Sommario

• • ·Cover 1

    Pagina :OFC

    
• • ·Brief Overview of This Month's JACI

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• • ·Table of Contents

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• • ·Editorial Board

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• Reader services

  • ·Information for Readers

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  • ·News & Notes-AAAAI

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  • ·CME Calendar March 2024

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• Reviews and feature articles

  • ·Tapinarof validates the aryl hydrocarbon receptor as a therapeutic target: A clinical review

    Pagina :1-10

    Jonathan I. Silverberg, Mark Boguniewicz, Francisco J. Quintana, Rachael A. Clark, Lara Gross, Ikuo Hirano, Anna M. Tallman, Philip M. Brown, Doral Fredericks, David S. Rubenstein, Kimberly A. McHale

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  • ·Interactions between skin-resident dendritic and Langerhans cells and pain-sensing neurons

    Pagina :11-19

    Natalie C. Wilcox, Golnar Taheri, Katherine Halievski, Sebastien Talbot, Jaqueline R. Silva, Nader Ghasemlou

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  • ·Biologic and small-molecule therapy for treating moderate to severe atopic dermatitis: Mechanistic considerations

    Pagina :20-30

    Camille Rothenberg-Lausell, Jonathan Bar, Dante Dahabreh, Yael Renert-Yuval, Ester Del Duca, Emma Guttman-Yassky

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  • ·Exploring the skin microbiome in atopic dermatitis pathogenesis and disease modification

    Pagina :31-41

    Claudia Hülpüsch, Robin Rohayem, Matthias Reiger, Claudia Traidl-Hoffmann

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  • ·Inflammatory memory in psoriasis: From remission to recurrence

    Pagina :42-50

    Luc Francis, Francesca Capon, Catherine H. Smith, Muzlifah Haniffa, Satveer K. Mahil

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  • ·Gene editing in allergic diseases: Identification of novel pathways and impact of deleting allergen genes

    Pagina :51-58

    Meiqin Wang, Michaela Schedel, Erwin W. Gelfand

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  • ·Volunteerism Addressing Environmental Disparities in Allergy (VAEDIA): The presidential initiative to combat environmental injustice in allergy and immunology—a Work Group Report of the AAAAI VAEDIA task force

    Pagina :59-67

    Mahboobeh Mahdavinia, Jill A. Poole, Andrea J. Apter, Susan E. Pacheco, Andrea A. Pappalardo, Elizabeth C. Matsui, Carla M. Davis, Jonathan A. Bernstein

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• The Editors' choice

  • ·The Editors’ Choice

    Pagina :68-73

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• News beyond our pages

  • ·News beyond our pages - July 2024

    Pagina :74-75

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• Paradigms and perspectives

  • ·The coming of age of protein degraders as anti-inflammatory therapeutics

    Pagina :76-78

    Johann E. Gudjonsson, Stephan Weidinger, Kenji Kabashima

     
  • ·Population descriptors in asthma and allergy research: Time to regroup

    Pagina :79-81

    Carole Ober, Christine L.M. Joseph, John Novembre

     

• Editorials

  • ·Impulse oscillometry: Gathering speed in the assessment of preschool lung function

    Pagina :82-83

    Theresa W. Guilbert, Karen M. McDowell

    
  • ·Utility of T_H2 cell biomarkers to predict outcomes and treatment response in children with asthma

    Pagina :84-85

    W. Gerald Teague, Cameron Griffiths

     
  • ·Trajectories and phenotypes of rhinitis and wheeze

    Pagina :86-87

    Markus Johannes Ege

     
  • ·Mechanisms underlying skin inflammation of DOCK8 deficiency

    Pagina :88-90

    Mathieu Fusaro, Loïc Dupré

     
  • ·Dupilumab for chronic spontaneous urticaria—marvelous or meek?

    Pagina :91-93

    Sameer K. Mathur, Daniel L. Rosenberg, Ravi K. Viswanathan

     

• Asthma and lower airway disease

  • ·Preschool impulse oscillometry predicts active asthma and impaired lung function at school age

    Pagina :94

    Hanna M. Knihtilä, Benjamin J. Stubbs, Vincent J. Carey, Nancy Laranjo, Robert S. Zeiger, Leonard B. Bacharier, George T. O’Connor, Scott T. Weiss, Augusto A. Litonjua

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  • ·Blood eosinophils and fractional exhaled nitric oxide are prognostic and predictive biomarkers in childhood asthma

    Pagina :101-110

    Leonard B. Bacharier, Ian D. Pavord, Jorge F. Maspero, Daniel J. Jackson, Alessandro G. Fiocchi, Xuezhou Mao, Juby A. Jacob-Nara, Yamo Deniz, Elizabeth Laws, Leda P. Mannent, Nikhil Amin, Bolanle Akinlade, Heribert W. Staudinger, David J. Lederer, Megan Hardin

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• Rhinitis, sinusitis, and ocular allergy

  • ·Trajectory analysis of rhinitis in a birth cohort from lower-income New York City neighborhoods

    Pagina :111-119

    Nina M. Flores, Stephanie Lovinsky-Desir, Adnan Divjan, Lori A. Hoepner, Jungang Zou, Rachel L. Miller, Julie B. Herbstman, Frederica P. Perera, Matthew S. Perzanowski, Qixuan Chen

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  • ·Epithelium-derived kallistatin promotes CD4⁺ T-cell chemotaxis to T_H2-type inflammation in chronic rhinosinusitis

    Pagina :120-130

    Lijie Jiang, Haocheng Tang, Tengjiao Lin, Yifeng Jiang, Yanmei Li, Wenxiang Gao, Jie Deng, Zhaoqi Huang, Chuxin Chen, Jianbo Shi, Ti Zhou, Yinyan Lai

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• Atopic dermatitis and inflammatory skin disease

  • ·Antibiotics taken within the first year of life are linked to infant gut microbiome disruption and elevated atopic dermatitis risk

    Pagina :131-142

    Courtney Hoskinson, Maria V. Medeleanu, Myrtha E. Reyna, Darlene L.Y. Dai, Biswajit Chowdhury, Theo J. Moraes, Piushkumar J. Mandhane, Elinor Simons, Anita L. Kozyrskyj, Meghan B. Azad, Charisse Petersen, Stuart E. Turvey, Padmaja Subbarao

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  • ·Regulatory T-cell dysfunction and cutaneous exposure to Staphylococcus aureus underlie eczema in DOCK8 deficiency

    Pagina :143-156

    Hazel Wilkie, Mrinmoy Das, Tyler Pelovitz, Wayne Bainter, Brian Woods, Mohammed Alasharee, Ali Sobh, Safa Baris, Sevgi Bilgic Eltan, Waleed Al-Herz, Mohamed-Ridha Barbouche, Imen Ben-Mustapha, Meriem Ben-Ali, Mohamed T.H. Sallam, Amany Awad, Sohilla Lotfy, Aisha El Marsafy, Moushira Ezzelarab, Michael Farrar, Brigitta A.R. Schmidt, Monali NandyMazumdar, Emma Guttman-Yassky, Anthony Sheets, Katie Maria Vidic, George Murphy, Patrick M. Schlievert, Janet Chou, Juan Manuel Leyva-Castillo, Erin Janssen, Maheshwor Timilshina, Raif S. Geha

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• Food allergy and gastrointestinal disease

  • ·Metabolomics identifies phenotypic biomarkers of amino acid metabolism in milk allergy and sensitized tolerance

    Pagina :157-167

    Qiaozhi Zhang, Hui Wang, Shenyu Zhang, Mingwu Chen, Zhongshan Gao, Jinlyu Sun, Jizhou Wang, Linglin Fu

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  • ·Metabolomic profiles during early childhood and risk of food allergies and asthma in multiethnic children from a prospective birth cohort

    Pagina :168-178

    Xiumei Hong, Kari Nadeau, Guoying Wang, Ben Larman, Kellie N. Smith, Colleen Pearson, Hongkai Ji, Pamela Frischmeyer-Guerrerio, Liming Liang, Frank B. Hu, Xiaobin Wang

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• Anaphylaxis, drug allergy, urticaria, and angioedema

  • ·Deucrictibant for angioedema due to acquired C1-inhibitor deficiency: A randomized-controlled trial

    Pagina :179-183

    Remy S. Petersen, Lauré M. Fijen, Johannes P. Kelder, Danny M. Cohn

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  • ·Dupilumab in patients with chronic spontaneous urticaria (LIBERTY-CSU CUPID): Two randomized, double-blind, placebo-controlled, phase 3 trials

    Pagina :184-194

    Marcus Maurer, Thomas B. Casale, Sarbjit S. Saini, Moshe Ben-Shoshan, Ana M. Giménez-Arnau, Jonathan A. Bernstein, Akiko Yagami, Aleksandra Stjepanovic, Allen Radin, Heribert W. Staudinger, Naimish Patel, Nikhil Amin, Bolanle Akinlade, Chunpeng Fan, Deborah Bauer, George D. Yancopoulos, Kiran Patel, Leda P. Mannent, Elizabeth Laws

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• Translational and clinical immunology

  • ·Hematopoietic stem cell gene editing rescues B-cell development in X-linked agammaglobulinemia

    Pagina :195

    Sameer Bahal, Marta Zinicola, Shefta E Moula, Thomas E. Whittaker, Andrea Schejtman, Asma Naseem, Elena Blanco, Winston Vetharoy, Yi-Ting Hu, Rajeev Rai, Eduardo Gomez-Castaneda, Catarina Cunha-Santos, Siobhan O. Burns, Emma C. Morris, Claire Booth, Giandomenico Turchiano, Alessia Cavazza, Adrian J. Thrasher, Giorgia Santilli

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• Environmental and occupational disease

  • ·Landscape fire smoke airway exposure impairs respiratory and cardiac function and worsens experimental asthma

    Pagina :209

    Henry M. Gomez, Tatt J. Haw, Dusan Ilic, Peter Robinson, Chantal Donovan, Amanda J. Croft, Kanth S. Vanka, Ellen Small, Olivia R. Carroll, Richard Y. Kim, Jemma R. Mayall, Tesfalidet Beyene, Thava Palanisami, Doan T.M. Ngo, Graeme R. Zosky, Elizabeth G. Holliday, Megan E. Jensen, Vanessa M. McDonald, Vanessa E. Murphy, Peter G. Gibson, Jay C. Horvat

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• Brief reports

  • ·Prevention of allergic reactions during oxaliplatin desensitization through inhibition of Bruton tyrosine kinase

    Pagina :222

    Kristin A. Erickson, James E. Norton, Jennifer Law, Nicole Soriano, Malgorzata Strojny, Nicole Gentry, Morgan Fried, Bruce S. Bochner, Sheetal Kircher, Whitney W. Stevens

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  • ·Loss-of-phosphorylation of IKZF1 results in gain-of-function associated with immune dysregulation

    Pagina :229

    Akihiro Hoshino, Benoît Heid Picard, Sophia Polychronopoulou, Charikleia Kelaidi, Saba Azarnoush, Sven Kracker, Frédéric Rieux-Laucat, David Boutboul, Sylvain Latour

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  • ·Renal complications in patients with predominantly antibody deficiency in the United States Immune Deficiency Network (USIDNET)

    Pagina :237

    Emma Materne, Baijun Zhou, Daniel DiGiacomo, Jocelyn R. Farmer, Ramsay Fuleihan, Kathleen E. Sullivan, Charlotte Cunningham-Rundles, Zuhair K. Ballas, Daniel Suez, Sara Barmettler, USIDNET Consortium

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  • ·Corrigendum

    Pagina :243