, Sonia Yip, Martin R Stockler

    Riassunto Riassunto Mappa Mappa   
• • ·Carboplatin plus etoposide versus topotecan as second-line treatment for patients with sensitive relapsed small-cell lung cancer: an open-label, multicentre, randomised, phase 3 trial

    Pagina :1224-1233

    Nathalie Baize, Isabelle Monnet, Laurent Greillier, Margaux Geier, Hervé Lena, Henri Janicot, Alain Vergnenegre, Jacky Crequit, Regine Lamy, Jean-Bernard Auliac, Jacques Letreut, Hervé Le Caer, Radj Gervais, Eric Dansin, Anne Madroszyk, Patrick-Aldo Renault, Gwenaëlle Le Garff, Lionel Falchero, Henri Berard, Roland Schott, Patrick Saulnier, Christos Chouaid, Groupe Français de Pneumo-Cancérologie 01–13 investigators

    Riassunto Riassunto Mappa Mappa   
• • ·Dabrafenib plus trametinib in patients with BRAF^V600E-mutated biliary tract cancer (ROAR): a phase 2, open-label, single-arm, multicentre basket trial

    Pagina :1234-1243

    Vivek Subbiah, Ulrik Lassen, Elena Élez, Antoine Italiano, Giuseppe Curigliano, Milind Javle, Filippo de Braud, Gerald W Prager, Richard Greil, Alexander Stein, Angelica Fasolo, Jan H M Schellens, Patrick Y Wen, Kert Viele, Aislyn D Boran, Eduard Gasal, Paul Burgess, Palanichamy Ilankumaran, Zev A Wainberg

    Riassunto Riassunto Mappa Mappa   
• • ·Apatinib in patients with advanced chordoma: a single-arm, single-centre, phase 2 study

    Pagina :1244-1252

    Chao Liu, Qi Jia, Haifeng Wei, Xinghai Yang, Tielong Liu, Jian Zhao, Yan Ling, Chenguang Wang, Hongyu Yu, Zhenxi Li, Jian Jiao, Zhipeng Wu, Cheng Yang, Jianru Xiao

    Riassunto Riassunto Mappa Mappa   
• • ·Turning up the heat on non-immunoreactive tumours: opportunities for clinical development

    Pagina :e419

    María Ochoa de Olza, Blanca Navarro Rodrigo, Stefan Zimmermann, George Coukos

    Riassunto Riassunto Mappa Mappa   
• • ·Molecular profiling of neuroendocrine tumours to predict response and toxicity to peptide receptor radionuclide therapy

    Pagina :e431

    Lisa Bodei, Heiko Schöder, Richard P Baum, Ken Herrmann, Jonathan Strosberg, Martyn Caplin, Kjell Öberg, Irvin M Modlin

    Riassunto Riassunto Mappa Mappa   
• • ·Development of paediatric non-stage prognosticator guidelines for population-based cancer registries and updates to the 2014 Toronto Paediatric Cancer Stage Guidelines

    Pagina :e444

    Sumit Gupta, Joanne Aitken, Ute Bartels, Nickhill Bhakta, Mihaela Bucurenci, James D Brierley, Beatriz De Camargo, Eric Chokunonga, Jessica Clymer, Dana Coza, Chris Fraser, Soad Fuentes-Alabi, Gemma Gatta, Thomas Gross, Zsuzsanna Jakab, Betsy Kohler, Tezer Kutluk, Florencia Moreno, Kayo Nakata, Sari Nur, D M Parkin, Lynne Penberthy, Jason Pole, Jenny N Poynter, Kathy Pritchard-Jones, Oscar Ramirez, Lorna Renner, Eva Steliarova-Foucher, Michael Sullivan, Rajaraman Swaminathan, Liesbet Van Eycken, Tushar Vora, A L Frazier

    Riassunto Riassunto Mappa Mappa  
• • ·The science of hope

    Pagina :e452

    Benjamin W Corn, David B Feldman, Isaiah Wexler

    Riassunto Riassunto Mappa Mappa  
• • ·Multiple brown papules at the site of mastectomy for breast cancer

    Pagina :e460

    Florence Bourlond, Dan Lipsker

     
• • ·20 years of The Lancet Oncology: how scientific should oncology be?

    Pagina :e461

    John Lee