Sommario

• Original Research

  • ·“Time Saved” Calculations to Improve Decision-Making in Progressive Disease Studies

    Pagina :529-536

    S.P. Dickson, B. Haaland, C.H. Mallinckrodt, B. Dubois, P. O’Keefe, M. Morgan, O. Peters, A. Fernández Santana, J. Harrison, Achim Schneeberger, S. Hendrix

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  • ·At-home Administration of Gantenerumab by Care Partners to People with Early Alzheimer’s Disease: Feasibility, Safety and Pharmacodynamic Impact

    Pagina :537-548

    Frank G. Boess, M.A. Scelsi, T. Grimmer, R.J. Perry, M. Tonietto, G. Klein, C. Hofmann, M. Salami, J. Wojtowicz, C.J. Lansdall, C. Lane, G.A. Kerchner, J. Smith, R.S. Doody, GRADUATION Investigators and the gantenerumab study group

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  • ·Phase 2A Learnings Incorporated into RewinD-LB, a Phase 2B Clinical Trial of Neflamapimod in Dementia with Lewy Bodies

    Pagina :549-557

    N.D. Prins, W. de Haan, A. Gardner, K. Blackburn, H.-M. Chu, J.E. Galvin, John J. Alam

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  • ·Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU): Trial Satisfaction and Attitudes towards Future Clinical Trials

    Pagina :558-566

    Haiyan Liu, J. Li, E. Ziegemeier, S. Adams, E. McDade, D.B. Clifford, Y. Cao, G. Wang, Y. Li, S.L. Mills, A.M. Santacruz, S. Belyew, J.D. Grill, B.J. Snider, C.J. Mummery, G. Surti, D. Hannequin, D. Wallon, S.B. Berman, I.Z. Jimenez-Velazquez, E.D. Roberson, C.H. van Dyck, L.S. Honig, R. Sanchez-Valle, W.S. Brooks, S. Gauthier, D. Galasko, C.L. Masters, J. Brosch, G.-Y.R. Hsiung, S. Jayadev, M. Formaglio, M. Masellis, R. Clarnette, J. Pariente, B. Dubois, F. Pasquier, R.J. Bateman, Jorge J. Llibre-Guerra, DIAN-TU Study Team

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  • ·Multiomics Blood-Based Biomarkers Predict Alzheimer’s Predementia with High Specificity in a Multicentric Cohort Study

    Pagina :567-581

    B. Souchet, A. Michaïl, M. Heuillet, A. Dupuy-Gayral, E. Haudebourg, C. Pech, A. Berthemy, F. Autelitano, B. Billoir, K. Domoto-Reilly, C. Fowler, T. Grabowski, S. Jayadev, C.L. Masters, Jérôme Braudeau

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  • ·Critical Values of Daily Sedentary Time and Its Longitudinal Association with Mild Cognitive Impairment Considering APOE ε4: A Prospective Cohort Study

    Pagina :582-588

    H. Duan, X. He, T. Yang, N. Xu, Z. Wang, Z. Li, Y. Chen, Y. Du, M. Zhang, J. Yan, C. Sun, G. Wang, F. Ma, Wen Li, Xin Li, Guowei Huang

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  • ·China Initiative for Multi-Domain Intervention (CHINA-IN-MUDI) to Prevent Cognitive Decline: Study Design and Progress

    Pagina :589-600

    S.-Y. Li, X.-Y. Xie, D. Liu, G.-R. Cheng, F.-F. Hu, D.-Y. Zeng, X.-C. Chen, L.-F. Jia, Y.-J. Wang, X.-L. Bu, C. Qiu, F. Gao, J.-G. Gu, M.-F. Liu, Y. Li, Y.-L. Zhou, H.-J. Chang, Y.-M. Ou, L. Xu, Z.-X. Wu, J.-J. Zhang, J.-Y. Wang, L.-Y. Huang, Y.-Y. Cui, J. Zhou, X.-C. Liu, J. Liu, Q.-Q. Nie, D. Song, C. Cai, G.-B. Han, X. Yang, Wei Tan, Jin-Tai Yu, Yan Zeng

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  • ·The Multi-domain Lifestyle Intervention for Cognitive Impairment in Community-Dwelling Older Adults in Hangzhou (The Heritage Study): Study Design and Protocol

    Pagina :601-611

    Xin Xu, T. Pang, Y. Zhou, H. Zhang, A. Ma, C. Yuan, H. Chen, X. Wen, Q. Yang, X. Xu

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  • ·Sustainable Participation in Community Health Programs to Promote a Healthy Lifestyle and Prevent and Protect against Dementia among Rural Taiwanese Middle-Aged and Older Adults

    Pagina :612-619

    L. Chang, Shu-Chuan Chen, P.-Y. Lin, M.-C. Chen, L.-L. Liao, H.-P. Lin, Y.-Y. Tsao, M.-C. Chen

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  • ·The Effects of Different Exercise Interventions on Patients with Subjective Cognitive Decline: A Systematic Review and Network Meta-Analysis

    Pagina :620-631

    R. Chen, B. Zhao, J. Huang, M. Zhang, Y. Wang, J. Fu, H. Liang, Hongrui Zhan

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  • ·Fish and Shellfish Consumption, Cognitive Health and Mortality from Alzheimer’s Disease among US Adults Aged 60 and Older

    Pagina :632-638

    Hongbing Sun

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  • ·Who Benefited Most from the Internet-Based Conversational Engagement RCT (I-CONECT)? Application of the Personalized Medicine Approach to a Behavioral Intervention Study

    Pagina :639-648

    Chao-Yi Wu, K. Yu, S.E. Arnold, S. Das, H.H. Dodge

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  • ·Associations and Potential Multiple Mechanisms between Subjective Hearing Loss and Cognitive Impairment

    Pagina :649-660

    L. Cui, Y.-Y. Tu, Z. Zhang, Y.-H. Guo, Y.-H. Guan, Fang Xie, Qi-Hao Guo

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  • ·Usability of a Web-Based Registry for Preclinical Alzheimer’s Disease: Implications from a Cross-Sectional Online Survey

    Pagina :661-671

    Kenichiro Sato, Y. Niimi, R. Ihara, K. Suzuki, A. Iwata, Takeshi Iwatsubo

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  • ·Anti-Hypertensive Drugs Moderate the Relationship of Blood Pressure with Alzheimer’s Pathologies and Neurodegenerative Markers in Non-Demented Hypertensive Older Adults

    Pagina :672-683

    Y. Guo, C.-C. Tan, M.S. Tan, L. Tan, W. Xu, Alzheimer’s Disease Neuroimaging Initiative

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  • ·24-Hour Blood Pressure Variability Via Ambulatory Monitoring and Risk for Probable Dementia in the SPRINT Trial

    Pagina :684-692

    I.J. Sible, Daniel A. Nation

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  • ·Cognitive Training with Older Adults Using Smartphone and Web-Based Applications: A Scoping Review

    Pagina :693-700

    A.F. Silva, Rui Miguel Silva, E. Murawska-Ciałowicz, G. Zurek, N. Danek, M. Cialowicz, J. Carvalho, F.M. Clemente

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  • ·Polygenic Risk Score Reveals Genetic Heterogeneity of Alzheimer’s Disease between the Chinese and European Populations

    Pagina :701-709

    F. Li, S. Xie, J. Cui, Y. Li, T. Li, Y. Wang, Jianping Jia

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  • ·Longitudinal Impacts of Precision Greenness on Alzheimer’s Disease

    Pagina :710-720

    S.C. Brown, W.W. Aitken, J. Lombard, A. Parrish, J.R. Dewald, R. Ma, S. Messinger, S. Liu, M.I. Nardi, T. Rundek, J. Szapocznik

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• Review

  • ·Association of Vascular Endothelial Growth Factor Levels with Risk of Alzheimer’s Disease: A Systematic Review and Meta-Analysis

    Pagina :721-729

    Seyed Salman Zakariaee, N. Naderi, E. Azizi

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• Original Research

  • ·Serum Tau-A and Tau-C Levels and Their Association with Cognitive Impairment and Dementia Progression in a Memory Clinic Derived Cohort

    Pagina :730-738

    Tobias Melton Axelsen, P. Høgh, A.R. Bihlet, M.A. Karsdal, K. Henriksen, S.G. Hasselbalch, A.H. Simonsen

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  • ·Association of Cognitive Reserve Indicator with Cognitive Decline and Structural Brain Differences in Middle and Older Age: Findings from the UK Biobank

    Pagina :739-748

    W. Yang, J. Wang, J. Guo, A. Dove, Xiuying Qi, D.A. Bennett, Weili Xu

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• Review

  • ·Mendelian Randomization Analysis Reveals Causal Factors behind Alzheimer’s Disease Risk: Evidence, Opportunities, and Challenges

    Pagina :749-758

    X. Feng, L. Zhang, Y. Hou, W. Ma, J. Ma, X. Chang, Lin Yang

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• Original Research

  • ·Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome

    Pagina :759-768

    Matthias Klee, V.T.E. Aho, P. May, A. Heintz-Buschart, Z. Landoulsi, S.R. Jónsdóttir, C. Pauly, L. Pavelka, L. Delacour, A. Kaysen, R. Krüger, P. Wilmes, A.K. Leist, NCER-PD Consortium, Geeta Acharya, Gloria Aguayo, Myriam Alexandre, Muhammad Ali, Wim Ammerlann, Giuseppe Arena, Michele Bassis, Roxane Batutu, Katy Beaumont, Sibylle Béchet, Guy Berchem, Alexandre Bisdorff, Ibrahim Boussaad, David Bouvier, Lorieza Castillo, Gessica Contesotto, Nancy De Bremaeker, Brian Dewitt, Nico Diederich, Rene Dondelinger, Nancy E Ramia, Angelo Ferrari, Katrin Frauenknecht, Joëlle Fritz, Carlos Gamio, Manon Gantenbein, Piotr Gawron, Laura Georges, Soumyabrata Ghosh, Marijus Giraitis, Enrico Glaab, Martine Goergen, Elisa Gómez De Lope, Jérôme Graas, Mariella Graziano, Valentin Groues, Anne Grünewald, Gaël Hammot, Anne-Marie Hanff, Linda Hansen, Michael Heneka, Estelle Henry, Margaux Henry, Sylvia Herbrink, Sascha Herzinger, Alexander Hundt, Nadine Jacoby, Sonja Jónsdóttir, Jochen Klucken, Olga Kofanova, Rejko Krüger, Pauline Lambert, Zied Landoulsi, Roseline Lentz, Laura Longhino, Ana Festas Lopes, Victoria Lorentz, Tainá M. Marques, Guilherme Marques, Patricia Martins Conde, Patrick May, Deborah Mcintyre, Chouaib Mediouni, Francoise Meisch, Alexia Mendibide, Myriam Menster, Maura Minelli, Michel Mittelbronn, Saïda Mtimet, Maeva Munsch, Romain Nati, Ulf Nehrbass, Sarah Nickels, Beatrice Nicolai, Jean-Paul Nicolay, Fozia Noor, Clarissa P.C. Gomes, Sinthuja Pachchek, Claire Pauly, Laure Pauly, Lukas Pavelka, Magali Perquin, Achilleas Pexaras, Armin Rauschenberger, Rajesh Rawal, Dheeraj Reddy Bobbili, Lucie Remark, Ilsé Richard, Olivia Roland, Kirsten Roomp, Eduardo Rosales, Stefano Sapienza, Venkata Satagopam, Sabine Schmitz, Reinhard Schneider, Jens Schwamborn, Raquel Severino, Amir Sharify, Ruxandra Soare, Ekaterina Soboleva, Kate Sokolowska, Maud Theresine, Hermann Thien, Elodie Thiry, Rebecca Ting Jiin Loo, Johanna Trouet, Olena Tsurkalenko, Michel Vaillant, Carlos Vega, Liliana Vilas Boas, Paul Wilmes, Evi Wollscheid-Lengeling, Gelani Zelimkhanov

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  • ·Investigating the Impact of Tea Consumption on Cognitive Function and Exploring Tea-Genetic Interactions in Older Adults Aged 65–105 Years: Findings from the 2002–2018 CLHLS Data

    Pagina :769-779

    L. Yu, M. Yang, K.X. Ye, C. Li, M. Zou, J. Wang, X. Yuan, D. Zheng, C. Sun, Y. Zhang, Q. Feng, A.B. Maier, L. Sun, L. Feng, Yanyu Wang, Huashuai Chen, Yi Zeng

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  • ·Global Burden of Alzheimer’s Disease and Other Dementias Attributed to High Fasting Plasma Glucose from 1990 to 2019

    Pagina :780-786

    M. Wang, K. Huang, Yinzi Jin, Z.-J. Zheng

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  • ·Examining Demographic Factors, Psychosocial Wellbeing and Cardiovascular Health in Subjective Cognitive Decline in the Brain Health Registry Cohort

    Pagina :787-797

    Rachana Tank, A. Diaz, M.T. Ashford, M.J. Miller, J. Eichenbaum, A. Aaronson, B. Landavazo, J. Neuhaus, M.W. Weiner, R.S. Mackin, J. Barnes, R.L. Nosheny

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• Erratum

  • ·Erratum to: Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome

    Pagina :798

    Matthias Klee, V.T.E. Aho, P. May, A. Heintz-Buschart, Z. Landoulsi, S.R. Jónsdóttir, C. Pauly, L. Pavelka, L. Delacour, A. Kaysen, R. Krüger, P. Wilmes, A.K. Leist, NCER-PD Consortium