Sommario

• • ·Cover 1

    Pagina :OFC

    
• • ·Brief Overview of This Month's JACI

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• • ·Table of Contents

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• • ·Editorial Board

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• Reader services

  • ·Information for Readers

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  • ·News & Notes

    Pagina :A22

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  • ·CME Calendar March 2024

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• Reviews and feature articles

  • ·Neuroimmune interplay during type 2 inflammation: Symptoms, mechanisms, and therapeutic targets in atopic diseases

    Pagina :879-893

    Brian Kim, Marc E. Rothenberg, Xin Sun, Claus Bachert, David Artis, Raza Zaheer, Yamo Deniz, Paul Rowe, Sonya Cyr

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  • ·T cells at the interface of neuroimmune communication

    Pagina :894-903

    Jessica M. Reel, Jumana Abbadi, Maureen A. Cox

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  • ·Similarities and differences in peripheral itch and pain pathways in atopic dermatitis

    Pagina :904-912

    Gil Yosipovitch, Brian Kim, Thomas Luger, Ethan Lerner, Martin Metz, Roni Adiri, Juliana M. Canosa, Amy Cha, Sonja Ständer

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  • ·The immune system in neurological diseases: What innate-like T cells have to say

    Pagina :913-923

    Season K. Wyatt-Johnson, Reham Afify, Randy R. Brutkiewicz

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  • ·Navigating the blurred path of mixed neuroimmune signaling

    Pagina :924-938

    Surbhi Gupta, Alice Viotti, Tuany Eichwald, Anais Roger, Eva Kaufmann, Rahmeh Othman, Nader Ghasemlou, Moutih Rafei, Simmie L. Foster, Sebastien Talbot

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  • ·Mast cell–sensory neuron crosstalk in allergic diseases

    Pagina :939-953

    Chunjing Bao, Soman N. Abraham

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  • ·Analytical challenges in omics research on asthma and allergy: A National Institute of Allergy and Infectious Diseases workshop

    Pagina :954-968

    Supinda Bunyavanich, Patrice M. Becker, Matthew C. Altman, Jessica Lasky-Su, Carole Ober, Karsten Zengler, Evgeny Berdyshev, Richard Bonneau, Talal Chatila, Nilanjan Chatterjee, Kian Fan Chung, Colleen Cutcliffe, Wendy Davidson, Gang Dong, Gang Fang, Patricia Fulkerson, Blanca E. Himes, Liming Liang, Rasika A. Mathias, Shuji Ogino, Joseph Petrosino, Nathan D. Price, Eric Schadt, James Schofield, Max A. Seibold, Hanno Steen, Lisa Wheatley, Hongmei Zhang, Alkis Togias, Kohei Hasegawa

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• The Editors' choice

  • ·The Editors’ Choice

    Pagina :969-974

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• News beyond our pages

  • ·News beyond our pages

    Pagina :975-976

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• Paradigms and perspectives

  • ·Peripheral somatosensory neurons listen and orchestrate the immune response

    Pagina :977-979

    Geoffroy Laumet

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  • ·High metabolite concentrations in portal venous blood as a possible mechanism for microbiota effects on the immune system and Western diseases

    Pagina :980-982

    Quanbo Wang, Charles R. Mackay

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• Editorials

  • ·Unveiling the reasons for disparities in prevalence of asthma and allergic conditions in Black children: The role of socioeconomic status

    Pagina :983-984

    Alex Federman, Juan P. Wisnivesky

     
  • ·2023: The year in review

    Pagina :985-987

    Zuhair K. Ballas

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• Asthma and lower airway disease

  • ·Airway hyperresponsiveness correlates with airway TSLP in asthma independent of eosinophilic inflammation

    Pagina :988

    Louise Munkholm Andreasson, Nanna Dyhre-Petersen, Morten Hvidtfeldt, Gustav Ørting Jørgensen, Anna Von Bülow, Ditte Kjærsgaard Klein, Lena Uller, Jonas Erjefält, Celeste Porsbjerg, Asger Sverrild

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  • ·Cannabinoid receptor 2 as a regulator of inflammation induced oleoylethanolamide in eosinophilic asthma

    Pagina :998

    Eun-Kyung Kwon, Youngwoo Choi, Soyoon Sim, Young-Min Ye, Yoo Seob Shin, Hae-Sim Park, Ga-Young Ban

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  • ·Asthmatic patients with high serum amyloid A have proinflammatory HDL: Implications for augmented systemic and airway inflammation

    Pagina :1010

    Xianglan Yao, Maryann Kaler, Xuan Qu, Rama Satyanarayana Raju Kalidhindi, Denis Sviridov, Amaury Dasseux, Eric Barr, Karen Keeran, Kenneth R. Jeffries, Zu-Xi Yu, Meixia Gao, Scott Gordon, Amisha V. Barochia, Joni Mills, Shahid Shahid, Nargues A. Weir, Or Kalchiem-Dekel, Patricia Theard, Martin P. Playford, Mario Stylianou, Wendy Fitzgerald, Alan T. Remaley, Stewart J. Levine

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• Rhinitis, sinusitis, and ocular allergy

  • ·Aberrant follicular regulatory T cells associate with immunoglobulin hyperproduction in nasal polyps with ectopic lymphoid tissues

    Pagina :1025-1039

    Jia Song, Hai Wang, Zhe-Zheng Wang, Cui-Lian Guo, Wen-Xuan Xiang, Jing-Xian Li, Zhi-Chao Wang, Ji-Xin Zhong, Kun Huang, Robert P. Schleimer, Yin Yao, Zheng Liu

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• Atopic dermatitis and inflammatory skin disease

  • ·Efficacy and safety of rademikibart (CBP-201), a next-generation mAb targeting IL-4Rα, in adults with moderate to severe atopic dermatitis: A phase 2 randomized trial (CBP-201-WW001)

    Pagina :1040

    Jonathan I. Silverberg, Bruce Strober, Brian Feinstein, Jinhua Xu, Emma Guttman-Yassky, Eric L. Simpson, Pauline Li, Malinda Longphre, Jing Song, Jiawang Guo, Jang Yun, Belinda Williams, Wubin Pan, Selwyn Ho, Raúl Collazo, Zheng Wei

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• Food allergy and gastrointestinal disease

  • ·IgE and anaphylaxis specific to the carbohydrate alpha-gal depend on IL-4

    Pagina :1050

    Miriam Hils, Nils Hoffard, Caterina Iuliano, Luisa Kreft, Neera Chakrapani, Kyra Swiontek, Konrad Fischer, Bernadette Eberlein, Martin Köberle, Jörg Fischer, Christiane Hilger, Caspar Ohnmacht, Susanne Kaesler, Florian Wölbing, Tilo Biedermann

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  • ·Persistent esophageal changes after histologic remission in eosinophilic esophagitis

    Pagina :1063-1072

    Melanie A. Ruffner, Tetsuo Shoda, Megha Lal, Zoe Mrozek, Amanda B. Muir, Jonathan M. Spergel, Evan S. Dellon, Marc E. Rothenberg

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• Anaphylaxis, drug allergy, urticaria, and angioedema

  • ·Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus

    Pagina :1073-1082

    Carina M. Mathey, Carlo Maj, Niclas Eriksson, Kristi Krebs, Julia Westmeier, Friederike S. David, Maria Koromina, Annika B. Scheer, Nora Szabo, Bettina Wedi, Dorothea Wieczorek, Philipp M. Amann, Harald Löffler, Lukas Koch, Clemens Schöffl, Heinrich Dickel, Nomun Ganjuur, Thorsten Hornung, Timo Buhl, Jens Greve, Gerda Wurpts, Emel Aygören-Pürsün, Michael Steffens, Stefan Herms, Stefanie Heilmann-Heimbach, Per Hoffmann, Börge Schmidt, Laven Mavarani, Trine Andresen, Signe Bek Sørensen, Vibeke Andersen, Ulla Vogel, Mikael Landén, Cynthia M. Bulik, Estonian Biobank Research Team, DBDS Genomic Consortium, Anette Bygum, Patrik K.E. Magnusson, Christian von Buchwald, Pär Hallberg, Sisse Rye Ostrowski, Erik Sørensen, Ole B. Pedersen, Henrik Ullum, Christian Erikstrup, Henning Bundgaard, Lili Milani, Eva Rye Rasmussen, Mia Wadelius, Jonas Ghouse, Bernhardt Sachs, Markus M. Nöthen, Andreas J. Forstner

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• Mechanisms of allergy/immunology

  • ·Impaired interferon response in plasmacytoid dendritic cells from children with persistent wheeze

    Pagina :1083-1094

    Isabelle Coenen, Emma de Jong, Anya C. Jones, Siew-Kim Khoo, Shihui Foo, Shanshan Wu Howland, Florent Ginhoux, Peter N. Le Souëf, Patrick G. Holt, Deborah H. Strickland, Ingrid A. Laing, Jonatan Leffler

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• Translational and clinical immunology

  • ·Granzyme K– and amphiregulin-expressing cytotoxic T cells and activated extrafollicular B cells are potential drivers of IgG4-related disease

    Pagina :1095-1112

    Risako Koga, Takashi Maehara, Ryuichi Aoyagi, Ryusuke Munemura, Yuka Murakami, Atsushi Doi, Michihito Kono, Hidetaka Yamamoto, Hiroaki Niiro, Tamotsu Kiyoshima, Mika Tanabe, Toshiaki Nakano, Yuta Matsukuma, Mitsuhiro Kawano, John H. Stone, Shiv Pillai, Seiji Nakamura, Shintaro Kawano

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  • ·MYSM1 attenuates DNA damage signals triggered by physiologic and genotoxic DNA breaks

    Pagina :1113

    Brendan Mathias, David O’Leary, Nermina Saucier, Faiz Ahmad, Lynn S. White, Le’Mark Russell, Marwan Shinawi, Matthew J. Smith, Roshini S. Abraham, Megan A. Cooper, Maleewan Kitcharoensakkul, Abby M. Green, Jeffrey J. Bednarski

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  • ·Recapitulating primary immunodeficiencies with expanded potential stem cells: Proof of concept with STAT1 gain of function

    Pagina :1125-1139

    Xueyan Liu, Vera S.F. Chan, Kenneth G.C. Smith, Chang Ming, Chung Sze Or, Faria T.W. Tsui, Bo Gao, Matthew C. Cook, Pentao Liu, Chak Sing Lau, Philip Hei Li

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• Environmental and occupational disease

  • ·Lower socioeconomic status may help explain racial disparities in asthma and atopic dermatitis prevalence: A mediation analysis

    Pagina :1140

    Emily A. Croce, Layla Parast, Darlene Bhavnani, Elizabeth C. Matsui

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• Brief reports

  • ·The circadian metabolome of atopic dermatitis

    Pagina :1148-1154

    Grace Ratley, Jordan Zeldin, Prem Prashant Chaudhary, Manoj Yadav, Amy S. Paller, Phyllis Zee, Ian A. Myles, Anna Fishbein

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  • ·Influence of pathogenic filaggrin variants on dupilumab treatment in atopic dermatitis

    Pagina :1155

    Julia Clabbers, Celeste Boesjes, Lotte Spekhorst, Marike W. van Gisbergen, Emmy Maas, Josephine Marshall, Renske Janssen, Miranda Janssen, Nicolaas Zuithoff, Peter Steijlen, Marlies de Graaf, Michel van Geel, Marjolein de Bruin-Weller, Antoni Gostyński

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  • ·Grading immediate drug reactions: Adopting a robust diagnostic approach

    Pagina :1162

    Timothy J. Watts

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  • ·Reply

    Pagina :1162-1163

    David A. Khan, Kimberly G. Blumenthal

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  • ·Food sensitization and cardiovascular mortality: An intriguing association in need of further study

    Pagina :1163-1165

    Marcus Shaker, Elissa M. Abrams, John Oppenheimer, Aikaterini Anagnostou, Christopher D. Codispoti, David B.K. Golden, Matthew Greenhawt, David Stukus, Melissa Moore- Clingenpeel, Sarah W. Hughes, Douglas P. Mack, S. Shahzad Mustafa, David M. Lang

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  • ·Reply

    Pagina :1165-1166

    Corinne Keet, Emily McGowan, David Jacobs, Wendy Post, Thomas Platts-Mills, Jeffery Wilson

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  • ·Corrigendum

    Pagina :1167