Sommario

• • ·AAAAI Developing Researcher Award

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• • ·Nomination for AAAAI Award for Outstanding Research Published in the JACI by a Developing Researcher

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• • ·This month’s theme

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• • ·About the cover

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• • ·This month in Beyond Our Pages

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• • ·In-press articles

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• • ·Symbols used in the Table of Contents

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• • ·Editorial Board

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• Reader services

  • ·Information for Readers

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  • ·Newsview-AAAAI

    Pagina :A29

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  • ·CME Activities Calendar

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  • ·Information for category 1 CME Credit

    Pagina :A37

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• Editors' choice

  • ·The Editors’ Choice

    Pagina :541-542

    Donald Y.M. Leung, Harold S. Nelson, Stanley J. Szefler

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• Reviews and feature articles

  • ·The natural history of asthma

    Pagina :543-548

    Charles E. Reed

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  • ·The natural history of asthma

    Pagina :549-550

    
  • ·Mechanisms of airway hyperresponsiveness

    Pagina :551-559

    Donald W. Cockcroft, Beth E. Davis

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  • ·Correction

    Pagina :559

    
  • ·Mechanisms of airway hyperresponsiveness

    Pagina :560-561

    
  • ·Among young children who wheeze, which children will have persistent asthma?

    Pagina :562-564

    Gail G. Shapiro

    

• Asthma diagnosis and treatment

  • ·Biomarker-driven care in asthma: Are we there?

    Pagina :565-568

    Aaron Deykin

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  • ·Does unconventional medicine work through conventional modes of action?

    Pagina :569-573

    Bodo Niggemann, Christoph Grüber

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  • ·Persistence, adherence, and effectiveness of combination therapy among adult patients with asthma

    Pagina :574-581

    Claudine Marceau, Catherine Lemière, Djamal Berbiche, Sylvie Perreault, Lucie Blais

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• Mechanisms of asthma and allergic inflammation

  • ·Pulmonary distribution, regulation, and functional role of Trk receptors in a murine model of asthma

    Pagina :597-605

    Christina Nassenstein, David Dawbarn, Kenneth Pollock, Shelley Jane Allen, Veit Johannes Erpenbeck, Emma Spies, Norbert Krug, Armin Braun

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  • ·IL-25 enhances allergic airway inflammation by amplifying a T_H2 cell–dependent pathway in mice

    Pagina :606-614

    Tomohiro Tamachi, Yuko Maezawa, Kei Ikeda, Shin-ichiro Kagami, Masahiko Hatano, Yohei Seto, Akira Suto, Kotaro Suzuki, Norihiko Watanabe, Yasushi Saito, Takeshi Tokuhisa, Itsuo Iwamoto, Hiroshi Nakajima

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  • ·Effects of established allergen sensitization on immune and airway responses after secondary allergen sensitization

    Pagina :615-621

    Katharina Blumchen, Kerstin Gerhold, Marcus Schwede, Bodo Niggemann, Anzhela Avagyan, Anna-Maria Dittrich, Birgit Wagner, Heimo Breiteneder, Eckard Hamelmann

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  • ·Correlation between peripheral blood T-cell profiles and airway inflammation in atopic asthma

    Pagina :622-626

    Toshihiro Shirai, Naoki Inui, Takafumi Suda, Kingo Chida

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  • ·Associations of a novel IL4RA polymorphism, Ala57Thr, in Greenlander Inuit

    Pagina :627-634

    Siew-Kim Khoo, Guicheng Zhang, Vibeke Backer, Celeste Porsbjerg, Steen Nepper-Christensen, Rhona Creegan, Gareth Baynam, Nicholas de Klerk, Giovanni A. Rossi, Isabel Hagel, Maria C. Di Prisco, Neil Lynch, John Britton, Ian Hall, Arthur W. Musk, Jack Goldblatt, Peter N. Le Souëf

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  • ·Urine leukotriene E₄ levels are associated with decreased pulmonary function in children with persistent airway obstruction

    Pagina :635-640

    Nathan Rabinovitch, Lening Zhang, Erwin W. Gelfand

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  • ·Toll-like receptor 2, 3, and 4 expression and function in human airway smooth muscle

    Pagina :641-648

    Maria B. Sukkar, Shaoping Xie, Nadia M. Khorasani, Onn Min Kon, Rex Stanbridge, Razao Issa, Kian Fan Chung

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  • ·A phosphodiesterase 4 inhibitor inhibits matrix protein deposition in airways in vitro

    Pagina :649-657

    Janette K. Burgess, Brian G.G. Oliver, Maree H. Poniris, Qi Ge, Sarah Boustany, Natalie Cox, Lyn M. Moir, Peter R.A. Johnson, Judith L. Black

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  • ·Association between farm exposure and atopy, according to the CD14 C-159T polymorphism

    Pagina :658-665

    Bénédicte Leynaert, Monique Guilloud-Bataille, David Soussan, Joëlle Benessiano, Armelle Guénégou, Isabelle Pin, Françoise Neukirch

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  • ·Asthma 2005-2006: Bench to bedside

    Pagina :582-586

    Joshua A. Boyce

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  • ·Rhinoviruses in the pathogenesis of asthma: The bronchial epithelium as a major disease target

    Pagina :587-590

    Stephen T. Holgate

    
  • ·Human rhinovirus in bronchial epithelium of infants with recurrent respiratory symptoms

    Pagina :591-596

    Kristiina Malmström, Anne Pitkäranta, Olli Carpen, Anna Pelkonen, L. Pekka Malmberg, Markku Turpeinen, Merja Kajosaari, Seppo Sarna, Harry Lindahl, Tari Haahtela, Mika J. Mäkelä

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• Environmental and occupational respiratory disorders

  • ·Prenatal initiation of endotoxin airway exposure prevents subsequent allergen-induced sensitization and airway inflammation in mice

    Pagina :666-673

    Kerstin Gerhold, Angela Avagyan, Christine Seib, Remo Frei, Johanna Steinle, Birgit Ahrens, Anna-Maria Dittrich, Katharina Blumchen, Roger Lauener, Eckard Hamelmann

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  • ·Cat allergen level: Its determinants and relationship to specific IgE to cat across European centers

    Pagina :674-681

    Joachim Heinrich, Getahun Bero Bedada, Jan-Paul Zock, Susan Chinn, Dan Norbäck, Mario Olivieri, Cecilie Svanes, Michela Ponzio, Giuseppe Verlato, Simona Villani, Deborah Jarvis, Christina Luczynska, for the Indoor Working Group of the European Community Respiratory Health Survey II

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  • ·Distribution and determinants of house dust mite allergens in Europe: The European Community Respiratory Health Survey II

    Pagina :682-690

    Jan-Paul Zock, Joachim Heinrich, Deborah Jarvis, Giuseppe Verlato, Dan Norbäck, Estel Plana, Jordi Sunyer, Susan Chinn, Mario Olivieri, Argo Soon, Simona Villani, Michela Ponzio, Anna Dahlman-Hoglund, Cecilie Svanes, Christina Luczynska, for the Indoor Working Group of the European Community Respiratory Health Survey II

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  • ·Do asthma and allergy influence subsequent pet keeping? An analysis of childhood and adulthood

    Pagina :691-698

    Cecilie Svanes, Jan-Paul Zock, Josep Antó, Shyamali Dharmage, Dan Norbäck, Matthias Wjst, Joachim Heinrich, Deborah Jarvis, Roberto de Marco, Estel Plana, Chantal Raherison, Jordi Sunyer

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• Food allergy, anaphylaxis, dermatology, and drug allergy

  • ·Analysis of the burden of treatment in patients receiving an EpiPen for yellow jacket anaphylaxis

    Pagina :699-704

    Joanne N.G. Oude Elberink, S. van der Heide, Gordon H. Guyatt, Anthony E.J. Dubois

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  • ·Differential allergen sensitization patterns in chestnut allergy with or without associated latex-fruit syndrome

    Pagina :705-710

    Rosa Sánchez-Monge, Carlos Blanco, Gema López-Torrejón, Jose Cumplido, Munia Recas, Javier Figueroa, Teresa Carrillo, Gabriel Salcedo

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  • ·Skin prick tests reveal stable and heritable reduction of allergenic potency of gene-silenced tomato fruits

    Pagina :711-718

    Yvonne Lorenz, Ernesto Enrique, Lien LeQuynh, Kay Fötisch, Mechthild Retzek, Sophia Biemelt, Uwe Sonnewald, Stefan Vieths, Stephan Scheurer

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  • ·Peanut allergen exposure through saliva: Assessment and interventions to reduce exposure

    Pagina :719-724

    Jennifer M. Maloney, Martin D. Chapman, Scott H. Sicherer

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  • ·Correction

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  • ·Hyperresponsive T_H2 cells with enhanced nuclear factor-κB activation induce atopic dermatitis–like skin lesions in Nishiki-nezumi Cinnamon/Nagoya mice

    Pagina :725-733

    Yoshiyuki Tenda, Masakatsu Yamashita, Motoko Y. Kimura, Akihiro Hasegawa, Chiori Shimizu, Masayuki Kitajima, Atsushi Onodera, Akane Suzuki, Nobuo Seki, Toshinori Nakayama

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• Basic and clinical immunology

  • ·Immunization with a low-dose replicon DNA vaccine encoding Phl p 5 effectively prevents allergic sensitization

    Pagina :734-741

    Maximilian Gabler, Sandra Scheiblhofer, Kerstin Kern, Wolfgang W. Leitner, Angelika Stoecklinger, Cornelia Hauser-Kronberger, Beate Alinger, Berta Lechner, Monika Prinz, Susanne Vrtala, Rudolf Valenta, Josef Thalhamer, Richard Weiss

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  • ·Early-life domestic aeroallergen exposure and IgE sensitization at age 4 years

    Pagina :742-748

    Matias Torrent, Jordi Sunyer, Laura Muñoz, Paul Cullinan, Maria Victoria Iturriaga, Cecilia Figueroa, Oriol Vall, Anthony Newman Taylor, Josep Maria Anto

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  • ·Identification of the Syk kinase inhibitor R112 by a human mast cell screen

    Pagina :749-755

    Alexander B. Rossi, Ellen Herlaar, Sylvia Braselmann, Stacey Huynh, Vanessa Taylor, Roy Frances, Sarkiz D. Issakani, Ankush Argade, Rajinder Singh, Donald G. Payan, Esteban S. Masuda

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• Letters to the Editor

  • ·Proinflammatory effects of IL-4 antagonism

    Pagina :756-758

    John W. Steinke, Julie Negri, Richard Enelow, Dawn F. Baramki, Larry Borish

     
  • ·Is the Allergic Rhinitis and its Impact on Asthma classification useful in daily primary care practice?

    Pagina :758-759

    Helen Van Hoecke, Nathan Vastesaeger, Lode Dewulf, Dirk De Bacquer, Paul van Cauwenberge

    

• Correspondence

  • ·Respirable trichothecene mycotoxins can be demonstrated in the air of Stachybotrys chartarum–contaminated buildings

    Pagina :760

    David C. Straus, Stephen C. Wilson

    
  • ·Adverse reactions to fungal metabolic products in mold-contaminated areas

    Pagina :760-761

    Gerald B. Goldstein

    
  • ·Position paper on molds is seriously flawed

    Pagina :761-762

    Vincent A. Marinkovich

    
  • ·The role of airborne mold in chronic rhinosinusitis

    Pagina :762-763

    Jens U. Ponikau, David A. Sherris

    
  • ·Adverse health effects of indoor mold exposure

    Pagina :763

    Allan Lieberman, William Rea, Luke Curtis

    
  • ·How solid is the Academy position paper on mold exposure?

    Pagina :763-764

    Maurice H.V. Strickland

     
  • ·Rigor, transparency, and disclosure needed in mold position paper

    Pagina :764-766

    Ritchie C. Shoemaker, Harriett Ammann, Richard Lipsey, Edward Montz

     
  • ·Nondisclosure of conflicts of interest is perilous to the advancement of science

    Pagina :766-767

    Kaye H. Kilburn, Michael Gray, Sharon Kramer

    
  • ·Reply

    Pagina :767-768

    Robert A. Wood, Robert K. Bush

    
  • ·Reply

    Pagina :768

    Thomas Platts-Mills

    

• Beyond our pages

  • ·Beyond Our Pages

    Pagina :769-770

    Burton Zweiman, Marc E. Rothenberg

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